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WIPI1 (WD repeat domain, phosphoinositide interacting 1)

Identity

Alias (NCBI)ATG18
ATG18A
WIPI49
HGNC (Hugo) WIPI1
HGNC Alias symbFLJ10055
WIPI49
ATG18
ATG18A
LocusID (NCBI) 55062
Atlas_Id 46381
Location 17q24.2  [Link to chromosome band 17q24]
Location_base_pair Starts at 68421281 and ends at 68457496 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCAS3 (17q23.2) / WIPI1 (17q24.2)MOB2 (11p15.5) / WIPI1 (17q24.2)PTPN18 (2q21.1) / WIPI1 (17q24.2)
SERPINB4 (18q21.33) / WIPI1 (17q24.2)WIPI1 (17q24.2) / AC040934.1 ()WIPI1 (17q24.2) / WIPI1 (17q24.2)
BCAS3 17q23.2 / WIPI1 17q24.2WIPI1 17q24.2 AC040934.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)WIPI1   25471
Cards
Entrez_Gene (NCBI)WIPI1    WD repeat domain, phosphoinositide interacting 1
AliasesATG18; ATG18A; WIPI49
GeneCards (Weizmann)WIPI1
Ensembl hg19 (Hinxton)ENSG00000070540 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000070540 [Gene_View]  ENSG00000070540 [Sequence]  chr17:68421281-68457496 [Contig_View]  WIPI1 [Vega]
ICGC DataPortalENSG00000070540
TCGA cBioPortalWIPI1
AceView (NCBI)WIPI1
Genatlas (Paris)WIPI1
SOURCE (Princeton)WIPI1
Genetics Home Reference (NIH)WIPI1
Genomic and cartography
GoldenPath hg38 (UCSC)WIPI1  -     chr17:68421281-68457496 -  17q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WIPI1  -     17q24.2   [Description]    (hg19-Feb_2009)
GoldenPathWIPI1 - 17q24.2 [CytoView hg19]  WIPI1 - 17q24.2 [CytoView hg38]
ImmunoBaseENSG00000070540
Genome Data Viewer NCBIWIPI1 [Mapview hg19]  
OMIM609224   
Gene and transcription
Genbank (Entrez)AK000917 AK301830 AY691424 BC039867 BI764142
RefSeq transcript (Entrez)NM_001320772 NM_017983
Consensus coding sequences : CCDS (NCBI)WIPI1
Gene ExpressionWIPI1 [ NCBI-GEO ]   WIPI1 [ EBI - ARRAY_EXPRESS ]   WIPI1 [ SEEK ]   WIPI1 [ MEM ]
Gene Expression Viewer (FireBrowse)WIPI1 [ Firebrowse - Broad ]
GenevisibleExpression of WIPI1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55062
GTEX Portal (Tissue expression)WIPI1
Human Protein AtlasENSG00000070540-WIPI1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5MNZ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5MNZ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5MNZ9
PhosPhoSitePlusQ5MNZ9
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_dom_sf    WIPI1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WIPI1
SuperfamilyQ5MNZ9
AlphaFold pdb e-kbQ5MNZ9   
Human Protein Atlas [tissue]ENSG00000070540-WIPI1 [tissue]
HPRD08540
Protein Interaction databases
DIP (DOE-UCLA)Q5MNZ9
IntAct (EBI)Q5MNZ9
BioGRIDWIPI1
STRING (EMBL)WIPI1
ZODIACWIPI1
Ontologies - Pathways
QuickGOQ5MNZ9
Ontology : AmiGOautophagosome assembly  Golgi membrane  phagophore assembly site  autophagosome membrane  autophagy of mitochondrion  signaling receptor binding  protein binding  cytoplasm  trans-Golgi network  cytosol  cytosol  cytoskeleton  protein lipidation  autophagy  cellular response to starvation  endosome membrane  macroautophagy  extrinsic component of membrane  clathrin-coated vesicle  estrogen receptor binding  phosphatidylinositol-3-phosphate binding  phosphatidylinositol-3-phosphate binding  phagophore assembly site membrane  phagophore assembly site membrane  protein localization to phagophore assembly site  IRE1-mediated unfolded protein response  autophagy of nucleus  vesicle targeting, trans-Golgi to endosome  androgen receptor binding  phosphatidylinositol-3,5-bisphosphate binding  phosphatidylinositol-3,5-bisphosphate binding  
Ontology : EGO-EBIautophagosome assembly  Golgi membrane  phagophore assembly site  autophagosome membrane  autophagy of mitochondrion  signaling receptor binding  protein binding  cytoplasm  trans-Golgi network  cytosol  cytosol  cytoskeleton  protein lipidation  autophagy  cellular response to starvation  endosome membrane  macroautophagy  extrinsic component of membrane  clathrin-coated vesicle  estrogen receptor binding  phosphatidylinositol-3-phosphate binding  phosphatidylinositol-3-phosphate binding  phagophore assembly site membrane  phagophore assembly site membrane  protein localization to phagophore assembly site  IRE1-mediated unfolded protein response  autophagy of nucleus  vesicle targeting, trans-Golgi to endosome  androgen receptor binding  phosphatidylinositol-3,5-bisphosphate binding  phosphatidylinositol-3,5-bisphosphate binding  
NDEx NetworkWIPI1
Atlas of Cancer Signalling NetworkWIPI1
Wikipedia pathwaysWIPI1
Orthology - Evolution
OrthoDB55062
GeneTree (enSembl)ENSG00000070540
Phylogenetic Trees/Animal Genes : TreeFamWIPI1
Homologs : HomoloGeneWIPI1
Homology/Alignments : Family Browser (UCSC)WIPI1
Gene fusions - Rearrangements
Fusion : MitelmanBCAS3/WIPI1 [17q23.2/17q24.2]  
Fusion : QuiverWIPI1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWIPI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WIPI1
dbVarWIPI1
ClinVarWIPI1
MonarchWIPI1
1000_GenomesWIPI1 
Exome Variant ServerWIPI1
GNOMAD BrowserENSG00000070540
Varsome BrowserWIPI1
ACMGWIPI1 variants
VarityQ5MNZ9
Genomic Variants (DGV)WIPI1 [DGVbeta]
DECIPHERWIPI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWIPI1 
Mutations
ICGC Data PortalWIPI1 
TCGA Data PortalWIPI1 
Broad Tumor PortalWIPI1
OASIS PortalWIPI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWIPI1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DWIPI1
Mutations and Diseases : HGMDWIPI1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaWIPI1
DgiDB (Drug Gene Interaction Database)WIPI1
DoCM (Curated mutations)WIPI1
CIViC (Clinical Interpretations of Variants in Cancer)WIPI1
Cancer3DWIPI1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609224   
Orphanet
DisGeNETWIPI1
MedgenWIPI1
Genetic Testing Registry WIPI1
NextProtQ5MNZ9 [Medical]
GENETestsWIPI1
Target ValidationWIPI1
Huge Navigator WIPI1 [HugePedia]
ClinGenWIPI1
Clinical trials, drugs, therapy
MyCancerGenomeWIPI1
Protein Interactions : CTDWIPI1
Pharm GKB GenePA142670575
PharosQ5MNZ9
Clinical trialWIPI1
Miscellaneous
canSAR (ICR)WIPI1
HarmonizomeWIPI1
DataMed IndexWIPI1
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXWIPI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:38:24 CEST 2021

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