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WISP1 (WNT1 inducible signaling pathway protein 1)

Identity

Alias_symbol (synonym)CCN4
Other aliasWISP1c
WISP1i
WISP1tc
HGNC (Hugo) WISP1
LocusID (NCBI) 8840
Atlas_Id 42813
Location 8q24.22  [Link to chromosome band 8q24]
Location_base_pair Starts at 133191039 and ends at 133231689 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CHI3L1 (1q32.1) / WISP1 (8q24.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WISP1   12769
Cards
Entrez_Gene (NCBI)WISP1  8840  WNT1 inducible signaling pathway protein 1
AliasesCCN4; WISP1c; WISP1i; WISP1tc
GeneCards (Weizmann)WISP1
Ensembl hg19 (Hinxton)ENSG00000104415 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104415 [Gene_View]  chr8:133191039-133231689 [Contig_View]  WISP1 [Vega]
ICGC DataPortalENSG00000104415
TCGA cBioPortalWISP1
AceView (NCBI)WISP1
Genatlas (Paris)WISP1
WikiGenes8840
SOURCE (Princeton)WISP1
Genetics Home Reference (NIH)WISP1
Genomic and cartography
GoldenPath hg38 (UCSC)WISP1  -     chr8:133191039-133231689 +  8q24.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WISP1  -     8q24.22   [Description]    (hg19-Feb_2009)
EnsemblWISP1 - 8q24.22 [CytoView hg19]  WISP1 - 8q24.22 [CytoView hg38]
Mapping of homologs : NCBIWISP1 [Mapview hg19]  WISP1 [Mapview hg38]
OMIM603398   
Gene and transcription
Genbank (Entrez)AB034725 AF100779 AI347990 AK027294 AK293031
RefSeq transcript (Entrez)NM_001204869 NM_001204870 NM_003882 NM_080838
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WISP1
Cluster EST : UnigeneHs.492974 [ NCBI ]
CGAP (NCI)Hs.492974
Alternative Splicing GalleryENSG00000104415
Gene ExpressionWISP1 [ NCBI-GEO ]   WISP1 [ EBI - ARRAY_EXPRESS ]   WISP1 [ SEEK ]   WISP1 [ MEM ]
Gene Expression Viewer (FireBrowse)WISP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8840
GTEX Portal (Tissue expression)WISP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95388   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95388  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95388
Splice isoforms : SwissVarO95388
PhosPhoSitePlusO95388
Domaine pattern : Prosite (Expaxy)CTCK_1 (PS01185)    CTCK_2 (PS01225)    IGFBP_N_1 (PS00222)    IGFBP_N_2 (PS51323)    TSP1 (PS50092)    VWFC_1 (PS01208)    VWFC_2 (PS50184)   
Domains : Interpro (EBI)Cys_knot_C    Glyco_hormone_CN    Growth_fac_rcpt_    IGFBP-like    IGFBP_CNN    Insulin_GF-bd_Cys-rich_CS    TSP1_rpt    VWF_dom   
Domain families : Pfam (Sanger)Cys_knot (PF00007)    IGFBP (PF00219)    TSP_1 (PF00090)    VWC (PF00093)   
Domain families : Pfam (NCBI)pfam00007    pfam00219    pfam00090    pfam00093   
Domain families : Smart (EMBL)CT (SM00041)  IB (SM00121)  TSP1 (SM00209)  VWC (SM00214)  
Conserved Domain (NCBI)WISP1
DMDM Disease mutations8840
Blocks (Seattle)WISP1
SuperfamilyO95388
Human Protein AtlasENSG00000104415
Peptide AtlasO95388
HPRD16019
IPIIPI00022054   IPI00011455   IPI00552249   IPI00553239   IPI00973364   IPI00553068   
Protein Interaction databases
DIP (DOE-UCLA)O95388
IntAct (EBI)O95388
FunCoupENSG00000104415
BioGRIDWISP1
STRING (EMBL)WISP1
ZODIACWISP1
Ontologies - Pathways
QuickGOO95388
Ontology : AmiGOregulation of cell growth  insulin-like growth factor binding  extracellular space  cytosol  cell adhesion  signal transduction  cell-cell signaling  Wnt signaling pathway  
Ontology : EGO-EBIregulation of cell growth  insulin-like growth factor binding  extracellular space  cytosol  cell adhesion  signal transduction  cell-cell signaling  Wnt signaling pathway  
NDEx NetworkWISP1
Atlas of Cancer Signalling NetworkWISP1
Wikipedia pathwaysWISP1
Orthology - Evolution
OrthoDB8840
GeneTree (enSembl)ENSG00000104415
Phylogenetic Trees/Animal Genes : TreeFamWISP1
HOVERGENO95388
HOGENOMO95388
Homologs : HomoloGeneWISP1
Homology/Alignments : Family Browser (UCSC)WISP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWISP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WISP1
dbVarWISP1
ClinVarWISP1
1000_GenomesWISP1 
Exome Variant ServerWISP1
ExAC (Exome Aggregation Consortium)WISP1 (select the gene name)
Genetic variants : HAPMAP8840
Genomic Variants (DGV)WISP1 [DGVbeta]
DECIPHERWISP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWISP1 
Mutations
ICGC Data PortalWISP1 
TCGA Data PortalWISP1 
Broad Tumor PortalWISP1
OASIS PortalWISP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWISP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWISP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WISP1
DgiDB (Drug Gene Interaction Database)WISP1
DoCM (Curated mutations)WISP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WISP1 (select a term)
intoGenWISP1
Cancer3DWISP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603398   
Orphanet
MedgenWISP1
Genetic Testing Registry WISP1
NextProtO95388 [Medical]
TSGene8840
GENETestsWISP1
Target ValidationWISP1
Huge Navigator WISP1 [HugePedia]
snp3D : Map Gene to Disease8840
BioCentury BCIQWISP1
ClinGenWISP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8840
Chemical/Pharm GKB GenePA37372
Clinical trialWISP1
Miscellaneous
canSAR (ICR)WISP1 (select the gene name)
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWISP1
EVEXWISP1
GoPubMedWISP1
iHOPWISP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:38:21 CEST 2017

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