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WNT5B (Wnt family member 5B)

Identity

Alias (NCBI)-
HGNC (Hugo) WNT5B
HGNC Previous namewingless-type MMTV integration site family, member 5B
LocusID (NCBI) 81029
Atlas_Id 42826
Location 12p13.33  [Link to chromosome band 12p13]
Location_base_pair Starts at 1629231 and ends at 1647212 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADIPOR2 (12p13.33)::WNT5B (12p13.33)CACNA1C (12p13.33)::WNT5B (12p13.33)SEMA4C (2q11.2)::WNT5B (12p13.33)
WNT5B (12p13.33)::HIPK3 (11p13)WNT5B (12p13.33)::NINJ2 (12p13.33)WNT5B (12p13.33)::PPP2R1A (19q13.41)
ADIPOR2 12p13.33::WNT5B 12p13.33CACNA1C 12p13.33::WNT5B 12p13.33SEMA4C 2q11.2::WNT5B 12p13.33
WNT5B 12p13.33::NINJ2 12p13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)WNT5B   16265
Cards
Entrez_Gene (NCBI)WNT5B    Wnt family member 5B
Aliases
GeneCards (Weizmann)WNT5B
Ensembl hg19 (Hinxton)ENSG00000111186 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111186 [Gene_View]  ENSG00000111186 [Sequence]  chr12:1629231-1647212 [Contig_View]  WNT5B [Vega]
ICGC DataPortalENSG00000111186
TCGA cBioPortalWNT5B
AceView (NCBI)WNT5B
Genatlas (Paris)WNT5B
SOURCE (Princeton)WNT5B
Genetics Home Reference (NIH)WNT5B
Genomic and cartography
GoldenPath hg38 (UCSC)WNT5B  -     chr12:1629231-1647212 +  12p13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WNT5B  -     12p13.33   [Description]    (hg19-Feb_2009)
GoldenPathWNT5B - 12p13.33 [CytoView hg19]  WNT5B - 12p13.33 [CytoView hg38]
ImmunoBaseENSG00000111186
Genome Data Viewer NCBIWNT5B [Mapview hg19]  
OMIM606361   
Gene and transcription
Genbank (Entrez)AB060966 AB209228 AK290430 AK294096 AY009399
RefSeq transcript (Entrez)NM_030775 NM_032642
Consensus coding sequences : CCDS (NCBI)WNT5B
Gene ExpressionWNT5B [ NCBI-GEO ]   WNT5B [ EBI - ARRAY_EXPRESS ]   WNT5B [ SEEK ]   WNT5B [ MEM ]
Gene Expression Viewer (FireBrowse)WNT5B [ Firebrowse - Broad ]
GenevisibleExpression of WNT5B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81029
GTEX Portal (Tissue expression)WNT5B
Human Protein AtlasENSG00000111186-WNT5B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1J7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H1J7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H1J7
PhosPhoSitePlusQ9H1J7
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Wnt    Wnt5b    Wnt_C    Wnt_CS   
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
Conserved Domain (NCBI)WNT5B
SuperfamilyQ9H1J7
AlphaFold pdb e-kbQ9H1J7   
Human Protein Atlas [tissue]ENSG00000111186-WNT5B [tissue]
HPRD05899
Protein Interaction databases
DIP (DOE-UCLA)Q9H1J7
IntAct (EBI)Q9H1J7
BioGRIDWNT5B
STRING (EMBL)WNT5B
ZODIACWNT5B
Ontologies - Pathways
QuickGOQ9H1J7
Ontology : AmiGOchondrocyte differentiation  signaling receptor binding  frizzled binding  cytokine activity  extracellular region  extracellular space  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  neuron differentiation  neuron differentiation  positive regulation of cell migration  endocytic vesicle membrane  wound healing  muscle cell differentiation  cell fate commitment  fat cell differentiation  canonical Wnt signaling pathway  collagen-containing extracellular matrix  extracellular exosome  extracellular exosome  lens fiber cell development  cellular response to retinoic acid  positive regulation of convergent extension involved in gastrulation  positive regulation of non-canonical Wnt signaling pathway  
Ontology : EGO-EBIchondrocyte differentiation  signaling receptor binding  frizzled binding  cytokine activity  extracellular region  extracellular space  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  neuron differentiation  neuron differentiation  positive regulation of cell migration  endocytic vesicle membrane  wound healing  muscle cell differentiation  cell fate commitment  fat cell differentiation  canonical Wnt signaling pathway  collagen-containing extracellular matrix  extracellular exosome  extracellular exosome  lens fiber cell development  cellular response to retinoic acid  positive regulation of convergent extension involved in gastrulation  positive regulation of non-canonical Wnt signaling pathway  
Pathways : KEGGKEGG_WNT_SIGNALING    KEGG_HEDGEHOG_SIGNALING    KEGG_MELANOGENESIS    KEGG_PATHWAYS_IN_CANCER    KEGG_BASAL_CELL_CARCINOMA   
NDEx NetworkWNT5B
Atlas of Cancer Signalling NetworkWNT5B
Wikipedia pathwaysWNT5B
Orthology - Evolution
OrthoDB81029
GeneTree (enSembl)ENSG00000111186
Phylogenetic Trees/Animal Genes : TreeFamWNT5B
Homologs : HomoloGeneWNT5B
Homology/Alignments : Family Browser (UCSC)WNT5B
Gene fusions - Rearrangements
Fusion : MitelmanADIPOR2::WNT5B [12p13.33/12p13.33]  
Fusion : MitelmanCACNA1C::WNT5B [12p13.33/12p13.33]  
Fusion : MitelmanSEMA4C::WNT5B [2q11.2/12p13.33]  
Fusion : MitelmanWNT5B::NINJ2 [12p13.33/12p13.33]  
Fusion : QuiverWNT5B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWNT5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WNT5B
dbVarWNT5B
ClinVarWNT5B
MonarchWNT5B
1000_GenomesWNT5B 
Exome Variant ServerWNT5B
GNOMAD BrowserENSG00000111186
Varsome BrowserWNT5B
ACMGWNT5B variants
VarityQ9H1J7
Genomic Variants (DGV)WNT5B [DGVbeta]
DECIPHERWNT5B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWNT5B 
Mutations
ICGC Data PortalWNT5B 
TCGA Data PortalWNT5B 
Broad Tumor PortalWNT5B
OASIS PortalWNT5B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWNT5B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DWNT5B
Mutations and Diseases : HGMDWNT5B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaWNT5B
DgiDB (Drug Gene Interaction Database)WNT5B
DoCM (Curated mutations)WNT5B
CIViC (Clinical Interpretations of Variants in Cancer)WNT5B
Cancer3DWNT5B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606361   
Orphanet
DisGeNETWNT5B
MedgenWNT5B
Genetic Testing Registry WNT5B
NextProtQ9H1J7 [Medical]
GENETestsWNT5B
Target ValidationWNT5B
Huge Navigator WNT5B [HugePedia]
ClinGenWNT5B
Clinical trials, drugs, therapy
MyCancerGenomeWNT5B
Protein Interactions : CTDWNT5B
Pharm GKB GenePA38104
PharosQ9H1J7
Clinical trialWNT5B
Miscellaneous
canSAR (ICR)WNT5B
HarmonizomeWNT5B
ARCHS4WNT5B
DataMed IndexWNT5B
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXWNT5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 13:06:37 CET 2022

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