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WNT5B (wingless-type MMTV integration site family, member 5B)

Identity

Other names-
HGNC (Hugo) WNT5B
LocusID (NCBI) 81029
Atlas_Id 42826
Location 12p13.33
Location_base_pair Starts at 1726222 and ends at 1756377 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)WNT5B   16265
Cards
Entrez_Gene (NCBI)WNT5B  81029  wingless-type MMTV integration site family, member 5B
GeneCards (Weizmann)WNT5B
Ensembl hg19 (Hinxton)ENSG00000111186 [Gene_View]  chr12:1726222-1756377 [Contig_View]  WNT5B [Vega]
Ensembl hg38 (Hinxton)ENSG00000111186 [Gene_View]  chr12:1726222-1756377 [Contig_View]  WNT5B [Vega]
ICGC DataPortalENSG00000111186
TCGA cBioPortalWNT5B
AceView (NCBI)WNT5B
Genatlas (Paris)WNT5B
WikiGenes81029
SOURCE (Princeton)WNT5B
Genomic and cartography
GoldenPath hg19 (UCSC)WNT5B  -     chr12:1726222-1756377 +  12p13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WNT5B  -     12p13.33   [Description]    (hg38-Dec_2013)
EnsemblWNT5B - 12p13.33 [CytoView hg19]  WNT5B - 12p13.33 [CytoView hg38]
Mapping of homologs : NCBIWNT5B [Mapview hg19]  WNT5B [Mapview hg38]
OMIM606361   
Gene and transcription
Genbank (Entrez)AB060966 AB209228 AK290430 AY009399 BC001749
RefSeq transcript (Entrez)NM_030775 NM_032642
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_009759 NW_004929382
Consensus coding sequences : CCDS (NCBI)WNT5B
Cluster EST : UnigeneHs.306051 [ NCBI ]
CGAP (NCI)Hs.306051
Alternative Splicing : Fast-db (Paris)GSHG0006371
Alternative Splicing GalleryENSG00000111186
Gene ExpressionWNT5B [ NCBI-GEO ]     WNT5B [ SEEK ]   WNT5B [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1J7 (Uniprot)
NextProtQ9H1J7  [Medical]
With graphics : InterProQ9H1J7
Splice isoforms : SwissVarQ9H1J7 (Swissvar)
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Wnt    Wnt5b    Wnt_CS   
Related proteins : CluSTrQ9H1J7
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
DMDM Disease mutations81029
Blocks (Seattle)Q9H1J7
Human Protein AtlasENSG00000111186
Peptide AtlasQ9H1J7
HPRD05899
IPIIPI00022223   IPI01011558   IPI00747307   IPI01009461   IPI01016020   
Protein Interaction databases
DIP (DOE-UCLA)Q9H1J7
IntAct (EBI)Q9H1J7
FunCoupENSG00000111186
BioGRIDWNT5B
IntegromeDBWNT5B
STRING (EMBL)WNT5B
Ontologies - Pathways
QuickGOQ9H1J7
Ontology : AmiGOchondrocyte differentiation  receptor binding  frizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  cell surface  Wnt signaling pathway  Wnt signaling pathway  neuron differentiation  neuron differentiation  positive regulation of cell migration  wound healing  cell fate commitment  fat cell differentiation  positive regulation of fat cell differentiation  extracellular exosome  lens fiber cell development  cellular response to retinoic acid  negative regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIchondrocyte differentiation  receptor binding  frizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  cell surface  Wnt signaling pathway  Wnt signaling pathway  neuron differentiation  neuron differentiation  positive regulation of cell migration  wound healing  cell fate commitment  fat cell differentiation  positive regulation of fat cell differentiation  extracellular exosome  lens fiber cell development  cellular response to retinoic acid  negative regulation of canonical Wnt signaling pathway  
Pathways : KEGGWnt signaling pathway    Hedgehog signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
Protein Interaction DatabaseWNT5B
DoCM (Curated mutations)WNT5B
Wikipedia pathwaysWNT5B
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerWNT5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WNT5B
dbVarWNT5B
ClinVarWNT5B
1000_GenomesWNT5B 
Exome Variant ServerWNT5B
SNP (GeneSNP Utah)WNT5B
SNP : HGBaseWNT5B
Genetic variants : HAPMAPWNT5B
Genomic Variants (DGV)WNT5B [DGVbeta]
Mutations
ICGC Data PortalWNT5B 
TCGA Data PortalWNT5B 
Tumor PortalWNT5B
Somatic Mutations in Cancer : COSMICWNT5B 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:1726222-1756377
CONAN: Copy Number AnalysisWNT5B 
Mutations and Diseases : HGMDWNT5B
OMIM606361   
MedgenWNT5B
NextProtQ9H1J7 [Medical]
GENETestsWNT5B
Disease Genetic AssociationWNT5B
Huge Navigator WNT5B [HugePedia]  WNT5B [HugeCancerGEM]
snp3D : Map Gene to Disease81029
DGIdb (Drug Gene Interaction db)WNT5B
General knowledge
Homologs : HomoloGeneWNT5B
Homology/Alignments : Family Browser (UCSC)WNT5B
Phylogenetic Trees/Animal Genes : TreeFamWNT5B
Chemical/Protein Interactions : CTD81029
Chemical/Pharm GKB GenePA38104
Clinical trialWNT5B
Cancer Resource (Charite)ENSG00000111186
Other databases
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
CoreMineWNT5B
GoPubMedWNT5B
iHOPWNT5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 20:20:49 CEST 2015

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