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WNT6 (Wnt family member 6)

Identity

Alias_nameswingless-type MMTV integration site family
Other alias-
HGNC (Hugo) WNT6
LocusID (NCBI) 7475
Atlas_Id 42827
Location 2q35  [Link to chromosome band 2q35]
Location_base_pair Starts at 218859823 and ends at 218874232 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WNT6   12785
Cards
Entrez_Gene (NCBI)WNT6  7475  Wnt family member 6
Aliases
GeneCards (Weizmann)WNT6
Ensembl hg19 (Hinxton)ENSG00000115596 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115596 [Gene_View]  chr2:218859823-218874232 [Contig_View]  WNT6 [Vega]
ICGC DataPortalENSG00000115596
TCGA cBioPortalWNT6
AceView (NCBI)WNT6
Genatlas (Paris)WNT6
WikiGenes7475
SOURCE (Princeton)WNT6
Genetics Home Reference (NIH)WNT6
Genomic and cartography
GoldenPath hg38 (UCSC)WNT6  -     chr2:218859823-218874232 +  2q35   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WNT6  -     2q35   [Description]    (hg19-Feb_2009)
EnsemblWNT6 - 2q35 [CytoView hg19]  WNT6 - 2q35 [CytoView hg38]
Mapping of homologs : NCBIWNT6 [Mapview hg19]  WNT6 [Mapview hg38]
OMIM604663   
Gene and transcription
Genbank (Entrez)AB059570 AK075522 AY009401 BC004329 BT007456
RefSeq transcript (Entrez)NM_006522
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WNT6
Cluster EST : UnigeneHs.29764 [ NCBI ]
CGAP (NCI)Hs.29764
Alternative Splicing GalleryENSG00000115596
Gene ExpressionWNT6 [ NCBI-GEO ]   WNT6 [ EBI - ARRAY_EXPRESS ]   WNT6 [ SEEK ]   WNT6 [ MEM ]
Gene Expression Viewer (FireBrowse)WNT6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7475
GTEX Portal (Tissue expression)WNT6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6F9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6F9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6F9
Splice isoforms : SwissVarQ9Y6F9
PhosPhoSitePlusQ9Y6F9
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Wnt    Wnt6    Wnt_CS   
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
Conserved Domain (NCBI)WNT6
DMDM Disease mutations7475
Blocks (Seattle)WNT6
SuperfamilyQ9Y6F9
Human Protein AtlasENSG00000115596
Peptide AtlasQ9Y6F9
HPRD05233
IPIIPI00002239   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6F9
IntAct (EBI)Q9Y6F9
FunCoupENSG00000115596
BioGRIDWNT6
STRING (EMBL)WNT6
ZODIACWNT6
Ontologies - Pathways
QuickGOQ9Y6F9
Ontology : AmiGObranching involved in ureteric bud morphogenesis  frizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  axis specification  cell surface  positive regulation of gene expression  Wnt signaling pathway  Wnt signaling pathway  neuron differentiation  neuron differentiation  endocytic vesicle membrane  odontogenesis of dentin-containing tooth  cell fate commitment  positive regulation of transcription, DNA-templated  epithelial-mesenchymal cell signaling  cornea development in camera-type eye  extracellular exosome  positive regulation of tooth mineralization  cellular response to retinoic acid  nephron tubule formation  
Ontology : EGO-EBIbranching involved in ureteric bud morphogenesis  frizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  axis specification  cell surface  positive regulation of gene expression  Wnt signaling pathway  Wnt signaling pathway  neuron differentiation  neuron differentiation  endocytic vesicle membrane  odontogenesis of dentin-containing tooth  cell fate commitment  positive regulation of transcription, DNA-templated  epithelial-mesenchymal cell signaling  cornea development in camera-type eye  extracellular exosome  positive regulation of tooth mineralization  cellular response to retinoic acid  nephron tubule formation  
Pathways : KEGGWnt signaling pathway    Hedgehog signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
NDEx NetworkWNT6
Atlas of Cancer Signalling NetworkWNT6
Wikipedia pathwaysWNT6
Orthology - Evolution
OrthoDB7475
GeneTree (enSembl)ENSG00000115596
Phylogenetic Trees/Animal Genes : TreeFamWNT6
HOVERGENQ9Y6F9
HOGENOMQ9Y6F9
Homologs : HomoloGeneWNT6
Homology/Alignments : Family Browser (UCSC)WNT6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWNT6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WNT6
dbVarWNT6
ClinVarWNT6
1000_GenomesWNT6 
Exome Variant ServerWNT6
ExAC (Exome Aggregation Consortium)WNT6 (select the gene name)
Genetic variants : HAPMAP7475
Genomic Variants (DGV)WNT6 [DGVbeta]
DECIPHERWNT6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWNT6 
Mutations
ICGC Data PortalWNT6 
TCGA Data PortalWNT6 
Broad Tumor PortalWNT6
OASIS PortalWNT6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWNT6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWNT6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WNT6
DgiDB (Drug Gene Interaction Database)WNT6
DoCM (Curated mutations)WNT6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WNT6 (select a term)
intoGenWNT6
Cancer3DWNT6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604663   
Orphanet
MedgenWNT6
Genetic Testing Registry WNT6
NextProtQ9Y6F9 [Medical]
TSGene7475
GENETestsWNT6
Target ValidationWNT6
Huge Navigator WNT6 [HugePedia]
snp3D : Map Gene to Disease7475
BioCentury BCIQWNT6
ClinGenWNT6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7475
Chemical/Pharm GKB GenePA37386
Clinical trialWNT6
Miscellaneous
canSAR (ICR)WNT6 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWNT6
EVEXWNT6
GoPubMedWNT6
iHOPWNT6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:38:24 CEST 2017

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