Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WNT7A (Wnt family member 7A)

Identity

HGNC (Hugo) WNT7A
LocusID (NCBI) 7476
Atlas_Id 42828
Location 3p25.1
Location_base_pair Starts at 13860082 and ends at 13921618 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CUX1 (7q22.1) / WNT7A (3p25.1)IQSEC1 (3p25.2) / WNT7A (3p25.1)NAP1L1 (12q21.2) / WNT7A (3p25.1)
NUP210 (3p25.1) / WNT7A (3p25.1)SFMBT1 (3p21.1) / WNT7A (3p25.1)UBE2E1 (3p24.3) / WNT7A (3p25.1)
IQSEC1 3p25.2 / WNT7A 3p25.1SFMBT1 3p21.1 / WNT7A 3p25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WNT7A   12786
Cards
Entrez_Gene (NCBI)WNT7A  7476  Wnt family member 7A
GeneCards (Weizmann)WNT7A
Ensembl hg19 (Hinxton)ENSG00000154764 [Gene_View]  chr3:13860082-13921618 [Contig_View]  WNT7A [Vega]
Ensembl hg38 (Hinxton)ENSG00000154764 [Gene_View]  chr3:13860082-13921618 [Contig_View]  WNT7A [Vega]
ICGC DataPortalENSG00000154764
TCGA cBioPortalWNT7A
AceView (NCBI)WNT7A
Genatlas (Paris)WNT7A
WikiGenes7476
SOURCE (Princeton)WNT7A
Genomic and cartography
GoldenPath hg19 (UCSC)WNT7A  -     chr3:13860082-13921618 -  3p25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WNT7A  -     3p25.1   [Description]    (hg38-Dec_2013)
EnsemblWNT7A - 3p25.1 [CytoView hg19]  WNT7A - 3p25.1 [CytoView hg38]
Mapping of homologs : NCBIWNT7A [Mapview hg19]  WNT7A [Mapview hg38]
OMIM228930   276820   601570   
Gene and transcription
Genbank (Entrez)BC008811 D83175 DQ893023 DQ896267 U53476
RefSeq transcript (Entrez)NM_004625
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_008088 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)WNT7A
Cluster EST : UnigeneHs.72290 [ NCBI ]
CGAP (NCI)Hs.72290
Alternative Splicing : Fast-db (Paris)GSHG0021535
Alternative Splicing GalleryENSG00000154764
Gene ExpressionWNT7A [ NCBI-GEO ]   WNT7A [ EBI - ARRAY_EXPRESS ]   WNT7A [ SEEK ]   WNT7A [ MEM ]
Gene Expression Viewer (FireBrowse)WNT7A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)7476
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00755 (Uniprot)
NextProtO00755  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00755
Splice isoforms : SwissVarO00755 (Swissvar)
PhosPhoSitePlusO00755
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Wnt    Wnt7    Wnt_CS   
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
DMDM Disease mutations7476
Blocks (Seattle)WNT7A
PDB (SRS)4UZQ   
PDB (PDBSum)4UZQ   
PDB (IMB)4UZQ   
PDB (RSDB)4UZQ   
Structural Biology KnowledgeBase4UZQ   
SCOP (Structural Classification of Proteins)4UZQ   
CATH (Classification of proteins structures)4UZQ   
SuperfamilyO00755
Human Protein AtlasENSG00000154764
Peptide AtlasO00755
HPRD03341
IPIIPI00012990   
Protein Interaction databases
DIP (DOE-UCLA)O00755
IntAct (EBI)O00755
FunCoupENSG00000154764
BioGRIDWNT7A
STRING (EMBL)WNT7A
ZODIACWNT7A
Ontologies - Pathways
QuickGOO00755
Ontology : AmiGOembryonic axis specification  cartilage condensation  angiogenesis  chondrocyte differentiation  receptor binding  frizzled binding  cytokine activity  protein binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  cytosol  plasma membrane  neurotransmitter secretion  axonogenesis  synapse assembly  sex differentiation  asymmetric protein localization  dorsal/ventral pattern formation  cell surface  positive regulation of endothelial cell migration  skeletal muscle satellite cell activation  skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration  Wnt signaling pathway  cerebellar granule cell differentiation  cell proliferation in forebrain  central nervous system vasculogenesis  establishment of cell polarity  endocytic vesicle membrane  regulation of axon diameter  response to estradiol  somatic stem cell population maintenance  embryonic forelimb morphogenesis  embryonic hindlimb morphogenesis  non-canonical Wnt signaling pathway  Wnt signaling pathway involved in wound healing, spreading of epidermal cells  synaptic vesicle recycling  embryonic digit morphogenesis  negative regulation of apoptotic process  cell fate commitment  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  positive regulation of JNK cascade  receptor agonist activity  receptor agonist activity  somatic stem cell division  stem cell development  negative regulation of neurogenesis  positive regulation of synapse assembly  palate development  positive regulation of epithelial cell proliferation involved in wound healing  oviduct development  canonical Wnt signaling pathway  dendritic spine morphogenesis  uterus morphogenesis  extracellular exosome  lens fiber cell development  cellular response to transforming growth factor beta stimulus  positive regulation of canonical Wnt signaling pathway  presynapse  presynapse  positive regulation of protein localization to synapse  excitatory synapse assembly  positive regulation of excitatory synapse assembly  positive regulation of excitatory postsynaptic potential  
Ontology : EGO-EBIembryonic axis specification  cartilage condensation  angiogenesis  chondrocyte differentiation  receptor binding  frizzled binding  cytokine activity  protein binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  cytosol  plasma membrane  neurotransmitter secretion  axonogenesis  synapse assembly  sex differentiation  asymmetric protein localization  dorsal/ventral pattern formation  cell surface  positive regulation of endothelial cell migration  skeletal muscle satellite cell activation  skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration  Wnt signaling pathway  cerebellar granule cell differentiation  cell proliferation in forebrain  central nervous system vasculogenesis  establishment of cell polarity  endocytic vesicle membrane  regulation of axon diameter  response to estradiol  somatic stem cell population maintenance  embryonic forelimb morphogenesis  embryonic hindlimb morphogenesis  non-canonical Wnt signaling pathway  Wnt signaling pathway involved in wound healing, spreading of epidermal cells  synaptic vesicle recycling  embryonic digit morphogenesis  negative regulation of apoptotic process  cell fate commitment  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  positive regulation of JNK cascade  receptor agonist activity  receptor agonist activity  somatic stem cell division  stem cell development  negative regulation of neurogenesis  positive regulation of synapse assembly  palate development  positive regulation of epithelial cell proliferation involved in wound healing  oviduct development  canonical Wnt signaling pathway  dendritic spine morphogenesis  uterus morphogenesis  extracellular exosome  lens fiber cell development  cellular response to transforming growth factor beta stimulus  positive regulation of canonical Wnt signaling pathway  presynapse  presynapse  positive regulation of protein localization to synapse  excitatory synapse assembly  positive regulation of excitatory synapse assembly  positive regulation of excitatory postsynaptic potential  
Pathways : KEGGWnt signaling pathway    Hedgehog signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
NDEx Network
Atlas of Cancer Signalling NetworkWNT7A
Wikipedia pathwaysWNT7A
Orthology - Evolution
OrthoDB7476
GeneTree (enSembl)ENSG00000154764
Phylogenetic Trees/Animal Genes : TreeFamWNT7A
Homologs : HomoloGeneWNT7A
Homology/Alignments : Family Browser (UCSC)WNT7A
Gene fusions - Rearrangements
Fusion: TCGAIQSEC1 3p25.2 WNT7A 3p25.1 BLCA
Fusion: TCGASFMBT1 3p21.1 WNT7A 3p25.1 LUAD
Polymorphisms : SNP, variants
NCBI Variation ViewerWNT7A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WNT7A
dbVarWNT7A
ClinVarWNT7A
1000_GenomesWNT7A 
Exome Variant ServerWNT7A
ExAC (Exome Aggregation Consortium)WNT7A (select the gene name)
SNP (GeneSNP Utah)WNT7A
SNP : HGBaseWNT7A
Genetic variants : HAPMAPWNT7A
Genomic Variants (DGV)WNT7A [DGVbeta]
Mutations
ICGC Data PortalWNT7A 
TCGA Data PortalWNT7A 
Broad Tumor PortalWNT7A
OASIS PortalWNT7A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWNT7A 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WNT7A
DgiDB (Drug Gene Interaction Database)WNT7A
DoCM (Curated mutations)WNT7A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WNT7A (select a term)
intoGenWNT7A
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:13860082-13921618
CONAN: Copy Number AnalysisWNT7A 
Mutations and Diseases : HGMDWNT7A
OMIM228930    276820    601570   
MedgenWNT7A
Genetic Testing Registry WNT7A
NextProtO00755 [Medical]
TSGene7476
GENETestsWNT7A
Huge Navigator WNT7A [HugePedia]  WNT7A [HugeCancerGEM]
snp3D : Map Gene to Disease7476
BioCentury BCIQWNT7A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7476
Chemical/Pharm GKB GenePA37387
Clinical trialWNT7A
Miscellaneous
canSAR (ICR)WNT7A (select the gene name)
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWNT7A
GoPubMedWNT7A
iHOPWNT7A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Apr 16 18:10:06 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.