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WNT7A (wingless-type MMTV integration site family, member 7A)

Identity

Other names-
HGNC (Hugo) WNT7A
LocusID (NCBI) 7476
Location 3p25.1
Location_base_pair Starts at 13860082 and ends at 13921618 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)WNT7A   12786
Cards
Entrez_Gene (NCBI)WNT7A  7476  wingless-type MMTV integration site family, member 7A
GeneCards (Weizmann)WNT7A
Ensembl (Hinxton) [Gene_View]  chr3:13860082-13921618 [Contig_View]  WNT7A [Vega]
AceView (NCBI)WNT7A
Genatlas (Paris)WNT7A
WikiGenes7476
SOURCE (Princeton)NM_004625
Genomic and cartography
GoldenPath (UCSC)WNT7A  -  3p25.1   chr3:13860082-13921618 -  3p25.1   [Description]    (hg19-Feb_2009)
EnsemblWNT7A - 3p25.1 [CytoView]
Mapping of homologs : NCBIWNT7A [Mapview]
OMIM228930   276820   601570   
Gene and transcription
Genbank (Entrez)BC008811 D83175 DQ893023 DQ896267 U53476
RefSeq transcript (Entrez)NM_004625
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_008088 NT_022517 NW_001838877 NW_004929309
Consensus coding sequences : CCDS (NCBI)WNT7A
Cluster EST : UnigeneHs.72290 [ NCBI ]
CGAP (NCI)Hs.72290
Alternative Splicing : Fast-db (Paris)GSHG0021535
Gene ExpressionWNT7A [ NCBI-GEO ]     WNT7A [ SEEK ]   WNT7A [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00755 (Uniprot)
NextProtO00755  [Medical]
With graphics : InterProO00755
Splice isoforms : SwissVarO00755 (Swissvar)
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Wnt    Wnt7    Wnt_CS   
Related proteins : CluSTrO00755
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
DMDM Disease mutations7476
Blocks (Seattle)O00755
Peptide AtlasO00755
HPRD03341
IPIIPI00012990   
Protein Interaction databases
DIP (DOE-UCLA)O00755
IntAct (EBI)O00755
BioGRIDWNT7A
IntegromeDBWNT7A
STRING (EMBL)WNT7A
Ontologies - Pathways
QuickGOO00755
Ontology : AmiGOembryonic axis specification  cartilage condensation  chondrocyte differentiation  receptor binding  frizzled binding  cytokine activity  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  neurotransmitter secretion  sex differentiation  asymmetric protein localization  dorsal/ventral pattern formation  cell surface  skeletal muscle satellite cell activation  skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration  cerebellar granule cell differentiation  cell proliferation in forebrain  central nervous system vasculogenesis  establishment of cell polarity  neuron differentiation  regulation of axon diameter  response to estradiol  embryonic forelimb morphogenesis  embryonic hindlimb morphogenesis  non-canonical Wnt signaling pathway  Wnt signaling pathway involved in wound healing, spreading of epidermal cells  embryonic digit morphogenesis  negative regulation of apoptotic process  cell fate commitment  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  positive regulation of JNK cascade  receptor agonist activity  receptor agonist activity  somatic stem cell division  stem cell development  negative regulation of neurogenesis  synapse organization  positive regulation of synapse assembly  palate development  positive regulation of epithelial cell proliferation involved in wound healing  oviduct development  canonical Wnt signaling pathway  uterus morphogenesis  lens fiber cell development  cellular response to transforming growth factor beta stimulus  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIembryonic axis specification  cartilage condensation  chondrocyte differentiation  receptor binding  frizzled binding  cytokine activity  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  neurotransmitter secretion  sex differentiation  asymmetric protein localization  dorsal/ventral pattern formation  cell surface  skeletal muscle satellite cell activation  skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration  cerebellar granule cell differentiation  cell proliferation in forebrain  central nervous system vasculogenesis  establishment of cell polarity  neuron differentiation  regulation of axon diameter  response to estradiol  embryonic forelimb morphogenesis  embryonic hindlimb morphogenesis  non-canonical Wnt signaling pathway  Wnt signaling pathway involved in wound healing, spreading of epidermal cells  embryonic digit morphogenesis  negative regulation of apoptotic process  cell fate commitment  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  positive regulation of JNK cascade  receptor agonist activity  receptor agonist activity  somatic stem cell division  stem cell development  negative regulation of neurogenesis  synapse organization  positive regulation of synapse assembly  palate development  positive regulation of epithelial cell proliferation involved in wound healing  oviduct development  canonical Wnt signaling pathway  uterus morphogenesis  lens fiber cell development  cellular response to transforming growth factor beta stimulus  positive regulation of canonical Wnt signaling pathway  
Pathways : KEGGWnt signaling pathway    Hedgehog signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
Protein Interaction DatabaseWNT7A
Wikipedia pathwaysWNT7A
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)WNT7A
SNP (GeneSNP Utah)WNT7A
SNP : HGBaseWNT7A
Genetic variants : HAPMAPWNT7A
1000_GenomesWNT7A 
CONAN: Copy Number AnalysisWNT7A 
Somatic Mutations in Cancer : COSMICWNT7A 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)3:13860082-13921618
Mutations and Diseases : HGMDWNT7A
OMIM228930    276820    601570   
MedgenWNT7A
GENETestsWNT7A
Disease Genetic AssociationWNT7A
Huge Navigator WNT7A [HugePedia]  WNT7A [HugeCancerGEM]
Genomic VariantsWNT7A  WNT7A [DGVbeta]
Exome VariantWNT7A
dbVarWNT7A
ClinVarWNT7A
snp3D : Map Gene to Disease7476
General knowledge
Homologs : HomoloGeneWNT7A
Homology/Alignments : Family Browser (UCSC)WNT7A
Phylogenetic Trees/Animal Genes : TreeFamWNT7A
Chemical/Protein Interactions : CTD7476
Chemical/Pharm GKB GenePA37387
Clinical trialWNT7A
Other databases
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
CoreMineWNT7A
GoPubMedWNT7A
iHOPWNT7A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 18:05:48 CET 2014

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