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WNT7B (wingless-type MMTV integration site family, member 7B)

Identity

Other names-
HGNC (Hugo) WNT7B
LocusID (NCBI) 7477
Location 22q13.31
Location_base_pair Starts at 46316248 and ends at 46373008 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)WNT7B   12787
Cards
Entrez_Gene (NCBI)WNT7B  7477  wingless-type MMTV integration site family, member 7B
GeneCards (Weizmann)WNT7B
Ensembl (Hinxton)ENSG00000188064 [Gene_View]  chr22:46316248-46373008 [Contig_View]  WNT7B [Vega]
ICGC DataPortalENSG00000188064
cBioPortalWNT7B
AceView (NCBI)WNT7B
Genatlas (Paris)WNT7B
WikiGenes7477
SOURCE (Princeton)NM_058238
Genomic and cartography
GoldenPath (UCSC)WNT7B  -  22q13.31   chr22:46316248-46373008 -  22q13.31   [Description]    (hg19-Feb_2009)
EnsemblWNT7B - 22q13.31 [CytoView]
Mapping of homologs : NCBIWNT7B [Mapview]
OMIM601967   
Gene and transcription
Genbank (Entrez)AB062766 AF416743 AK123019 AK289526 BC034923
RefSeq transcript (Entrez)NM_058238
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838751 NW_004929430
Consensus coding sequences : CCDS (NCBI)WNT7B
Cluster EST : UnigeneHs.512714 [ NCBI ]
CGAP (NCI)Hs.512714
Alternative Splicing : Fast-db (Paris)GSHG0020477
Alternative Splicing GalleryENSG00000188064
Gene ExpressionWNT7B [ NCBI-GEO ]     WNT7B [ SEEK ]   WNT7B [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP56706 (Uniprot)
NextProtP56706  [Medical]
With graphics : InterProP56706
Splice isoforms : SwissVarP56706 (Swissvar)
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Wnt [organisation]   Wnt7 [organisation]   Wnt_CS [organisation]  
Related proteins : CluSTrP56706
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
DMDM Disease mutations7477
Blocks (Seattle)P56706
Human Protein AtlasENSG00000188064 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP56706
HPRD03573
IPIIPI00011031   IPI00917719   IPI00876998   IPI00917468   IPI00917295   
Protein Interaction databases
DIP (DOE-UCLA)P56706
IntAct (EBI)P56706
FunCoupENSG00000188064
BioGRIDWNT7B
InParanoidP56706
Interologous Interaction database P56706
IntegromeDBWNT7B
STRING (EMBL)WNT7B
Ontologies - Pathways
Ontology : AmiGOin utero embryonic development  metanephros morphogenesis  frizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  activation of JUN kinase activity  positive regulation of cell proliferation  positive regulation of gene expression  Wnt signaling pathway  Wnt signaling pathway  establishment or maintenance of polarity of embryonic epithelium  forebrain regionalization  central nervous system vasculogenesis  neuron differentiation  lung development  oxygen homeostasis  regulation of cell projection size  odontogenesis of dentin-containing tooth  homeostatic process  cellular metabolic process  cell fate commitment  positive regulation of osteoblast differentiation  negative regulation of smoothened signaling pathway  positive regulation of JNK cascade  fibroblast proliferation  embryonic organ development  neuron projection morphogenesis  synapse organization  smooth muscle cell differentiation  response to glucocorticoid  anatomical structure regression  canonical Wnt signaling pathway  lung morphogenesis  lung epithelium development  lobar bronchus development  lung-associated mesenchyme development  trachea cartilage morphogenesis  developmental growth involved in morphogenesis  embryonic placenta morphogenesis  chorio-allantoic fusion  mammary gland epithelium development  lens fiber cell development  cellular response to retinoic acid  renal inner medulla development  renal outer medulla development  outer medullary collecting duct development  inner medullary collecting duct development  stem cell proliferation  metanephric collecting duct development  metanephric epithelium development  metanephric loop of Henle development  apoptotic process involved in patterning of blood vessels  
Ontology : EGO-EBIin utero embryonic development  metanephros morphogenesis  frizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  activation of JUN kinase activity  positive regulation of cell proliferation  positive regulation of gene expression  Wnt signaling pathway  Wnt signaling pathway  establishment or maintenance of polarity of embryonic epithelium  forebrain regionalization  central nervous system vasculogenesis  neuron differentiation  lung development  oxygen homeostasis  regulation of cell projection size  odontogenesis of dentin-containing tooth  homeostatic process  cellular metabolic process  cell fate commitment  positive regulation of osteoblast differentiation  negative regulation of smoothened signaling pathway  positive regulation of JNK cascade  fibroblast proliferation  embryonic organ development  neuron projection morphogenesis  synapse organization  smooth muscle cell differentiation  response to glucocorticoid  anatomical structure regression  canonical Wnt signaling pathway  lung morphogenesis  lung epithelium development  lobar bronchus development  lung-associated mesenchyme development  trachea cartilage morphogenesis  developmental growth involved in morphogenesis  embryonic placenta morphogenesis  chorio-allantoic fusion  mammary gland epithelium development  lens fiber cell development  cellular response to retinoic acid  renal inner medulla development  renal outer medulla development  outer medullary collecting duct development  inner medullary collecting duct development  stem cell proliferation  metanephric collecting duct development  metanephric epithelium development  metanephric loop of Henle development  apoptotic process involved in patterning of blood vessels  
Pathways : KEGGWnt signaling pathway    Hedgehog signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
Protein Interaction DatabaseWNT7B
Wikipedia pathwaysWNT7B
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)WNT7B
snp3D : Map Gene to Disease7477
SNP (GeneSNP Utah)WNT7B
SNP : HGBaseWNT7B
Genetic variants : HAPMAPWNT7B
Exome VariantWNT7B
1000_GenomesWNT7B 
ICGC programENSG00000188064 
Somatic Mutations in Cancer : COSMICWNT7B 
CONAN: Copy Number AnalysisWNT7B 
Mutations and Diseases : HGMDWNT7B
Genomic VariantsWNT7B  WNT7B [DGVbeta]
dbVarWNT7B
ClinVarWNT7B
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM601967   
MedgenWNT7B
GENETestsWNT7B
Disease Genetic AssociationWNT7B
Huge Navigator WNT7B [HugePedia]  WNT7B [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneWNT7B
Homology/Alignments : Family Browser (UCSC)WNT7B
Phylogenetic Trees/Animal Genes : TreeFamWNT7B
Chemical/Protein Interactions : CTD7477
Chemical/Pharm GKB GenePA37388
Clinical trialWNT7B
Cancer Resource (Charite)ENSG00000188064
Other databases
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
CoreMineWNT7B
iHOPWNT7B
OncoSearchWNT7B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jul 26 14:52:18 CEST 2014

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