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WNT7B (Wnt family member 7B)

Identity

Other names-
HGNC (Hugo) WNT7B
LocusID (NCBI) 7477
Atlas_Id 42829
Location 22q13.31
Location_base_pair Starts at 46316248 and ends at 46373008 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PSMC4 (19q13.2) / WNT7B (22q13.31)WNT7B (22q13.31) / DGCR8 (22q11.21)WNT7B 22q13.31 / DGCR8 22q11.21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WNT7B   12787
Cards
Entrez_Gene (NCBI)WNT7B  7477  Wnt family member 7B
Aliases
GeneCards (Weizmann)WNT7B
Ensembl hg19 (Hinxton)ENSG00000188064 [Gene_View]  chr22:46316248-46373008 [Contig_View]  WNT7B [Vega]
Ensembl hg38 (Hinxton)ENSG00000188064 [Gene_View]  chr22:46316248-46373008 [Contig_View]  WNT7B [Vega]
ICGC DataPortalENSG00000188064
TCGA cBioPortalWNT7B
AceView (NCBI)WNT7B
Genatlas (Paris)WNT7B
WikiGenes7477
SOURCE (Princeton)WNT7B
Genomic and cartography
GoldenPath hg19 (UCSC)WNT7B  -     chr22:46316248-46373008 -  22q13.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WNT7B  -     22q13.31   [Description]    (hg38-Dec_2013)
EnsemblWNT7B - 22q13.31 [CytoView hg19]  WNT7B - 22q13.31 [CytoView hg38]
Mapping of homologs : NCBIWNT7B [Mapview hg19]  WNT7B [Mapview hg38]
OMIM601967   
Gene and transcription
Genbank (Entrez)AB062766 AF416743 AK123019 AK289526 BC034923
RefSeq transcript (Entrez)NM_058238
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)WNT7B
Cluster EST : UnigeneHs.512714 [ NCBI ]
CGAP (NCI)Hs.512714
Alternative Splicing GalleryENSG00000188064
Gene ExpressionWNT7B [ NCBI-GEO ]   WNT7B [ EBI - ARRAY_EXPRESS ]   WNT7B [ SEEK ]   WNT7B [ MEM ]
Gene Expression Viewer (FireBrowse)WNT7B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7477
GTEX Portal (Tissue expression)WNT7B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP56706 (Uniprot)
NextProtP56706  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP56706
Splice isoforms : SwissVarP56706 (Swissvar)
PhosPhoSitePlusP56706
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Wnt    Wnt7    Wnt_CS   
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
DMDM Disease mutations7477
Blocks (Seattle)WNT7B
SuperfamilyP56706
Human Protein AtlasENSG00000188064
Peptide AtlasP56706
HPRD03573
IPIIPI00011031   IPI00917719   IPI00876998   IPI00917468   IPI00917295   
Protein Interaction databases
DIP (DOE-UCLA)P56706
IntAct (EBI)P56706
FunCoupENSG00000188064
BioGRIDWNT7B
STRING (EMBL)WNT7B
ZODIACWNT7B
Ontologies - Pathways
QuickGOP56706
Ontology : AmiGOin utero embryonic development  metanephros morphogenesis  frizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  Wnt signaling pathway  Wnt signaling pathway  Wnt signaling pathway  establishment or maintenance of polarity of embryonic epithelium  forebrain regionalization  central nervous system vasculogenesis  neuron differentiation  lung development  endocytic vesicle membrane  oxygen homeostasis  homeostatic process  cellular metabolic process  cell fate commitment  positive regulation of osteoblast differentiation  fibroblast proliferation  embryonic organ development  synapse organization  canonical Wnt signaling pathway  lung morphogenesis  lung epithelium development  lobar bronchus development  trachea cartilage morphogenesis  developmental growth involved in morphogenesis  embryonic placenta morphogenesis  chorio-allantoic fusion  mammary gland epithelium development  extracellular exosome  lens fiber cell development  cellular response to retinoic acid  renal inner medulla development  renal outer medulla development  outer medullary collecting duct development  inner medullary collecting duct development  stem cell proliferation  metanephric collecting duct development  metanephric epithelium development  metanephric loop of Henle development  
Ontology : EGO-EBIin utero embryonic development  metanephros morphogenesis  frizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  endoplasmic reticulum lumen  Golgi lumen  plasma membrane  Wnt signaling pathway  Wnt signaling pathway  Wnt signaling pathway  establishment or maintenance of polarity of embryonic epithelium  forebrain regionalization  central nervous system vasculogenesis  neuron differentiation  lung development  endocytic vesicle membrane  oxygen homeostasis  homeostatic process  cellular metabolic process  cell fate commitment  positive regulation of osteoblast differentiation  fibroblast proliferation  embryonic organ development  synapse organization  canonical Wnt signaling pathway  lung morphogenesis  lung epithelium development  lobar bronchus development  trachea cartilage morphogenesis  developmental growth involved in morphogenesis  embryonic placenta morphogenesis  chorio-allantoic fusion  mammary gland epithelium development  extracellular exosome  lens fiber cell development  cellular response to retinoic acid  renal inner medulla development  renal outer medulla development  outer medullary collecting duct development  inner medullary collecting duct development  stem cell proliferation  metanephric collecting duct development  metanephric epithelium development  metanephric loop of Henle development  
Pathways : KEGGWnt signaling pathway    Hedgehog signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
NDEx Network
Atlas of Cancer Signalling NetworkWNT7B
Wikipedia pathwaysWNT7B
Orthology - Evolution
OrthoDB7477
GeneTree (enSembl)ENSG00000188064
Phylogenetic Trees/Animal Genes : TreeFamWNT7B
Homologs : HomoloGeneWNT7B
Homology/Alignments : Family Browser (UCSC)WNT7B
Gene fusions - Rearrangements
Fusion: TCGAWNT7B 22q13.31 DGCR8 22q11.21 LUAD
Polymorphisms : SNP, variants
NCBI Variation ViewerWNT7B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WNT7B
dbVarWNT7B
ClinVarWNT7B
1000_GenomesWNT7B 
Exome Variant ServerWNT7B
ExAC (Exome Aggregation Consortium)WNT7B (select the gene name)
Genetic variants : HAPMAP7477
Genomic Variants (DGV)WNT7B [DGVbeta]
Mutations
ICGC Data PortalWNT7B 
TCGA Data PortalWNT7B 
Broad Tumor PortalWNT7B
OASIS PortalWNT7B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWNT7B 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WNT7B
DgiDB (Drug Gene Interaction Database)WNT7B
DoCM (Curated mutations)WNT7B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WNT7B (select a term)
intoGenWNT7B
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)22:46316248-46373008  ENSG00000188064
CONAN: Copy Number AnalysisWNT7B 
Mutations and Diseases : HGMDWNT7B
OMIM601967   
MedgenWNT7B
Genetic Testing Registry WNT7B
NextProtP56706 [Medical]
TSGene7477
GENETestsWNT7B
Huge Navigator WNT7B [HugePedia]
snp3D : Map Gene to Disease7477
BioCentury BCIQWNT7B
ClinGenWNT7B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7477
Chemical/Pharm GKB GenePA37388
Clinical trialWNT7B
Miscellaneous
canSAR (ICR)WNT7B (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWNT7B
EVEXWNT7B
GoPubMedWNT7B
iHOPWNT7B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 11:27:33 CEST 2016

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