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WNT8A (wingless-type MMTV integration site family, member 8A)

Identity

Other namesWNT8D
HGNC (Hugo) WNT8A
LocusID (NCBI) 7478
Location 5q31.2
Location_base_pair Starts at 137419774 and ends at 137427199 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)WNT8A   12788
Entrez_Gene (NCBI)WNT8A  7478  wingless-type MMTV integration site family, member 8A
Cards
GeneCards (Weizmann)WNT8A
Ensembl (Hinxton)ENSG00000061492 [Gene_View]  chr5:137419774-137427199 [Contig_View]  WNT8A [Vega]
AceView (NCBI)WNT8A
Genatlas (Paris)WNT8A
SOURCE (Stanford)NM_031933 NM_058244
Genomic and cartography
GoldenPath (UCSC)WNT8A  -  5q31.2   chr5:137419774-137427199 +  5q31.2   [Description]    (hg19-Feb_2009)
EnsemblWNT8A - 5q31.2 [CytoView]
Mapping of homologs : NCBIWNT8A [Mapview]
OMIM606360   
Gene and transcription
Genbank (Entrez)AB057725 AY009402 BC144001 BC144497 BC156844
RefSeq transcript (SRS)NM_031933 NM_058244
RefSeq transcript (Entrez)NM_031933 NM_058244
RefSeq genomic (SRS)AC_000137 NC_000005 NC_018916 NT_034772 NW_001838952 NW_004078024
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NT_034772 NW_001838952 NW_004078024
Consensus coding sequences : CCDS (NCBI)WNT8A
Cluster EST : UnigeneHs.591274 [ SRS ] Hs.591274 [ NCBI ]
CGAP (NCI)Hs.591274
Alternative Splicing : Fast-db (Paris)GSHG0024266
Alternative Splicing GalleryENSG00000061492
Gene ExpressionWNT8A [ NCBI-GEO ]   WNT8A [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1J5 (SRS) Q9H1J5 (Uniprot)
NextProtQ9H1J5
With graphics : InterProQ9H1J5
Splice isoforms : SwissVarQ9H1J5(Swissvar)
Domaine pattern : Prosite (SRS)WNT1 (PS00246)   
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (SRS)Wnt    Wnt8    Wnt_CS   
Domains : Interpro (EBI)Wnt    Wnt8    Wnt_CS   
Related proteins : CluSTrQ9H1J5
Domain families : Pfam (SRS)wnt (PF00110)   
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
DMDM7478
Blocks (Seattle)Q9H1J5
Human Protein AtlasENSG00000061492
HPRD05898
IPIIPI00926615   IPI00022222   IPI00964621   IPI00967684   
Protein Interaction databases
DIP (DOE-UCLA)Q9H1J5
IntAct (EBI)Q9H1J5
FunCoupENSG00000061492
REACTOMEWNT8A
Protein Interaction Database7478
BioGRIDWNT8A
InParanoidQ9H1J5
Interologous Interaction database Q9H1J5
IntegromeDBWNT8A
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)WNT8A
SNP (GeneSNP Utah)WNT8A
SNP : HGBaseWNT8A
Genetic variants : HAPMAPWNT8A
Somatic Mutations in Cancer : COSMICWNT8A 
CONAN: Copy Number AnalysisWNT8A 
Mutations and Diseases : HGMDWNT8A
OMIM606360   
GENETests606360   
Disease Genetic AssociationWNT8A
Huge Navigator WNT8A [HugePedia]  WNT8A [HugeCancerGEM]
Genomic VariantsWNT8A  WNT8A [DGVbeta]
snp3D : Map Gene to Disease7478
General knowledge
Homologs : HomoloGeneWNT8A
Homology/Alignments : Family Browser (UCSC)WNT8A
Phylogenetic Trees/Animal Genes : TreeFamWNT8A
Chemical/Protein Interactions : CTD7478
Chemical/Pharm GKB GenePA37389
Clinical trialWNT8A
Cancer Resource (Charite)ENSG00000061492
Ontology : AmiGOeye development  G-protein coupled receptor binding  mesodermal cell fate commitment  somitogenesis  frizzled binding  proteinaceous extracellular matrix  extracellular space  extracellular space  plasma membrane  ectoderm development  endoderm development  polarity specification of anterior/posterior axis  dorsal/ventral pattern formation  polarity specification of proximal/distal axis  neural crest cell fate commitment  spinal cord anterior/posterior patterning  negative regulation of Wnt receptor signaling pathway  hindbrain development  notochord development  response to retinoic acid  regulation of protein localization  brain segmentation  cell migration involved in gastrulation  regulation of transcription involved in anterior/posterior axis specification  canonical Wnt receptor signaling pathway involved in neural crest cell differentiation  positive regulation of fibroblast growth factor receptor signaling pathway  receptor agonist activity  establishment of organ orientation  palate development  canonical Wnt receptor signaling pathway  canonical Wnt receptor signaling pathway  canonical Wnt receptor signaling pathway  neural plate pattern specification  canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment  
Ontology : EGO-EBIeye development  G-protein coupled receptor binding  mesodermal cell fate commitment  somitogenesis  frizzled binding  proteinaceous extracellular matrix  extracellular space  extracellular space  plasma membrane  ectoderm development  endoderm development  polarity specification of anterior/posterior axis  dorsal/ventral pattern formation  polarity specification of proximal/distal axis  neural crest cell fate commitment  spinal cord anterior/posterior patterning  negative regulation of Wnt receptor signaling pathway  hindbrain development  notochord development  response to retinoic acid  regulation of protein localization  brain segmentation  cell migration involved in gastrulation  regulation of transcription involved in anterior/posterior axis specification  canonical Wnt receptor signaling pathway involved in neural crest cell differentiation  positive regulation of fibroblast growth factor receptor signaling pathway  receptor agonist activity  establishment of organ orientation  palate development  canonical Wnt receptor signaling pathway  canonical Wnt receptor signaling pathway  canonical Wnt receptor signaling pathway  neural plate pattern specification  canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment  
Pathways : BIOCARTAWnt/LRP6 Signalling [Genes]   
Pathways : KEGGHedgehog signaling pathwayWnt signaling pathway
Other databases
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
PubGeneWNT8A
iHOPWNT8A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:41:10 CEST 2013
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