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WNT8B (wingless-type MMTV integration site family, member 8B)

Identity

Other names-
HGNC (Hugo) WNT8B
LocusID (NCBI) 7479
Location 10q24.31
Location_base_pair Starts at 102222812 and ends at 102243399 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)WNT8B   12789
Cards
Entrez_Gene (NCBI)WNT8B  7479  wingless-type MMTV integration site family, member 8B
GeneCards (Weizmann)WNT8B
Ensembl hg19 (Hinxton)ENSG00000075290 [Gene_View]  chr10:102222812-102243399 [Contig_View]  WNT8B [Vega]
Ensembl hg38 (Hinxton)ENSG00000075290 [Gene_View]  chr10:102222812-102243399 [Contig_View]  WNT8B [Vega]
ICGC DataPortalENSG00000075290
cBioPortalWNT8B
AceView (NCBI)WNT8B
Genatlas (Paris)WNT8B
WikiGenes7479
SOURCE (Princeton)WNT8B
Genomic and cartography
GoldenPath hg19 (UCSC)WNT8B  -     chr10:102222812-102243399 +  10q24.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)WNT8B  -     10q24.31   [Description]    (hg38-Dec_2013)
EnsemblWNT8B - 10q24.31 [CytoView hg19]  WNT8B - 10q24.31 [CytoView hg38]
Mapping of homologs : NCBIWNT8B [Mapview hg19]  WNT8B [Mapview hg38]
OMIM601396   
Gene and transcription
Genbank (Entrez)AB073637 BC156632 CN276452 X91940 Y11094
RefSeq transcript (Entrez)NM_003393
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NT_030059 NW_001838006 NW_004929376
Consensus coding sequences : CCDS (NCBI)WNT8B
Cluster EST : UnigeneHs.421281 [ NCBI ]
CGAP (NCI)Hs.421281
Alternative Splicing : Fast-db (Paris)GSHG0003619
Alternative Splicing GalleryENSG00000075290
Gene ExpressionWNT8B [ NCBI-GEO ]     WNT8B [ SEEK ]   WNT8B [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ93098 (Uniprot)
NextProtQ93098  [Medical]
With graphics : InterProQ93098
Splice isoforms : SwissVarQ93098 (Swissvar)
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Wnt    Wnt8    Wnt_CS   
Related proteins : CluSTrQ93098
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
DMDM Disease mutations7479
Blocks (Seattle)Q93098
Human Protein AtlasENSG00000075290
Peptide AtlasQ93098
HPRD03235
IPIIPI00004125   
Protein Interaction databases
DIP (DOE-UCLA)Q93098
IntAct (EBI)Q93098
FunCoupENSG00000075290
BioGRIDWNT8B
IntegromeDBWNT8B
STRING (EMBL)WNT8B
Ontologies - Pathways
QuickGOQ93098
Ontology : AmiGOfrizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  signal transduction  gastrulation  nervous system development  positive regulation of gene expression  negative regulation of gene expression  Wnt signaling pathway  neuron differentiation  neuron differentiation  response to estradiol  response to retinoic acid  cell fate commitment  determination of dorsal identity  cellular response to retinoic acid  
Ontology : EGO-EBIfrizzled binding  extracellular region  proteinaceous extracellular matrix  extracellular space  signal transduction  gastrulation  nervous system development  positive regulation of gene expression  negative regulation of gene expression  Wnt signaling pathway  neuron differentiation  neuron differentiation  response to estradiol  response to retinoic acid  cell fate commitment  determination of dorsal identity  cellular response to retinoic acid  
Pathways : BIOCARTAWnt/LRP6 Signalling [Genes]   
Pathways : KEGGWnt signaling pathway    Hedgehog signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
Protein Interaction DatabaseWNT8B
DoCM (Curated mutations)WNT8B
Wikipedia pathwaysWNT8B
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerWNT8B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WNT8B
dbVarWNT8B
ClinVarWNT8B
1000_GenomesWNT8B 
Exome Variant ServerWNT8B
SNP (GeneSNP Utah)WNT8B
SNP : HGBaseWNT8B
Genetic variants : HAPMAPWNT8B
Genomic VariantsWNT8B  WNT8B [DGVbeta]
Mutations
ICGC Data PortalENSG00000075290 
Somatic Mutations in Cancer : COSMICWNT8B 
CONAN: Copy Number AnalysisWNT8B 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)10:102222812-102243399
Mutations and Diseases : HGMDWNT8B
OMIM601396   
MedgenWNT8B
NextProtQ93098 [Medical]
GENETestsWNT8B
Disease Genetic AssociationWNT8B
Huge Navigator WNT8B [HugePedia]  WNT8B [HugeCancerGEM]
snp3D : Map Gene to Disease7479
DGIdb (Drug Gene Interaction db)WNT8B
General knowledge
Homologs : HomoloGeneWNT8B
Homology/Alignments : Family Browser (UCSC)WNT8B
Phylogenetic Trees/Animal Genes : TreeFamWNT8B
Chemical/Protein Interactions : CTD7479
Chemical/Pharm GKB GenePA37390
Clinical trialWNT8B
Cancer Resource (Charite)ENSG00000075290
Other databases
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
CoreMineWNT8B
GoPubMedWNT8B
iHOPWNT8B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 02:18:50 CET 2014

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