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WNT8B (wingless-type MMTV integration site family, member 8B)

Identity

Other names-
HGNC (Hugo) WNT8B
LocusID (NCBI) 7479
Location 10q24.31
Location_base_pair Starts at 102222812 and ends at 102243399 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)WNT8B   12789
Entrez_Gene (NCBI)WNT8B  7479  wingless-type MMTV integration site family, member 8B
Cards
GeneCards (Weizmann)WNT8B
Ensembl (Hinxton)ENSG00000075290 [Gene_View]  chr10:102222812-102243399 [Contig_View]  WNT8B [Vega]
AceView (NCBI)WNT8B
Genatlas (Paris)WNT8B
SOURCE (Stanford)NM_003393
Genomic and cartography
GoldenPath (UCSC)WNT8B  -  10q24.31   chr10:102222812-102243399 +  10q24.31   [Description]    (hg19-Feb_2009)
EnsemblWNT8B - 10q24.31 [CytoView]
Mapping of homologs : NCBIWNT8B [Mapview]
OMIM601396   
Gene and transcription
Genbank (Entrez)AB073637 BC156632 CN276452 X91940 Y11094
RefSeq transcript (SRS)NM_003393
RefSeq transcript (Entrez)NM_003393
RefSeq genomic (SRS)AC_000142 NC_000010 NC_018921 NT_030059 NW_001838006 NW_004078068
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NT_030059 NW_001838006 NW_004078068
Consensus coding sequences : CCDS (NCBI)WNT8B
Cluster EST : UnigeneHs.421281 [ SRS ] Hs.421281 [ NCBI ]
CGAP (NCI)Hs.421281
Alternative Splicing : Fast-db (Paris)GSHG0003619
Alternative Splicing GalleryENSG00000075290
Gene ExpressionWNT8B [ NCBI-GEO ]   WNT8B [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ93098 (SRS) Q93098 (Uniprot)
NextProtQ93098
With graphics : InterProQ93098
Splice isoforms : SwissVarQ93098(Swissvar)
Domaine pattern : Prosite (SRS)WNT1 (PS00246)   
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (SRS)Wnt    Wnt8    Wnt_CS   
Domains : Interpro (EBI)Wnt    Wnt8    Wnt_CS   
Related proteins : CluSTrQ93098
Domain families : Pfam (SRS)wnt (PF00110)   
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
DMDM7479
Blocks (Seattle)Q93098
Human Protein AtlasENSG00000075290
HPRD03235
IPIIPI00004125   
Protein Interaction databases
DIP (DOE-UCLA)Q93098
IntAct (EBI)Q93098
FunCoupENSG00000075290
REACTOMEWNT8B
Protein Interaction Database7479
BioGRIDWNT8B
InParanoidQ93098
Interologous Interaction database Q93098
IntegromeDBWNT8B
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)WNT8B
SNP (GeneSNP Utah)WNT8B
SNP : HGBaseWNT8B
Genetic variants : HAPMAPWNT8B
Somatic Mutations in Cancer : COSMICWNT8B 
CONAN: Copy Number AnalysisWNT8B 
Mutations and Diseases : HGMDWNT8B
OMIM601396   
GENETests601396   
Disease Genetic AssociationWNT8B
Huge Navigator WNT8B [HugePedia]  WNT8B [HugeCancerGEM]
Genomic VariantsWNT8B  WNT8B [DGVbeta]
snp3D : Map Gene to Disease7479
General knowledge
Homologs : HomoloGeneWNT8B
Homology/Alignments : Family Browser (UCSC)WNT8B
Phylogenetic Trees/Animal Genes : TreeFamWNT8B
Chemical/Protein Interactions : CTD7479
Chemical/Pharm GKB GenePA37390
Clinical trialWNT8B
Cancer Resource (Charite)ENSG00000075290
Ontology : AmiGOeye development  G-protein coupled receptor binding  proteinaceous extracellular matrix  extracellular space  plasma membrane  signal transduction  gastrulation  nervous system development  endoderm development  axis specification  anterior/posterior pattern specification  positive regulation of gene expression  negative regulation of gene expression  hypothalamus development  Wnt receptor signaling pathway involved in forebrain neuron fate commitment  negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway  neuron differentiation  response to estradiol stimulus  response to retinoic acid  otic placode formation  determination of dorsal identity  canonical Wnt receptor signaling pathway  cellular response to retinoic acid  
Ontology : EGO-EBIeye development  G-protein coupled receptor binding  proteinaceous extracellular matrix  extracellular space  plasma membrane  signal transduction  gastrulation  nervous system development  endoderm development  axis specification  anterior/posterior pattern specification  positive regulation of gene expression  negative regulation of gene expression  hypothalamus development  Wnt receptor signaling pathway involved in forebrain neuron fate commitment  negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway  neuron differentiation  response to estradiol stimulus  response to retinoic acid  otic placode formation  determination of dorsal identity  canonical Wnt receptor signaling pathway  cellular response to retinoic acid  
Pathways : BIOCARTAWnt/LRP6 Signalling [Genes]   
Pathways : KEGGHedgehog signaling pathwayWnt signaling pathway
Other databases
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
PubGeneWNT8B
iHOPWNT8B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:41:13 CEST 2013
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