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WNT8B (Wnt family member 8B)

Identity

Alias (NCBI)-
HGNC (Hugo) WNT8B
HGNC Previous namewingless-type MMTV integration site family, member 8B
LocusID (NCBI) 7479
Atlas_Id 42831
Location 10q24.31  [Link to chromosome band 10q24]
Location_base_pair Starts at 100463009 and ends at 100483744 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)WNT8B   12789
Cards
Entrez_Gene (NCBI)WNT8B    Wnt family member 8B
Aliases
GeneCards (Weizmann)WNT8B
Ensembl hg19 (Hinxton)ENSG00000075290 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000075290 [Gene_View]  ENSG00000075290 [Sequence]  chr10:100463009-100483744 [Contig_View]  WNT8B [Vega]
ICGC DataPortalENSG00000075290
TCGA cBioPortalWNT8B
AceView (NCBI)WNT8B
Genatlas (Paris)WNT8B
SOURCE (Princeton)WNT8B
Genetics Home Reference (NIH)WNT8B
Genomic and cartography
GoldenPath hg38 (UCSC)WNT8B  -     chr10:100463009-100483744 +  10q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WNT8B  -     10q24.31   [Description]    (hg19-Feb_2009)
GoldenPathWNT8B - 10q24.31 [CytoView hg19]  WNT8B - 10q24.31 [CytoView hg38]
ImmunoBaseENSG00000075290
genome Data Viewer NCBIWNT8B [Mapview hg19]  
OMIM601396   
Gene and transcription
Genbank (Entrez)AB073637 CN276452 GQ891471 X91940 Y11094
RefSeq transcript (Entrez)NM_003393
Consensus coding sequences : CCDS (NCBI)WNT8B
Alternative Splicing GalleryENSG00000075290
Gene ExpressionWNT8B [ NCBI-GEO ]   WNT8B [ EBI - ARRAY_EXPRESS ]   WNT8B [ SEEK ]   WNT8B [ MEM ]
Gene Expression Viewer (FireBrowse)WNT8B [ Firebrowse - Broad ]
GenevisibleExpression of WNT8B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7479
GTEX Portal (Tissue expression)WNT8B
Human Protein AtlasENSG00000075290-WNT8B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ93098   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ93098  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ93098
PhosPhoSitePlusQ93098
Domaine pattern : Prosite (Expaxy)WNT1 (PS00246)   
Domains : Interpro (EBI)Protein_Wnt-8B    Wnt    Wnt8    Wnt_C    Wnt_CS   
Domain families : Pfam (Sanger)wnt (PF00110)   
Domain families : Pfam (NCBI)pfam00110   
Domain families : Smart (EMBL)WNT1 (SM00097)  
Conserved Domain (NCBI)WNT8B
SuperfamilyQ93098
AlphaFold pdb e-kbQ93098   
Human Protein Atlas [tissue]ENSG00000075290-WNT8B [tissue]
HPRD03235
Protein Interaction databases
DIP (DOE-UCLA)Q93098
IntAct (EBI)Q93098
BioGRIDWNT8B
STRING (EMBL)WNT8B
ZODIACWNT8B
Ontologies - Pathways
QuickGOQ93098
Ontology : AmiGOfrizzled binding  cytokine activity  extracellular region  extracellular space  signal transduction  gastrulation  nervous system development  Wnt signaling pathway  neuron differentiation  neuron differentiation  response to estradiol  response to retinoic acid  cell fate commitment  receptor ligand activity  determination of dorsal identity  canonical Wnt signaling pathway  canonical Wnt signaling pathway  cellular response to retinoic acid  beta-catenin destruction complex disassembly  
Ontology : EGO-EBIfrizzled binding  cytokine activity  extracellular region  extracellular space  signal transduction  gastrulation  nervous system development  Wnt signaling pathway  neuron differentiation  neuron differentiation  response to estradiol  response to retinoic acid  cell fate commitment  receptor ligand activity  determination of dorsal identity  canonical Wnt signaling pathway  canonical Wnt signaling pathway  cellular response to retinoic acid  beta-catenin destruction complex disassembly  
Pathways : BIOCARTAWnt/LRP6 Signalling [Genes]   
Pathways : KEGGWnt signaling pathway    Hedgehog signaling pathway    Hippo signaling pathway    Melanogenesis    HTLV-I infection    Pathways in cancer    Proteoglycans in cancer    Basal cell carcinoma   
NDEx NetworkWNT8B
Atlas of Cancer Signalling NetworkWNT8B
Wikipedia pathwaysWNT8B
Orthology - Evolution
OrthoDB7479
GeneTree (enSembl)ENSG00000075290
Phylogenetic Trees/Animal Genes : TreeFamWNT8B
Homologs : HomoloGeneWNT8B
Homology/Alignments : Family Browser (UCSC)WNT8B
Gene fusions - Rearrangements
Fusion : QuiverWNT8B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWNT8B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WNT8B
dbVarWNT8B
ClinVarWNT8B
MonarchWNT8B
1000_GenomesWNT8B 
Exome Variant ServerWNT8B
GNOMAD BrowserENSG00000075290
Varsome BrowserWNT8B
Genomic Variants (DGV)WNT8B [DGVbeta]
DECIPHERWNT8B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWNT8B 
Mutations
ICGC Data PortalWNT8B 
TCGA Data PortalWNT8B 
Broad Tumor PortalWNT8B
OASIS PortalWNT8B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWNT8B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DWNT8B
Mutations and Diseases : HGMDWNT8B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutasearch WNT8B
DgiDB (Drug Gene Interaction Database)WNT8B
DoCM (Curated mutations)WNT8B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WNT8B (select a term)
Cancer3DWNT8B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601396   
Orphanet
DisGeNETWNT8B
MedgenWNT8B
Genetic Testing Registry WNT8B
NextProtQ93098 [Medical]
GENETestsWNT8B
Target ValidationWNT8B
Huge Navigator WNT8B [HugePedia]
ClinGenWNT8B
Clinical trials, drugs, therapy
MyCancerGenomeWNT8B
Protein Interactions : CTDWNT8B
Pharm GKB GenePA37390
PharosQ93098
Clinical trialWNT8B
Miscellaneous
canSAR (ICR)WNT8B
HarmonizomeWNT8B
DataMed IndexWNT8B
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXWNT8B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Sep 15 22:44:06 CEST 2021

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