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WRAP73 (WD repeat containing, antisense to TP73)

Identity

Alias_namesWDR8
WD repeat domain 8
Other alias
HGNC (Hugo) WRAP73
LocusID (NCBI) 49856
Atlas_Id 75767
Location 1p36.32  [Link to chromosome band 1p36]
Location_base_pair Starts at 3630767 and ends at 3650107 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MEGF6 (1p36.32) / WRAP73 (1p36.32)WRAP73 (1p36.32) / RGPD1 (2p11.2)WRAP73 (1p36.32) / TOB2P1 (6p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WRAP73   12759
Cards
Entrez_Gene (NCBI)WRAP73  49856  WD repeat containing, antisense to TP73
AliasesWDR8
GeneCards (Weizmann)WRAP73
Ensembl hg19 (Hinxton)ENSG00000116213 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116213 [Gene_View]  chr1:3630767-3650107 [Contig_View]  WRAP73 [Vega]
ICGC DataPortalENSG00000116213
TCGA cBioPortalWRAP73
AceView (NCBI)WRAP73
Genatlas (Paris)WRAP73
WikiGenes49856
SOURCE (Princeton)WRAP73
Genetics Home Reference (NIH)WRAP73
Genomic and cartography
GoldenPath hg38 (UCSC)WRAP73  -     chr1:3630767-3650107 -  1p36.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WRAP73  -     1p36.32   [Description]    (hg19-Feb_2009)
EnsemblWRAP73 - 1p36.32 [CytoView hg19]  WRAP73 - 1p36.32 [CytoView hg38]
Mapping of homologs : NCBIWRAP73 [Mapview hg19]  WRAP73 [Mapview hg38]
OMIM606040   
Gene and transcription
Genbank (Entrez)AB034912 AI376011 AK000437 AK225525 AK302397
RefSeq transcript (Entrez)NM_017818
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WRAP73
Cluster EST : UnigeneHs.31714 [ NCBI ]
CGAP (NCI)Hs.31714
Alternative Splicing GalleryENSG00000116213
Gene ExpressionWRAP73 [ NCBI-GEO ]   WRAP73 [ EBI - ARRAY_EXPRESS ]   WRAP73 [ SEEK ]   WRAP73 [ MEM ]
Gene Expression Viewer (FireBrowse)WRAP73 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)49856
GTEX Portal (Tissue expression)WRAP73
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2S5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2S5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2S5
Splice isoforms : SwissVarQ9P2S5
PhosPhoSitePlusQ9P2S5
Domains : Interpro (EBI)Apc4_WD40_dom    WD40/YVTN_repeat-like_dom    WD40_repeat   
Domain families : Pfam (Sanger)ANAPC4_WD40 (PF12894)   
Domain families : Pfam (NCBI)pfam12894   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)WRAP73
DMDM Disease mutations49856
Blocks (Seattle)WRAP73
SuperfamilyQ9P2S5
Human Protein AtlasENSG00000116213
Peptide AtlasQ9P2S5
HPRD06918
IPIIPI00293015   IPI00644542   IPI00514559   IPI00514069   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2S5
IntAct (EBI)Q9P2S5
FunCoupENSG00000116213
BioGRIDWRAP73
STRING (EMBL)WRAP73
ZODIACWRAP73
Ontologies - Pathways
QuickGOQ9P2S5
Ontology : AmiGOprotein binding  centrosome  centriole  cell projection organization  ciliary basal body  mitotic spindle assembly  positive regulation of non-motile cilium assembly  
Ontology : EGO-EBIprotein binding  centrosome  centriole  cell projection organization  ciliary basal body  mitotic spindle assembly  positive regulation of non-motile cilium assembly  
NDEx NetworkWRAP73
Atlas of Cancer Signalling NetworkWRAP73
Wikipedia pathwaysWRAP73
Orthology - Evolution
OrthoDB49856
GeneTree (enSembl)ENSG00000116213
Phylogenetic Trees/Animal Genes : TreeFamWRAP73
HOVERGENQ9P2S5
HOGENOMQ9P2S5
Homologs : HomoloGeneWRAP73
Homology/Alignments : Family Browser (UCSC)WRAP73
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWRAP73 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WRAP73
dbVarWRAP73
ClinVarWRAP73
1000_GenomesWRAP73 
Exome Variant ServerWRAP73
ExAC (Exome Aggregation Consortium)WRAP73 (select the gene name)
Genetic variants : HAPMAP49856
Genomic Variants (DGV)WRAP73 [DGVbeta]
DECIPHERWRAP73 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWRAP73 
Mutations
ICGC Data PortalWRAP73 
TCGA Data PortalWRAP73 
Broad Tumor PortalWRAP73
OASIS PortalWRAP73 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWRAP73  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWRAP73
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WRAP73
DgiDB (Drug Gene Interaction Database)WRAP73
DoCM (Curated mutations)WRAP73 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WRAP73 (select a term)
intoGenWRAP73
Cancer3DWRAP73(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606040   
Orphanet
MedgenWRAP73
Genetic Testing Registry WRAP73
NextProtQ9P2S5 [Medical]
TSGene49856
GENETestsWRAP73
Target ValidationWRAP73
Huge Navigator WRAP73 [HugePedia]
snp3D : Map Gene to Disease49856
BioCentury BCIQWRAP73
ClinGenWRAP73
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD49856
Chemical/Pharm GKB GenePA37363
Clinical trialWRAP73
Miscellaneous
canSAR (ICR)WRAP73 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWRAP73
EVEXWRAP73
GoPubMedWRAP73
iHOPWRAP73
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:49:07 CEST 2017

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