Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WSB2 (WD repeat and SOCS box containing 2)

Identity

Alias_namesWD repeat and SOCS box-containing 2
Alias_symbol (synonym)SBA2
MGC10210
Other alias
HGNC (Hugo) WSB2
LocusID (NCBI) 55884
Atlas_Id 46462
Location 12q24.23  [Link to chromosome band 12q24]
Location_base_pair Starts at 118032691 and ends at 118062174 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CCDC18 (1p22.1) / WSB2 (12q24.23)WSB2 (12q24.23) / RFC5 (12q24.23)WSB2 (12q24.23) / VSIG10 (12q24.23)
WSB2 (12q24.23) / WSB2 (12q24.23)WSB2 12q24.23 / RFC5 12q24.23WSB2 12q24.23 / VSIG10 12q24.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WSB2   19222
Cards
Entrez_Gene (NCBI)WSB2  55884  WD repeat and SOCS box containing 2
AliasesSBA2
GeneCards (Weizmann)WSB2
Ensembl hg19 (Hinxton)ENSG00000176871 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176871 [Gene_View]  chr12:118032691-118062174 [Contig_View]  WSB2 [Vega]
ICGC DataPortalENSG00000176871
TCGA cBioPortalWSB2
AceView (NCBI)WSB2
Genatlas (Paris)WSB2
WikiGenes55884
SOURCE (Princeton)WSB2
Genetics Home Reference (NIH)WSB2
Genomic and cartography
GoldenPath hg38 (UCSC)WSB2  -     chr12:118032691-118062174 -  12q24.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WSB2  -     12q24.23   [Description]    (hg19-Feb_2009)
EnsemblWSB2 - 12q24.23 [CytoView hg19]  WSB2 - 12q24.23 [CytoView hg38]
Mapping of homologs : NCBIWSB2 [Mapview hg19]  WSB2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF038187 AF163324 AF229181 AK294230 AK295555
RefSeq transcript (Entrez)NM_001278557 NM_001278558 NM_018639
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WSB2
Cluster EST : UnigeneHs.506985 [ NCBI ]
CGAP (NCI)Hs.506985
Alternative Splicing GalleryENSG00000176871
Gene ExpressionWSB2 [ NCBI-GEO ]   WSB2 [ EBI - ARRAY_EXPRESS ]   WSB2 [ SEEK ]   WSB2 [ MEM ]
Gene Expression Viewer (FireBrowse)WSB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55884
GTEX Portal (Tissue expression)WSB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYS7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYS7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYS7
Splice isoforms : SwissVarQ9NYS7
PhosPhoSitePlusQ9NYS7
Domaine pattern : Prosite (Expaxy)SOCS (PS50225)    WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    SOCS_box    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)SOCS_box (PF07525)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam07525    pfam00400   
Domain families : Smart (EMBL)SOCS (SM00253)  SOCS_box (SM00969)  WD40 (SM00320)  
Conserved Domain (NCBI)WSB2
DMDM Disease mutations55884
Blocks (Seattle)WSB2
SuperfamilyQ9NYS7
Human Protein AtlasENSG00000176871
Peptide AtlasQ9NYS7
HPRD18305
IPIIPI00941604   IPI01010292   IPI01014617   IPI00032828   IPI01011081   IPI01012409   IPI01011497   IPI01011013   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYS7
IntAct (EBI)Q9NYS7
FunCoupENSG00000176871
BioGRIDWSB2
STRING (EMBL)WSB2
ZODIACWSB2
Ontologies - Pathways
QuickGOQ9NYS7
Ontology : AmiGOintracellular  protein ubiquitination  intracellular signal transduction  
Ontology : EGO-EBIintracellular  protein ubiquitination &~bsp;4a`href= http://www.ebi.ac.uk/ego/DisplayGoTerm?id=GO:0035556 TARGET=EGO>intracellular signal transduction  
NDEx NetworkWSB2
Atlas of Cancer Signalling NetworkWSB2
Wikipedia pathwaysWSB2
Orthology - Evolution
OrthoDB55884
GeneTree (enSembl)ENSG00000176871
Phylogenetic Trees/Animal Genes : TreeFamWSB2
HOVERGENQ9NYS7
HOGENOMQ9NYS7
Homologs : HomoloGeneWSB2
Homology/Alignments : Family Browser (UCSC)WSB2
Gene fusions - Rearrangements
Fusion : MitelmanWSB2/RFC5 [12q24.23/12q24.23]  
Fusion : MitelmanWSB2/VSIG10 [12q24.23/12q24.23]  [t(12;12)(q24;q24)]  
Fusion: TCGAWSB2 12q24.23 RFC5 12q24.23 LUAD
Fusion: TCGAWSB2 12q24.23 VSIG10 12q24.23 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWSB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WSB2
dbVarWSB2
ClinVarWSB2
1000_GenomesWSB2 
Exome Variant ServerWSB2
ExAC (Exome Aggregation Consortium)WSB2 (select the gene name)
Genetic variants : HAPMAP55884
Genomic Variants (DGV)WSB2 [DGVbeta]
DECIPHERWSB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWSB2 
Mutations
ICGC Data PortalWSB2 
TCGA Data PortalWSB2 
Broad Tumor PortalWSB2
OASIS PortalWSB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWSB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWSB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WSB2
DgiDB (Drug Gene Interaction Database)WSB2
DoCM (Curated mutations)WSB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WSB2 (select a term)
intoGenWSB2
Cancer3DWSB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenWSB2
Genetic Testing Registry WSB2
NextProtQ9NYS7 [Medical]
TSGene55884
GENETestsWSB2
Target ValidationWSB2
Huge Navigator WSB2 [HugePedia]
snp3D : Map Gene to Disease55884
BioCentury BCIQWSB2
ClinGenWSB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55884
Chemical/Pharm GKB GenePA128395787
Clinical trialWSB2
Miscellaneous
canSAR (ICR)WSB2 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWSB2
EVEXWSB2
GoPubMedWSB2
iHOPWSB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:38:26 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.