Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

WTAP (WT1 associated protein)

Identity

Alias_symbol (synonym)KIAA0105
MGC3925
Mum2
Other alias
HGNC (Hugo) WTAP
LocusID (NCBI) 9589
Atlas_Id 42838
Location 6q25.3  [Link to chromosome band 6q25]
Location_base_pair Starts at 159727500 and ends at 159756321 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BPTF (17q24.2) / WTAP (6q25.3)FLNA (Xq28) / WTAP (6q25.3)IGF2R (6q25.3) / WTAP (6q25.3)
WTAP (6q25.3) / CBR4 (4q32.3)WTAP (6q25.3) / SOCS2 (12q22)IGF2R 6q25.3 / WTAP 6q25.3
WTAP 6q25.3 / SOCS2 12q22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)WTAP   16846
Cards
Entrez_Gene (NCBI)WTAP  9589  WT1 associated protein
AliasesMum2
GeneCards (Weizmann)WTAP
Ensembl hg19 (Hinxton)ENSG00000146457 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146457 [Gene_View]  chr6:159727500-159756321 [Contig_View]  WTAP [Vega]
ICGC DataPortalENSG00000146457
TCGA cBioPortalWTAP
AceView (NCBI)WTAP
Genatlas (Paris)WTAP
WikiGenes9589
SOURCE (Princeton)WTAP
Genetics Home Reference (NIH)WTAP
Genomic and cartography
GoldenPath hg38 (UCSC)WTAP  -     chr6:159727500-159756321 +  6q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WTAP  -     6q25.3   [Description]    (hg19-Feb_2009)
EnsemblWTAP - 6q25.3 [CytoView hg19]  WTAP - 6q25.3 [CytoView hg38]
Mapping of homologs : NCBIWTAP [Mapview hg19]  WTAP [Mapview hg38]
OMIM605442   
Gene and transcription
Genbank (Entrez)AA706250 AF277190 AF374416 AJ276706 AK127822
RefSeq transcript (Entrez)NM_001270531 NM_001270532 NM_001270533 NM_004906 NM_152857 NM_152858
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WTAP
Cluster EST : UnigeneHs.446091 [ NCBI ]
CGAP (NCI)Hs.446091
Alternative Splicing GalleryENSG00000146457
Gene ExpressionWTAP [ NCBI-GEO ]   WTAP [ EBI - ARRAY_EXPRESS ]   WTAP [ SEEK ]   WTAP [ MEM ]
Gene Expression Viewer (FireBrowse)WTAP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9589
GTEX Portal (Tissue expression)WTAP
Human Protein AtlasENSG00000146457-WTAP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15007   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15007  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15007
Splice isoforms : SwissVarQ15007
PhosPhoSitePlusQ15007
Domains : Interpro (EBI)WTAP    WTAP/Mum2   
Domain families : Pfam (Sanger)Wtap (PF17098)   
Domain families : Pfam (NCBI)pfam17098   
Conserved Domain (NCBI)WTAP
DMDM Disease mutations9589
Blocks (Seattle)WTAP
SuperfamilyQ15007
Human Protein Atlas [tissue]ENSG00000146457-WTAP [tissue]
Peptide AtlasQ15007
HPRD09259
IPIIPI00220302   IPI00014150   
Protein Interaction databases
DIP (DOE-UCLA)Q15007
IntAct (EBI)Q15007
FunCoupENSG00000146457
BioGRIDWTAP
STRING (EMBL)WTAP
ZODIACWTAP
Ontologies - Pathways
QuickGOQ15007
Ontology : AmiGOregulation of alternative mRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  nucleoplasm  mRNA processing  cell cycle  RNA splicing  gene expression  nuclear speck  nuclear membrane  MIS complex  mRNA methylation  
Ontology : EGO-EBIregulation of alternative mRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  nucleoplasm  mRNA processing  cell cycle  RNA splicing  gene expression  nuclear speck  nuclear membrane  MIS complex  mRNA methylation  
NDEx NetworkWTAP
Atlas of Cancer Signalling NetworkWTAP
Wikipedia pathwaysWTAP
Orthology - Evolution
OrthoDB9589
GeneTree (enSembl)ENSG00000146457
Phylogenetic Trees/Animal Genes : TreeFamWTAP
HOVERGENQ15007
HOGENOMQ15007
Homologs : HomoloGeneWTAP
Homology/Alignments : Family Browser (UCSC)WTAP
Gene fusions - Rearrangements
Fusion : MitelmanIGF2R/WTAP [6q25.3/6q25.3]  [t(6;6)(q25;q25)]  
Fusion : MitelmanWTAP/SOCS2 [6q25.3/12q22]  [t(6;12)(q25;q22)]  
Fusion: TCGA_MDACCIGF2R 6q25.3 WTAP 6q25.3 LUAD
Fusion: TCGA_MDACCWTAP 6q25.3 SOCS2 12q22 PRAD
Tumor Fusion PortalWTAP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWTAP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WTAP
dbVarWTAP
ClinVarWTAP
1000_GenomesWTAP 
Exome Variant ServerWTAP
ExAC (Exome Aggregation Consortium)ENSG00000146457
GNOMAD BrowserENSG00000146457
Genetic variants : HAPMAP9589
Genomic Variants (DGV)WTAP [DGVbeta]
DECIPHERWTAP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWTAP 
Mutations
ICGC Data PortalWTAP 
TCGA Data PortalWTAP 
Broad Tumor PortalWTAP
OASIS PortalWTAP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWTAP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWTAP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WTAP
DgiDB (Drug Gene Interaction Database)WTAP
DoCM (Curated mutations)WTAP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WTAP (select a term)
intoGenWTAP
Cancer3DWTAP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605442   
Orphanet
DisGeNETWTAP
MedgenWTAP
Genetic Testing Registry WTAP
NextProtQ15007 [Medical]
TSGene9589
GENETestsWTAP
Target ValidationWTAP
Huge Navigator WTAP [HugePedia]
snp3D : Map Gene to Disease9589
BioCentury BCIQWTAP
ClinGenWTAP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9589
Chemical/Pharm GKB GenePA134864847
Clinical trialWTAP
Miscellaneous
canSAR (ICR)WTAP (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWTAP
EVEXWTAP
GoPubMedWTAP
iHOPWTAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:41:48 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.