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WTIP (WT1 interacting protein)

Identity

Other alias-
HGNC (Hugo) WTIP
LocusID (NCBI) 126374
Atlas_Id 43046
Location 19q13.11  [Link to chromosome band 19q13]
Location_base_pair Starts at 34481975 and ends at 34501180 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FJX1 (11p13) / WTIP (19q13.11)UBA2 (19q13.11) / WTIP (19q13.11)WTIP (19q13.11) / GPI (19q13.11)
WTIP (19q13.11) / KIAA0355 (19q13.11)WTIP 19q13.11 / KIAA0355 19q13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 8 ]
  t(2;19)(p22;q13) WTIP/BIRC6
UBA2/WTIP (19q13)
UBA2/WTIP (19q13)
UBA2/WTIP (19q13)
UBA2/WTIP (19q13)
UBA2/WTIP (19q13)
WTIP/KIAA0355 (19q13)
t(19;20)(q13;p12) PLCB1/WTIP


External links

Nomenclature
HGNC (Hugo)WTIP   20964
Cards
Entrez_Gene (NCBI)WTIP  126374  WT1 interacting protein
Aliases
GeneCards (Weizmann)WTIP
Ensembl hg19 (Hinxton)ENSG00000142279 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142279 [Gene_View]  ENSG00000142279 [Sequence]  chr19:34481975-34501180 [Contig_View]  WTIP [Vega]
ICGC DataPortalENSG00000142279
TCGA cBioPortalWTIP
AceView (NCBI)WTIP
Genatlas (Paris)WTIP
WikiGenes126374
SOURCE (Princeton)WTIP
Genetics Home Reference (NIH)WTIP
Genomic and cartography
GoldenPath hg38 (UCSC)WTIP  -     chr19:34481975-34501180 +  19q13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)WTIP  -     19q13.11   [Description]    (hg19-Feb_2009)
EnsemblWTIP - 19q13.11 [CytoView hg19]  WTIP - 19q13.11 [CytoView hg38]
Mapping of homologs : NCBIWTIP [Mapview hg19]  WTIP [Mapview hg38]
OMIM614790   
Gene and transcription
Genbank (Entrez)AK130059 BC030216
RefSeq transcript (Entrez)NM_001080436
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)WTIP
Cluster EST : UnigeneHs.585010 [ NCBI ]
CGAP (NCI)Hs.585010
Alternative Splicing GalleryENSG00000142279
Gene ExpressionWTIP [ NCBI-GEO ]   WTIP [ EBI - ARRAY_EXPRESS ]   WTIP [ SEEK ]   WTIP [ MEM ]
Gene Expression Viewer (FireBrowse)WTIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)126374
GTEX Portal (Tissue expression)WTIP
Human Protein AtlasENSG00000142279-WTIP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA6NIX2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA6NIX2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA6NIX2
Splice isoforms : SwissVarA6NIX2
PhosPhoSitePlusA6NIX2
Domaine pattern : Prosite (Expaxy)LIM_DOMAIN_1 (PS00478)    LIM_DOMAIN_2 (PS50023)   
Domains : Interpro (EBI)Znf_LIM   
Domain families : Pfam (Sanger)LIM (PF00412)   
Domain families : Pfam (NCBI)pfam00412   
Domain families : Smart (EMBL)LIM (SM00132)  
Conserved Domain (NCBI)WTIP
DMDM Disease mutations126374
Blocks (Seattle)WTIP
SuperfamilyA6NIX2
Human Protein Atlas [tissue]ENSG00000142279-WTIP [tissue]
Peptide AtlasA6NIX2
IPIIPI00787845   
Protein Interaction databases
DIP (DOE-UCLA)A6NIX2
IntAct (EBI)A6NIX2
FunCoupENSG00000142279
BioGRIDWTIP
STRING (EMBL)WTIP
ZODIACWTIP
Ontologies - Pathways
QuickGOA6NIX2
Ontology : AmiGOP-body  P-body  response to hypoxia  response to hypoxia  transcription corepressor activity  protein binding  nucleus  transcription factor complex  cell-cell junction  adherens junction  transcription, DNA-templated  regulation of transcription, DNA-templated  cytoskeleton organization  cytoskeleton organization  regulation of cell morphogenesis  cell projection organization  gene silencing by miRNA  hippo signaling  negative regulation of hippo signaling  negative regulation of hippo signaling  metal ion binding  negative regulation of nucleic acid-templated transcription  positive regulation of gene silencing by miRNA  positive regulation of gene silencing by miRNA  
Ontology : EGO-EBIP-body  P-body  response to hypoxia  response to hypoxia  transcription corepressor activity  protein binding  nucleus  transcription factor complex  cell-cell junction  adherens junction  transcription, DNA-templated  regulation of transcription, DNA-templated  cytoskeleton organization  cytoskeleton organization  regulation of cell morphogenesis  cell projection organization  gene silencing by miRNA  hippo signaling  negative regulation of hippo signaling  negative regulation of hippo signaling  metal ion binding  negative regulation of nucleic acid-templated transcription  positive regulation of gene silencing by miRNA  positive regulation of gene silencing by miRNA  
Pathways : KEGGHippo signaling pathway   
NDEx NetworkWTIP
Atlas of Cancer Signalling NetworkWTIP
Wikipedia pathwaysWTIP
Orthology - Evolution
OrthoDB126374
GeneTree (enSembl)ENSG00000142279
Phylogenetic Trees/Animal Genes : TreeFamWTIP
HOVERGENA6NIX2
HOGENOMA6NIX2
Homologs : HomoloGeneWTIP
Homology/Alignments : Family Browser (UCSC)WTIP
Gene fusions - Rearrangements
Fusion : MitelmanWTIP/KIAA0355 [19q13.11/19q13.11]  
Fusion PortalWTIP 19q13.11 KIAA0355 19q13.11 BRCA
Fusion : QuiverWTIP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerWTIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)WTIP
dbVarWTIP
ClinVarWTIP
1000_GenomesWTIP 
Exome Variant ServerWTIP
ExAC (Exome Aggregation Consortium)ENSG00000142279
GNOMAD BrowserENSG00000142279
Varsome BrowserWTIP
Genetic variants : HAPMAP126374
Genomic Variants (DGV)WTIP [DGVbeta]
DECIPHERWTIP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisWTIP 
Mutations
ICGC Data PortalWTIP 
TCGA Data PortalWTIP 
Broad Tumor PortalWTIP
OASIS PortalWTIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICWTIP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDWTIP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch WTIP
DgiDB (Drug Gene Interaction Database)WTIP
DoCM (Curated mutations)WTIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)WTIP (select a term)
intoGenWTIP
Cancer3DWTIP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614790   
Orphanet
DisGeNETWTIP
MedgenWTIP
Genetic Testing Registry WTIP
NextProtA6NIX2 [Medical]
TSGene126374
GENETestsWTIP
Target ValidationWTIP
Huge Navigator WTIP [HugePedia]
snp3D : Map Gene to Disease126374
BioCentury BCIQWTIP
ClinGenWTIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD126374
Chemical/Pharm GKB GenePA142670568
Clinical trialWTIP
Miscellaneous
canSAR (ICR)WTIP (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineWTIP
EVEXWTIP
GoPubMedWTIP
iHOPWTIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 12:02:02 CEST 2018

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