Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

XCL2 (X-C motif chemokine ligand 2)

Identity

Alias_namesSCYC2
small inducible cytokine subfamily C, member 2
chemokine (C motif) ligand 2
Alias_symbol (synonym)SCM-1b
Other aliasSCM1B
HGNC (Hugo) XCL2
LocusID (NCBI) 6846
Atlas_Id 55230
Location 1q24.2  [Link to chromosome band 1q24]
Location_base_pair Starts at 168510003 and ends at 168513235 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)XCL2   10646
Cards
Entrez_Gene (NCBI)XCL2  6846  X-C motif chemokine ligand 2
AliasesSCM-1b; SCM1B; SCYC2
GeneCards (Weizmann)XCL2
Ensembl hg19 (Hinxton)ENSG00000143185 [Gene_View]  chr1:168510003-168513235 [Contig_View]  XCL2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143185 [Gene_View]  chr1:168510003-168513235 [Contig_View]  XCL2 [Vega]
ICGC DataPortalENSG00000143185
TCGA cBioPortalXCL2
AceView (NCBI)XCL2
Genatlas (Paris)XCL2
WikiGenes6846
SOURCE (Princeton)XCL2
Genetics Home Reference (NIH)XCL2
Genomic and cartography
GoldenPath hg19 (UCSC)XCL2  -     chr1:168510003-168513235 -  1q24.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)XCL2  -     1q24.2   [Description]    (hg38-Dec_2013)
EnsemblXCL2 - 1q24.2 [CytoView hg19]  XCL2 - 1q24.2 [CytoView hg38]
Mapping of homologs : NCBIXCL2 [Mapview hg19]  XCL2 [Mapview hg38]
OMIM604828   
Gene and transcription
Genbank (Entrez)BC069360 BC070308 BE218461 CD521967
RefSeq transcript (Entrez)NM_003175
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)XCL2
Cluster EST : UnigeneHs.458346 [ NCBI ]
CGAP (NCI)Hs.458346
Alternative Splicing GalleryENSG00000143185
Gene ExpressionXCL2 [ NCBI-GEO ]   XCL2 [ EBI - ARRAY_EXPRESS ]   XCL2 [ SEEK ]   XCL2 [ MEM ]
Gene Expression Viewer (FireBrowse)XCL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6846
GTEX Portal (Tissue expression)XCL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBD3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBD3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBD3
Splice isoforms : SwissVarQ9UBD3
PhosPhoSitePlusQ9UBD3
Domains : Interpro (EBI)Chemokine_IL8-like_dom    Chemokine_XCL1   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)XCL2
DMDM Disease mutations6846
Blocks (Seattle)XCL2
SuperfamilyQ9UBD3
Human Protein AtlasENSG00000143185
Peptide AtlasQ9UBD3
HPRD05317
IPIIPI00002528   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBD3
IntAct (EBI)Q9UBD3
FunCoupENSG00000143185
BioGRIDXCL2
STRING (EMBL)XCL2
ZODIACXCL2
Ontologies - Pathways
QuickGOQ9UBD3
Ontology : AmiGOmonocyte chemotaxis  protein binding  extracellular region  extracellular space  inflammatory response  signal transduction  G-protein coupled receptor signaling pathway  chemokine activity  blood circulation  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  positive regulation of inflammatory response  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImonocyte chemotaxis  protein binding  extracellular region  extracellular space  inflammatory response  signal transduction  G-protein coupled receptor signaling pathway  chemokine activity  blood circulation  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  positive regulation of inflammatory response  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkXCL2
Atlas of Cancer Signalling NetworkXCL2
Wikipedia pathwaysXCL2
Orthology - Evolution
OrthoDB6846
GeneTree (enSembl)ENSG00000143185
Phylogenetic Trees/Animal Genes : TreeFamXCL2
HOVERGENQ9UBD3
HOGENOMQ9UBD3
Homologs : HomoloGeneXCL2
Homology/Alignments : Family Browser (UCSC)XCL2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerXCL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)XCL2
dbVarXCL2
ClinVarXCL2
1000_GenomesXCL2 
Exome Variant ServerXCL2
ExAC (Exome Aggregation Consortium)XCL2 (select the gene name)
Genetic variants : HAPMAP6846
Genomic Variants (DGV)XCL2 [DGVbeta]
DECIPHER (Syndromes)1:168510003-168513235  ENSG00000143185
CONAN: Copy Number AnalysisXCL2 
Mutations
ICGC Data PortalXCL2 
TCGA Data PortalXCL2 
Broad Tumor PortalXCL2
OASIS PortalXCL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICXCL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDXCL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch XCL2
DgiDB (Drug Gene Interaction Database)XCL2
DoCM (Curated mutations)XCL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)XCL2 (select a term)
intoGenXCL2
Cancer3DXCL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604828   
Orphanet
MedgenXCL2
Genetic Testing Registry XCL2
NextProtQ9UBD3 [Medical]
TSGene6846
GENETestsXCL2
Huge Navigator XCL2 [HugePedia]
snp3D : Map Gene to Disease6846
BioCentury BCIQXCL2
ClinGenXCL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6846
Chemical/Pharm GKB GenePA35576
Clinical trialXCL2
Miscellaneous
canSAR (ICR)XCL2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineXCL2
EVEXXCL2
GoPubMedXCL2
iHOPXCL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:25:11 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.