Atlas of Genetics and Cytogenetics in Oncology and Haematology


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XCR1 (X-C motif chemokine receptor 1)

Identity

Alias_namesGPR5
CCXCR1
chemokine (C motif) XC receptor 1
chemokine (C motif) receptor 1
Other alias
HGNC (Hugo) XCR1
LocusID (NCBI) 2829
Atlas_Id 49758
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 46020799 and ends at 46027487 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TNKS1BP1 (11q12.1) / XCR1 (3p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)XCR1   1625
Cards
Entrez_Gene (NCBI)XCR1  2829  X-C motif chemokine receptor 1
AliasesCCXCR1; GPR5
GeneCards (Weizmann)XCR1
Ensembl hg19 (Hinxton)ENSG00000173578 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173578 [Gene_View]  chr3:46020799-46027487 [Contig_View]  XCR1 [Vega]
ICGC DataPortalENSG00000173578
TCGA cBioPortalXCR1
AceView (NCBI)XCR1
Genatlas (Paris)XCR1
WikiGenes2829
SOURCE (Princeton)XCR1
Genetics Home Reference (NIH)XCR1
Genomic and cartography
GoldenPath hg38 (UCSC)XCR1  -     chr3:46020799-46027487 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)XCR1  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblXCR1 - 3p21.31 [CytoView hg19]  XCR1 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBIXCR1 [Mapview hg19]  XCR1 [Mapview hg38]
OMIM600552   
Gene and transcription
Genbank (Entrez)AB189434 AB189435 AK092973 AK314277 BC069075
RefSeq transcript (Entrez)NM_001024644 NM_005283
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)XCR1
Cluster EST : UnigeneHs.248116 [ NCBI ]
CGAP (NCI)Hs.248116
Alternative Splicing GalleryENSG00000173578
Gene ExpressionXCR1 [ NCBI-GEO ]   XCR1 [ EBI - ARRAY_EXPRESS ]   XCR1 [ SEEK ]   XCR1 [ MEM ]
Gene Expression Viewer (FireBrowse)XCR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2829
GTEX Portal (Tissue expression)XCR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46094   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46094  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46094
Splice isoforms : SwissVarP46094
PhosPhoSitePlusP46094
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Chemokine_XCR1    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)XCR1
DMDM Disease mutations2829
Blocks (Seattle)XCR1
SuperfamilyP46094
Human Protein AtlasENSG00000173578
Peptide AtlasP46094
HPRD02774
IPIIPI00004349   IPI00925948   
Protein Interaction databases
DIP (DOE-UCLA)P46094
IntAct (EBI)P46094
FunCoupENSG00000173578
BioGRIDXCR1
STRING (EMBL)XCR1
ZODIACXCR1
Ontologies - Pathways
QuickGOP46094
Ontology : AmiGOchemokine receptor activity  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  G-protein coupled receptor signaling pathway  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  positive regulation of cytosolic calcium ion concentration  chemokine-mediated signaling pathway  
Ontology : EGO-EBIchemokine receptor activity  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  G-protein coupled receptor signaling pathway  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  positive regulation of cytosolic calcium ion concentration  chemokine-mediated signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkXCR1
Atlas of Cancer Signalling NetworkXCR1
Wikipedia pathwaysXCR1
Orthology - Evolution
OrthoDB2829
GeneTree (enSembl)ENSG00000173578
Phylogenetic Trees/Animal Genes : TreeFamXCR1
HOVERGENP46094
HOGENOMP46094
Homologs : HomoloGeneXCR1
Homology/Alignments : Family Browser (UCSC)XCR1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerXCR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)XCR1
dbVarXCR1
ClinVarXCR1
1000_GenomesXCR1 
Exome Variant ServerXCR1
ExAC (Exome Aggregation Consortium)XCR1 (select the gene name)
Genetic variants : HAPMAP2829
Genomic Variants (DGV)XCR1 [DGVbeta]
DECIPHERXCR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisXCR1 
Mutations
ICGC Data PortalXCR1 
TCGA Data PortalXCR1 
Broad Tumor PortalXCR1
OASIS PortalXCR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICXCR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDXCR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch XCR1
DgiDB (Drug Gene Interaction Database)XCR1
DoCM (Curated mutations)XCR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)XCR1 (select a term)
intoGenXCR1
Cancer3DXCR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600552   
Orphanet
MedgenXCR1
Genetic Testing Registry XCR1
NextProtP46094 [Medical]
TSGene2829
GENETestsXCR1
Target ValidationXCR1
Huge Navigator XCR1 [HugePedia]
snp3D : Map Gene to Disease2829
BioCentury BCIQXCR1
ClinGenXCR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2829
Chemical/Pharm GKB GenePA35037
Clinical trialXCR1
Miscellaneous
canSAR (ICR)XCR1 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineXCR1
EVEXXCR1
GoPubMedXCR1
iHOPXCR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:03:02 CEST 2017

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