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XPNPEP1 (X-prolyl aminopeptidase 1)

Identity

Alias (NCBI)APP1
SAMP
XPNPEP
XPNPEPL
XPNPEPL1
HGNC (Hugo) XPNPEP1
HGNC Alias nameXaa-Pro aminopeptidase 1
HGNC Previous nameXPNPEP
 XPNPEPL1
 XPNPEPL
HGNC Previous nameX-prolyl aminopeptidase (aminopeptidase P)-like
 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
LocusID (NCBI) 7511
Atlas_Id 75790
Location 10q25.1  [Link to chromosome band 10q25]
Location_base_pair Starts at 109864766 and ends at 109923511 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADD3 (10q25.1) / XPNPEP1 (10q25.1)MALAT1 (11q13.1) / XPNPEP1 (10q25.1)XPNPEP1 (10q25.1) / ABCC1 (16p13.11)
XPNPEP1 (10q25.1) / CHI3L1 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)XPNPEP1   12822
Cards
Entrez_Gene (NCBI)XPNPEP1    X-prolyl aminopeptidase 1
AliasesAPP1; SAMP; XPNPEP; XPNPEPL; 
XPNPEPL1
GeneCards (Weizmann)XPNPEP1
Ensembl hg19 (Hinxton)ENSG00000108039 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108039 [Gene_View]  ENSG00000108039 [Sequence]  chr10:109864766-109923511 [Contig_View]  XPNPEP1 [Vega]
ICGC DataPortalENSG00000108039
TCGA cBioPortalXPNPEP1
AceView (NCBI)XPNPEP1
Genatlas (Paris)XPNPEP1
SOURCE (Princeton)XPNPEP1
Genetics Home Reference (NIH)XPNPEP1
Genomic and cartography
GoldenPath hg38 (UCSC)XPNPEP1  -     chr10:109864766-109923511 -  10q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)XPNPEP1  -     10q25.1   [Description]    (hg19-Feb_2009)
GoldenPathXPNPEP1 - 10q25.1 [CytoView hg19]  XPNPEP1 - 10q25.1 [CytoView hg38]
ImmunoBaseENSG00000108039
Genome Data Viewer NCBIXPNPEP1 [Mapview hg19]  
OMIM602443   
Gene and transcription
Genbank (Entrez)AF195530 AF272981 AK093693 AK094900 AK095447
RefSeq transcript (Entrez)NM_001167604 NM_001324128 NM_001324131 NM_001324132 NM_001324133 NM_001324134 NM_001324135 NM_001324136 NM_020383
Consensus coding sequences : CCDS (NCBI)XPNPEP1
Gene ExpressionXPNPEP1 [ NCBI-GEO ]   XPNPEP1 [ EBI - ARRAY_EXPRESS ]   XPNPEP1 [ SEEK ]   XPNPEP1 [ MEM ]
Gene Expression Viewer (FireBrowse)XPNPEP1 [ Firebrowse - Broad ]
GenevisibleExpression of XPNPEP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7511
GTEX Portal (Tissue expression)XPNPEP1
Human Protein AtlasENSG00000108039-XPNPEP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQW7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQW7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQW7
Catalytic activity : Enzyme3.4.11.9 [ Enzyme-Expasy ]   3.4.11.93.4.11.9 [ IntEnz-EBI ]   3.4.11.9 [ BRENDA ]   3.4.11.9 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9NQW7
Domaine pattern : Prosite (Expaxy)PROLINE_PEPTIDASE (PS00491)   
Domains : Interpro (EBI)Creatin/AminoP/Spt16_NTD    Creatinase/aminopeptidase-like    Creatinase_N    Pept_M24    Pept_M24B    Peptidase_M24_C    Peptidase_M24B_aminopep-P_CS   
Domain families : Pfam (Sanger)Creatinase_N (PF01321)    Peptidase_M24 (PF00557)    Peptidase_M24_C (PF16188)   
Domain families : Pfam (NCBI)pfam01321    pfam00557    pfam16188   
Conserved Domain (NCBI)XPNPEP1
PDB (RSDB)3CTZ   
PDB Europe3CTZ   
PDB (PDBSum)3CTZ   
PDB (IMB)3CTZ   
Structural Biology KnowledgeBase3CTZ   
SCOP (Structural Classification of Proteins)3CTZ   
CATH (Classification of proteins structures)3CTZ   
SuperfamilyQ9NQW7
AlphaFold pdb e-kbQ9NQW7   
Human Protein Atlas [tissue]ENSG00000108039-XPNPEP1 [tissue]
HPRD03899
Protein Interaction databases
DIP (DOE-UCLA)Q9NQW7
IntAct (EBI)Q9NQW7
BioGRIDXPNPEP1
STRING (EMBL)XPNPEP1
ZODIACXPNPEP1
Ontologies - Pathways
QuickGOQ9NQW7
Ontology : AmiGOaminopeptidase activity  cytoplasm  cytosol  proteolysis  bradykinin catabolic process  manganese ion binding  protein homodimerization activity  metalloaminopeptidase activity  extracellular exosome  
Ontology : EGO-EBIaminopeptidase activity  cytoplasm  cytosol  proteolysis  bradykinin catabolic process  manganese ion binding  protein homodimerization activity  metalloaminopeptidase activity  extracellular exosome  
NDEx NetworkXPNPEP1
Atlas of Cancer Signalling NetworkXPNPEP1
Wikipedia pathwaysXPNPEP1
Orthology - Evolution
OrthoDB7511
GeneTree (enSembl)ENSG00000108039
Phylogenetic Trees/Animal Genes : TreeFamXPNPEP1
Homologs : HomoloGeneXPNPEP1
Homology/Alignments : Family Browser (UCSC)XPNPEP1
Gene fusions - Rearrangements
Fusion : QuiverXPNPEP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerXPNPEP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)XPNPEP1
dbVarXPNPEP1
ClinVarXPNPEP1
MonarchXPNPEP1
1000_GenomesXPNPEP1 
Exome Variant ServerXPNPEP1
GNOMAD BrowserENSG00000108039
Varsome BrowserXPNPEP1
ACMGXPNPEP1 variants
VarityQ9NQW7
Genomic Variants (DGV)XPNPEP1 [DGVbeta]
DECIPHERXPNPEP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisXPNPEP1 
Mutations
ICGC Data PortalXPNPEP1 
TCGA Data PortalXPNPEP1 
Broad Tumor PortalXPNPEP1
OASIS PortalXPNPEP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICXPNPEP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DXPNPEP1
Mutations and Diseases : HGMDXPNPEP1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaXPNPEP1
DgiDB (Drug Gene Interaction Database)XPNPEP1
DoCM (Curated mutations)XPNPEP1
CIViC (Clinical Interpretations of Variants in Cancer)XPNPEP1
Cancer3DXPNPEP1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602443   
Orphanet
DisGeNETXPNPEP1
MedgenXPNPEP1
Genetic Testing Registry XPNPEP1
NextProtQ9NQW7 [Medical]
GENETestsXPNPEP1
Target ValidationXPNPEP1
Huge Navigator XPNPEP1 [HugePedia]
ClinGenXPNPEP1
Clinical trials, drugs, therapy
MyCancerGenomeXPNPEP1
Protein Interactions : CTDXPNPEP1
Pharm GKB GenePA37415
PharosQ9NQW7
Clinical trialXPNPEP1
Miscellaneous
canSAR (ICR)XPNPEP1
HarmonizomeXPNPEP1
DataMed IndexXPNPEP1
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXXPNPEP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:28:40 CEST 2021

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