Atlas of Genetics and Cytogenetics in Oncology and Haematology


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XPO6 (exportin 6)

Identity

Alias_namesRANBP20
RAN binding protein 20
Alias_symbol (synonym)KIAA0370
FLJ22519
Other aliasEXP6
HGNC (Hugo) XPO6
LocusID (NCBI) 23214
Atlas_Id 56619
Location 16p12.1  [Link to chromosome band 16p12]
Location_base_pair Starts at 28097976 and ends at 28211918 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MPV17L (16p13.11) / XPO6 (16p11.2)PCSK7 (11q23.3) / XPO6 (16p11.2)XPO6 (16p11.2) / AKAP13 (15q25.3)
XPO6 (16p11.2) / DRC3 (17p11.2)XPO6 (16p11.2) / NCOA3 (20q13.12)XPO6 (16p11.2) / TXNDC16 (14q22.1)
XPO6 (16p11.2) / XPO6 (16p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)XPO6   19733
Cards
Entrez_Gene (NCBI)XPO6  23214  exportin 6
AliasesEXP6; RANBP20
GeneCards (Weizmann)XPO6
Ensembl hg19 (Hinxton)ENSG00000169180 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169180 [Gene_View]  chr16:28097976-28211918 [Contig_View]  XPO6 [Vega]
ICGC DataPortalENSG00000169180
TCGA cBioPortalXPO6
AceView (NCBI)XPO6
Genatlas (Paris)XPO6
WikiGenes23214
SOURCE (Princeton)XPO6
Genetics Home Reference (NIH)XPO6
Genomic and cartography
GoldenPath hg38 (UCSC)XPO6  -     chr16:28097976-28211918 -  16p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)XPO6  -     16p12.1   [Description]    (hg19-Feb_2009)
EnsemblXPO6 - 16p12.1 [CytoView hg19]  XPO6 - 16p12.1 [CytoView hg38]
Mapping of homologs : NCBIXPO6 [Mapview hg19]  XPO6 [Mapview hg38]
OMIM608411   
Gene and transcription
Genbank (Entrez)AB002368 AK026172 AK123846 AK223043 AY026388
RefSeq transcript (Entrez)NM_001270940 NM_015171
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)XPO6
Cluster EST : UnigeneHs.460468 [ NCBI ]
CGAP (NCI)Hs.460468
Alternative Splicing GalleryENSG00000169180
Gene ExpressionXPO6 [ NCBI-GEO ]   XPO6 [ EBI - ARRAY_EXPRESS ]   XPO6 [ SEEK ]   XPO6 [ MEM ]
Gene Expression Viewer (FireBrowse)XPO6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23214
GTEX Portal (Tissue expression)XPO6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96QU8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96QU8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96QU8
Splice isoforms : SwissVarQ96QU8
PhosPhoSitePlusQ96QU8
Domaine pattern : Prosite (Expaxy)IMPORTIN_B_NT (PS50166)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Exportin-1/Importin-b-like    Importin-beta_N   
Domain families : Pfam (Sanger)IBN_N (PF03810)    Xpo1 (PF08389)   
Domain families : Pfam (NCBI)pfam03810    pfam08389   
Domain families : Smart (EMBL)IBN_N (SM00913)  
Conserved Domain (NCBI)XPO6
DMDM Disease mutations23214
Blocks (Seattle)XPO6
SuperfamilyQ96QU8
Human Protein AtlasENSG00000169180
Peptide AtlasQ96QU8
HPRD10525
IPIIPI00465296   
Protein Interaction databases
DIP (DOE-UCLA)Q96QU8
IntAct (EBI)Q96QU8
FunCoupENSG00000169180
BioGRIDXPO6
STRING (EMBL)XPO6
ZODIACXPO6
Ontologies - Pathways
QuickGOQ96QU8
Ontology : AmiGOprotein binding  nucleus  nucleus  nucleolus  cytoplasm  cytosol  plasma membrane  protein export from nucleus  Ran GTPase binding  protein transporter activity  
Ontology : EGO-EBIprotein binding  nucleus  nucleus  nucleolus  cytoplasm  cytosol  plasma membrane  protein export from nucleus  Ran GTPase binding  protein transporter activity  
NDEx NetworkXPO6
Atlas of Cancer Signalling NetworkXPO6
Wikipedia pathwaysXPO6
Orthology - Evolution
OrthoDB23214
GeneTree (enSembl)ENSG00000169180
Phylogenetic Trees/Animal Genes : TreeFamXPO6
HOVERGENQ96QU8
HOGENOMQ96QU8
Homologs : HomoloGeneXPO6
Homology/Alignments : Family Browser (UCSC)XPO6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerXPO6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)XPO6
dbVarXPO6
ClinVarXPO6
1000_GenomesXPO6 
Exome Variant ServerXPO6
ExAC (Exome Aggregation Consortium)XPO6 (select the gene name)
Genetic variants : HAPMAP23214
Genomic Variants (DGV)XPO6 [DGVbeta]
DECIPHERXPO6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisXPO6 
Mutations
ICGC Data PortalXPO6 
TCGA Data PortalXPO6 
Broad Tumor PortalXPO6
OASIS PortalXPO6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICXPO6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDXPO6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch XPO6
DgiDB (Drug Gene Interaction Database)XPO6
DoCM (Curated mutations)XPO6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)XPO6 (select a term)
intoGenXPO6
Cancer3DXPO6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608411   
Orphanet
MedgenXPO6
Genetic Testing Registry XPO6
NextProtQ96QU8 [Medical]
TSGene23214
GENETestsXPO6
Target ValidationXPO6
Huge Navigator XPO6 [HugePedia]
snp3D : Map Gene to Disease23214
BioCentury BCIQXPO6
ClinGenXPO6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23214
Chemical/Pharm GKB GenePA134989996
Clinical trialXPO6
Miscellaneous
canSAR (ICR)XPO6 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineXPO6
EVEXXPO6
GoPubMedXPO6
iHOPXPO6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 13:03:04 CEST 2017

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