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XPR1 (xenotropic and polytropic retrovirus receptor 1)

Identity

Other namesIBGC6
SYG1
X3
HGNC (Hugo) XPR1
LocusID (NCBI) 9213
Atlas_Id 42846
Location 1q25.3
Location_base_pair Starts at 180601146 and ends at 180859415 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2015)
RFWD2 1q25.1 / XPR1 1q25.3XPR1 1q25.3 FAM5CXPR1 1q25.3 / KIFAP3 1q24.2
XPR1 1q25.3 / RFWD2 1q25.1XPR1 1q25.3 / TOR3A 1q25.2XPR1 1q25.3 / TYW3 1p31.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas)
  Lung: Translocations in Small Cell Carcinoma

External links

Nomenclature
HGNC (Hugo)XPR1   12827
Cards
Entrez_Gene (NCBI)XPR1  9213  xenotropic and polytropic retrovirus receptor 1
GeneCards (Weizmann)XPR1
Ensembl hg19 (Hinxton)ENSG00000143324 [Gene_View]  chr1:180601146-180859415 [Contig_View]  XPR1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143324 [Gene_View]  chr1:180601146-180859415 [Contig_View]  XPR1 [Vega]
ICGC DataPortalENSG00000143324
TCGA cBioPortalXPR1
AceView (NCBI)XPR1
Genatlas (Paris)XPR1
WikiGenes9213
SOURCE (Princeton)XPR1
Genomic and cartography
GoldenPath hg19 (UCSC)XPR1  -     chr1:180601146-180859415 +  1q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)XPR1  -     1q25.3   [Description]    (hg38-Dec_2013)
EnsemblXPR1 - 1q25.3 [CytoView hg19]  XPR1 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBIXPR1 [Mapview hg19]  XPR1 [Mapview hg38]
OMIM605237   616413   
Gene and transcription
Genbank (Entrez)AA425354 AB075495 AF089744 AF099082 AF115389
RefSeq transcript (Entrez)NM_001135669 NM_004736
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)XPR1
Cluster EST : UnigeneHs.227656 [ NCBI ]
CGAP (NCI)Hs.227656
Alternative Splicing : Fast-db (Paris)GSHG0001239
Alternative Splicing GalleryENSG00000143324
Gene ExpressionXPR1 [ NCBI-GEO ]     XPR1 [ SEEK ]   XPR1 [ MEM ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)9213
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBH6 (Uniprot)
NextProtQ9UBH6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBH6
Splice isoforms : SwissVarQ9UBH6 (Swissvar)
PhosPhoSitePlusQ9UBH6
Domaine pattern : Prosite (Expaxy)EXS (PS51380)    SPX (PS51382)   
Domains : Interpro (EBI)EXS_C    SPX_N   
Domain families : Pfam (Sanger)EXS (PF03124)    SPX (PF03105)   
Domain families : Pfam (NCBI)pfam03124    pfam03105   
DMDM Disease mutations9213
Blocks (Seattle)XPR1
Human Protein AtlasENSG00000143324
Peptide AtlasQ9UBH6
HPRD05574
IPIIPI00295447   IPI00217110   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBH6
IntAct (EBI)Q9UBH6
FunCoupENSG00000143324
BioGRIDXPR1
IntegromeDBXPR1
STRING (EMBL)XPR1
ZODIACXPR1
Ontologies - Pathways
QuickGOQ9UBH6
Ontology : AmiGOvirus receptor activity  receptor activity  transmembrane signaling receptor activity  G-protein coupled receptor activity  Golgi apparatus  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  response to virus  cellular phosphate ion homeostasis  viral entry into host cell  
Ontology : EGO-EBIvirus receptor activity  receptor activity  transmembrane signaling receptor activity  G-protein coupled receptor activity  Golgi apparatus  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  response to virus  cellular phosphate ion homeostasis  viral entry into host cell  
Protein Interaction DatabaseXPR1
Atlas of Cancer Signalling NetworkXPR1
Wikipedia pathwaysXPR1
Orthology - Evolution
OrthoDB9213
GeneTree (enSembl)ENSG00000143324
Phylogenetic Trees/Animal Genes : TreeFamXPR1
Homologs : HomoloGeneXPR1
Homology/Alignments : Family Browser (UCSC)XPR1
Gene fusions - Rearrangements
Fusion: TCGARFWD2 1q25.1 XPR1 1q25.3 BRCA
Fusion: TCGAXPR1 1q25.3 FAM5C BRCA
Fusion: TCGAXPR1 1q25.3 KIFAP3 1q24.2 BRCA
Fusion: TCGAXPR1 1q25.3 RFWD2 1q25.1 BRCA
Fusion: TCGAXPR1 1q25.3 TOR3A 1q25.2 HNSC
Fusion: TCGAXPR1 1q25.3 TYW3 1p31.1 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerXPR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)XPR1
dbVarXPR1
ClinVarXPR1
1000_GenomesXPR1 
Exome Variant ServerXPR1
Exome Aggregation Consortium (ExAC)ENSG00000143324
SNP (GeneSNP Utah)XPR1
SNP : HGBaseXPR1
Genetic variants : HAPMAPXPR1
Genomic Variants (DGV)XPR1 [DGVbeta]
Mutations
ICGC Data PortalXPR1 
TCGA Data PortalXPR1 
Tumor PortalXPR1
TCGA Copy Number PortalXPR1
Somatic Mutations in Cancer : COSMICXPR1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch XPR1
DgiDB (Drug Gene Interaction Database)XPR1
DoCM (Curated mutations)XPR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)XPR1 (select a term)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:180601146-180859415
CONAN: Copy Number AnalysisXPR1 
Mutations and Diseases : HGMDXPR1
OMIM605237    616413   
MedgenXPR1
NextProtQ9UBH6 [Medical]
TSGene9213
GENETestsXPR1
Huge Navigator XPR1 [HugePedia]  XPR1 [HugeCancerGEM]
snp3D : Map Gene to Disease9213
BioCentury BCIQXPR1
General knowledge
Chemical/Protein Interactions : CTD9213
Chemical/Pharm GKB GenePA37420
Clinical trialXPR1
Other databases
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineXPR1
GoPubMedXPR1
iHOPXPR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jan 16 19:45:31 CET 2016

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