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YAF2 (YY1 associated factor 2)

Identity

Other alias-
HGNC (Hugo) YAF2
LocusID (NCBI) 10138
Atlas_Id 42853
Location 12q12  [Link to chromosome band 12q12]
Location_base_pair Starts at 42157105 and ends at 42238368 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ARID2 (12q12) / YAF2 (12q12)IGFBP5 (2q35) / YAF2 (12q12)YAF2 (12q12) / DMTF1 (7q21.12)
YAF2 (12q12) / SYT1 (12q21.2)YAF2 12q12 / SYT1 12q21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)YAF2   17363
Cards
Entrez_Gene (NCBI)YAF2  10138  YY1 associated factor 2
Aliases
GeneCards (Weizmann)YAF2
Ensembl hg19 (Hinxton)ENSG00000015153 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000015153 [Gene_View]  chr12:42157105-42238368 [Contig_View]  YAF2 [Vega]
ICGC DataPortalENSG00000015153
TCGA cBioPortalYAF2
AceView (NCBI)YAF2
Genatlas (Paris)YAF2
WikiGenes10138
SOURCE (Princeton)YAF2
Genetics Home Reference (NIH)YAF2
Genomic and cartography
GoldenPath hg38 (UCSC)YAF2  -     chr12:42157105-42238368 -  12q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)YAF2  -     12q12   [Description]    (hg19-Feb_2009)
EnsemblYAF2 - 12q12 [CytoView hg19]  YAF2 - 12q12 [CytoView hg38]
Mapping of homologs : NCBIYAF2 [Mapview hg19]  YAF2 [Mapview hg38]
OMIM607534   
Gene and transcription
Genbank (Entrez)AA789222 AI654632 AK127531 AK291355 AK294260
RefSeq transcript (Entrez)NM_001012424 NM_001190977 NM_001190979 NM_001190980 NM_001320080 NM_005748
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)YAF2
Cluster EST : UnigeneHs.708084 [ NCBI ]
CGAP (NCI)Hs.708084
Alternative Splicing GalleryENSG00000015153
Gene ExpressionYAF2 [ NCBI-GEO ]   YAF2 [ EBI - ARRAY_EXPRESS ]   YAF2 [ SEEK ]   YAF2 [ MEM ]
Gene Expression Viewer (FireBrowse)YAF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10138
GTEX Portal (Tissue expression)YAF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IY57   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IY57  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IY57
Splice isoforms : SwissVarQ8IY57
PhosPhoSitePlusQ8IY57
Domaine pattern : Prosite (Expaxy)ZF_RANBP2_1 (PS01358)    ZF_RANBP2_2 (PS50199)   
Domains : Interpro (EBI)YAF2_RYBP    Znf_RanBP2   
Domain families : Pfam (Sanger)YAF2_RYBP (PF17219)    zf-RanBP (PF00641)   
Domain families : Pfam (NCBI)pfam17219    pfam00641   
Domain families : Smart (EMBL)ZnF_RBZ (SM00547)  
Conserved Domain (NCBI)YAF2
DMDM Disease mutations10138
Blocks (Seattle)YAF2
PDB (SRS)2D9G   
PDB (PDBSum)2D9G   
PDB (IMB)2D9G   
PDB (RSDB)2D9G   
Structural Biology KnowledgeBase2D9G   
SCOP (Structural Classification of Proteins)2D9G   
CATH (Classification of proteins structures)2D9G   
SuperfamilyQ8IY57
Human Protein AtlasENSG00000015153
Peptide AtlasQ8IY57
HPRD09606
IPIIPI00024740   IPI00377181   IPI00552541   IPI01021650   IPI01021495   IPI01022493   IPI01021145   IPI00792546   IPI01022619   IPI01022764   IPI00982093   IPI00908736   IPI01025956   
Protein Interaction databases
DIP (DOE-UCLA)Q8IY57
IntAct (EBI)Q8IY57
FunCoupENSG00000015153
BioGRIDYAF2
STRING (EMBL)YAF2
ZODIACYAF2
Ontologies - Pathways
QuickGOQ8IY57
Ontology : AmiGOtranscription coactivator activity  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytosol  transcription, DNA-templated  zinc ion binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  
Ontology : EGO-EBItranscription coactivator activity  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytosol  transcription, DNA-templated  zinc ion binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  
NDEx NetworkYAF2
Atlas of Cancer Signalling NetworkYAF2
Wikipedia pathwaysYAF2
Orthology - Evolution
OrthoDB10138
GeneTree (enSembl)ENSG00000015153
Phylogenetic Trees/Animal Genes : TreeFamYAF2
HOVERGENQ8IY57
HOGENOMQ8IY57
Homologs : HomoloGeneYAF2
Homology/Alignments : Family Browser (UCSC)YAF2
Gene fusions - Rearrangements
Fusion : MitelmanYAF2/SYT1 [12q12/12q21.2]  
Fusion: TCGAYAF2 12q12 SYT1 12q21.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerYAF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)YAF2
dbVarYAF2
ClinVarYAF2
1000_GenomesYAF2 
Exome Variant ServerYAF2
ExAC (Exome Aggregation Consortium)YAF2 (select the gene name)
Genetic variants : HAPMAP10138
Genomic Variants (DGV)YAF2 [DGVbeta]
DECIPHERYAF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisYAF2 
Mutations
ICGC Data PortalYAF2 
TCGA Data PortalYAF2 
Broad Tumor PortalYAF2
OASIS PortalYAF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICYAF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDYAF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch YAF2
DgiDB (Drug Gene Interaction Database)YAF2
DoCM (Curated mutations)YAF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)YAF2 (select a term)
intoGenYAF2
Cancer3DYAF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607534   
Orphanet
MedgenYAF2
Genetic Testing Registry YAF2
NextProtQ8IY57 [Medical]
TSGene10138
GENETestsYAF2
Huge Navigator YAF2 [HugePedia]
snp3D : Map Gene to Disease10138
BioCentury BCIQYAF2
ClinGenYAF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10138
Chemical/Pharm GKB GenePA38236
Clinical trialYAF2
Miscellaneous
canSAR (ICR)YAF2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineYAF2
EVEXYAF2
GoPubMedYAF2
iHOPYAF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:44:25 CEST 2017

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