YIPF5 (Yip1 domain family member 5)

2007-02-01  

Identity

HGNC
YIPF5
LOCATION
5q31.3
LOCUSID
81555
ALIAS
FinGER5,MEDS2,SB140,SMAP-5,SMAP5,YIP1A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81555
MIM: 611483
HGNC: 24877
Ensembl: ENSG00000145817

Variants:

dbSNP: 81555
ClinVar: 81555
TCGA: ENSG00000145817
COSMIC: YIPF5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145817ENST00000274496Q969M3
ENSG00000145817ENST00000448443Q969M3
ENSG00000145817ENST00000513112Q969M3
ENSG00000145817ENST00000519064E5RHH4
ENSG00000145817ENST00000522203E5RGR9

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
257421382015Yip1A, a novel host factor for the activation of the IRE1 pathway of the unfolded protein response during Brucella infection.22
195090592009Yip1A regulates the COPI-independent retrograde transport from the Golgi complex to the ER.16
187184662008YIPF5 and YIF1A recycle between the ER and the Golgi apparatus and are involved in the maintenance of the Golgi structure.14
202371552010Yip1A structures the mammalian endoplasmic reticulum.14
159900862005Human Yip1A specifies the localization of Yif1 to the Golgi apparatus.7
159228702005Cloning, cellular localization, genomic organization, and tissue-specific expression of the TGFbeta1-inducible SMAP-5 gene.4
279999942017Functional characterisation of the YIPF protein family in mammalian cells.4
198458952009Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations.3
233421552013Identification of discrete sites in Yip1A necessary for regulation of endoplasmic reticulum structure.3
313912322019YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking.1

Citation

Dessen P

YIPF5 (Yip1 domain family member 5)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46103/yipf5