Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

YME1L1 (YME1 like 1 ATPase)

Identity

Alias_namesYME1 (S.cerevisiae)-like 1
YME1-like 1 (S. cerevisiae)
YME1-like 1 ATPase
Other aliasFTSH
MEG4
PAMP
YME1L
HGNC (Hugo) YME1L1
LocusID (NCBI) 10730
Atlas_Id 56105
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 27399040 and ends at 27443349 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ABI1 (10p12.1) / YME1L1 (10p12.1)AHCYL2 (7q32.1) / YME1L1 (10p12.1)LUC7L (16p13.3) / YME1L1 (10p12.1)
YME1L1 (10p12.1) / BRD8 (5q31.2)YME1L1 (10p12.1) / RTN1 (14q23.1)YME1L1 (10p12.1) / SLC35D2 (9q22.32)
YME1L1 (10p12.1) / ZNF880 (19q13.41)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)YME1L1   12843
Cards
Entrez_Gene (NCBI)YME1L1  10730  YME1 like 1 ATPase
AliasesFTSH; MEG4; PAMP; YME1L
GeneCards (Weizmann)YME1L1
Ensembl hg19 (Hinxton)ENSG00000136758 [Gene_View]  chr10:27399040-27443349 [Contig_View]  YME1L1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000136758 [Gene_View]  chr10:27399040-27443349 [Contig_View]  YME1L1 [Vega]
ICGC DataPortalENSG00000136758
TCGA cBioPortalYME1L1
AceView (NCBI)YME1L1
Genatlas (Paris)YME1L1
WikiGenes10730
SOURCE (Princeton)YME1L1
Genetics Home Reference (NIH)YME1L1
Genomic and cartography
GoldenPath hg19 (UCSC)YME1L1  -     chr10:27399040-27443349 -  10p12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)YME1L1  -     10p12.1   [Description]    (hg38-Dec_2013)
EnsemblYME1L1 - 10p12.1 [CytoView hg19]  YME1L1 - 10p12.1 [CytoView hg38]
Mapping of homologs : NCBIYME1L1 [Mapview hg19]  YME1L1 [Mapview hg38]
OMIM607472   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001253866 NM_014263 NM_139312 NM_139313
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)YME1L1
Cluster EST : UnigeneHs.499145 [ NCBI ]
CGAP (NCI)Hs.499145
Alternative Splicing GalleryENSG00000136758
Gene ExpressionYME1L1 [ NCBI-GEO ]   YME1L1 [ EBI - ARRAY_EXPRESS ]   YME1L1 [ SEEK ]   YME1L1 [ MEM ]
Gene Expression Viewer (FireBrowse)YME1L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10730
GTEX Portal (Tissue expression)YME1L1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96TA2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96TA2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96TA2
Splice isoforms : SwissVarQ96TA2
Catalytic activity : Enzyme3.4.24.- [ Enzyme-Expasy ]   3.4.24.-3.4.24.- [ IntEnz-EBI ]   3.4.24.- [ BRENDA ]   3.4.24.- [ KEGG ]   
PhosPhoSitePlusQ96TA2
Domaine pattern : Prosite (Expaxy)AAA (PS00674)   
Domains : Interpro (EBI)AAA+_ATPase    ATPase_AAA_core    ATPase_AAA_CS    FtsH    P-loop_NTPase    Peptidase_M41   
Domain families : Pfam (Sanger)AAA (PF00004)    Peptidase_M41 (PF01434)   
Domain families : Pfam (NCBI)pfam00004    pfam01434   
Domain families : Smart (EMBL)AAA (SM00382)  
Conserved Domain (NCBI)YME1L1
DMDM Disease mutations10730
Blocks (Seattle)YME1L1
SuperfamilyQ96TA2
Human Protein AtlasENSG00000136758
Peptide AtlasQ96TA2
HPRD06981
IPIIPI00045946   IPI00099529   IPI00513860   IPI01014200   IPI00448921   IPI01015575   IPI00645379   
Protein Interaction databases
DIP (DOE-UCLA)Q96TA2
IntAct (EBI)Q96TA2
FunCoupENSG00000136758
BioGRIDYME1L1
STRING (EMBL)YME1L1
ZODIACYME1L1
Ontologies - Pathways
QuickGOQ96TA2
Ontology : AmiGOATP-dependent peptidase activity  metalloendopeptidase activity  ATP binding  nucleoplasm  mitochondrion  mitochondrial inner membrane  misfolded or incompletely synthesized protein catabolic process  mitochondrion organization  metallopeptidase activity  cell proliferation  membrane  integral component of membrane  mitochondrial protein catabolic process  metal ion binding  
Ontology : EGO-EBIATP-dependent peptidase activity  metalloendopeptidase activity  ATP binding  nucleoplasm  mitochondrion  mitochondrial inner membrane  misfolded or incompletely synthesized protein catabolic process  mitochondrion organization  metallopeptidase activity  cell proliferation  membrane  integral component of membrane  mitochondrial protein catabolic process  metal ion binding  
NDEx NetworkYME1L1
Atlas of Cancer Signalling NetworkYME1L1
Wikipedia pathwaysYME1L1
Orthology - Evolution
OrthoDB10730
GeneTree (enSembl)ENSG00000136758
Phylogenetic Trees/Animal Genes : TreeFamYME1L1
HOVERGENQ96TA2
HOGENOMQ96TA2
Homologs : HomoloGeneYME1L1
Homology/Alignments : Family Browser (UCSC)YME1L1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerYME1L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)YME1L1
dbVarYME1L1
ClinVarYME1L1
1000_GenomesYME1L1 
Exome Variant ServerYME1L1
ExAC (Exome Aggregation Consortium)YME1L1 (select the gene name)
Genetic variants : HAPMAP10730
Genomic Variants (DGV)YME1L1 [DGVbeta]
DECIPHER (Syndromes)10:27399040-27443349  ENSG00000136758
CONAN: Copy Number AnalysisYME1L1 
Mutations
ICGC Data PortalYME1L1 
TCGA Data PortalYME1L1 
Broad Tumor PortalYME1L1
OASIS PortalYME1L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICYME1L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDYME1L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch YME1L1
DgiDB (Drug Gene Interaction Database)YME1L1
DoCM (Curated mutations)YME1L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)YME1L1 (select a term)
intoGenYME1L1
Cancer3DYME1L1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607472   
Orphanet
MedgenYME1L1
Genetic Testing Registry YME1L1
NextProtQ96TA2 [Medical]
TSGene10730
GENETestsYME1L1
Huge Navigator YME1L1 [HugePedia]
snp3D : Map Gene to Disease10730
BioCentury BCIQYME1L1
ClinGenYME1L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10730
Chemical/Pharm GKB GenePA37434
Clinical trialYME1L1
Miscellaneous
canSAR (ICR)YME1L1 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineYME1L1
EVEXYME1L1
GoPubMedYME1L1
iHOPYME1L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:25:18 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.