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YOD1 (YOD1 deubiquitinase)

Identity

Alias (NCBI)DUBA8
OTUD2
PRO0907
HGNC (Hugo) YOD1
HGNC Alias symbDKFZp451J1719
OTUD2
DUBA8
HGNC Previous nameYOD1 OTU deubiquinating enzyme 1 homolog ( yeast)
 YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
LocusID (NCBI) 55432
Atlas_Id 55350
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 207043849 and ends at 207051077 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)YOD1   25035
Cards
Entrez_Gene (NCBI)YOD1    YOD1 deubiquitinase
AliasesDUBA8; OTUD2; PRO0907
GeneCards (Weizmann)YOD1
Ensembl hg19 (Hinxton)ENSG00000180667 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180667 [Gene_View]  ENSG00000180667 [Sequence]  chr1:207043849-207051077 [Contig_View]  YOD1 [Vega]
ICGC DataPortalENSG00000180667
TCGA cBioPortalYOD1
AceView (NCBI)YOD1
Genatlas (Paris)YOD1
SOURCE (Princeton)YOD1
Genetics Home Reference (NIH)YOD1
Genomic and cartography
GoldenPath hg38 (UCSC)YOD1  -     chr1:207043849-207051077 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)YOD1  -     1q32.1   [Description]    (hg19-Feb_2009)
GoldenPathYOD1 - 1q32.1 [CytoView hg19]  YOD1 - 1q32.1 [CytoView hg38]
ImmunoBaseENSG00000180667
genome Data Viewer NCBIYOD1 [Mapview hg19]  
OMIM612023   
Gene and transcription
Genbank (Entrez)AK128014 AL833081 BC137166 BC137167
RefSeq transcript (Entrez)NM_001276320 NM_018566
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)YOD1
Alternative Splicing GalleryENSG00000180667
Gene ExpressionYOD1 [ NCBI-GEO ]   YOD1 [ EBI - ARRAY_EXPRESS ]   YOD1 [ SEEK ]   YOD1 [ MEM ]
Gene Expression Viewer (FireBrowse)YOD1 [ Firebrowse - Broad ]
GenevisibleExpression of YOD1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55432
GTEX Portal (Tissue expression)YOD1
Human Protein AtlasENSG00000180667-YOD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VVQ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VVQ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VVQ6
Splice isoforms : SwissVarQ5VVQ6
PhosPhoSitePlusQ5VVQ6
Domaine pattern : Prosite (Expaxy)OTU (PS50802)    ZINC_FINGER_C2H2_1 (PS00028)   
Domains : Interpro (EBI)OTU1_2_3    OTU_dom    Papain-like_cys_pep_sf    Ubiquitin-like_domsf    Znf_C2H2_type   
Domain families : Pfam (Sanger)OTU (PF02338)   
Domain families : Pfam (NCBI)pfam02338   
Conserved Domain (NCBI)YOD1
Blocks (Seattle)YOD1
PDB (RSDB)4BOQ    4BOS    4BOZ   
PDB Europe4BOQ    4BOS    4BOZ   
PDB (PDBSum)4BOQ    4BOS    4BOZ   
PDB (IMB)4BOQ    4BOS    4BOZ   
Structural Biology KnowledgeBase4BOQ    4BOS    4BOZ   
SCOP (Structural Classification of Proteins)4BOQ    4BOS    4BOZ   
CATH (Classification of proteins structures)4BOQ    4BOS    4BOZ   
SuperfamilyQ5VVQ6
Human Protein Atlas [tissue]ENSG00000180667-YOD1 [tissue]
Peptide AtlasQ5VVQ6
HPRD10312
IPIIPI00183503   IPI00644473   
Protein Interaction databases
DIP (DOE-UCLA)Q5VVQ6
IntAct (EBI)Q5VVQ6
BioGRIDYOD1
STRING (EMBL)YOD1
ZODIACYOD1
Ontologies - Pathways
QuickGOQ5VVQ6
Ontology : AmiGOthiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  protein binding  cytoplasm  cytosol  cytosol  cysteine-type peptidase activity  macroautophagy  protein deubiquitination  protein deubiquitination  protein phosphopantetheinylation  ubiquitin-dependent ERAD pathway  ubiquitin-dependent ERAD pathway  endoplasmic reticulum unfolded protein response  endoplasmic reticulum unfolded protein response  ubiquitin protein ligase binding  protein K29-linked deubiquitination  protein K11-linked deubiquitination  protein K11-linked deubiquitination  metal ion binding  Lys63-specific deubiquitinase activity  protein K63-linked deubiquitination  protein K63-linked deubiquitination  protein K48-linked deubiquitination  protein K48-linked deubiquitination  ubiquitinyl hydrolase activity  negative regulation of retrograde protein transport, ER to cytosol  protein K27-linked deubiquitination  protein K33-linked deubiquitination  Lys48-specific deubiquitinase activity  
Ontology : EGO-EBIthiol-dependent ubiquitin-specific protease activity  thiol-dependent ubiquitin-specific protease activity  protein binding  cytoplasm  cytosol  cytosol  cysteine-type peptidase activity  macroautophagy  protein deubiquitination  protein deubiquitination  protein phosphopantetheinylation  ubiquitin-dependent ERAD pathway  ubiquitin-dependent ERAD pathway  endoplasmic reticulum unfolded protein response  endoplasmic reticulum unfolded protein response  ubiquitin protein ligase binding  protein K29-linked deubiquitination  protein K11-linked deubiquitination  protein K11-linked deubiquitination  metal ion binding  Lys63-specific deubiquitinase activity  protein K63-linked deubiquitination  protein K63-linked deubiquitination  protein K48-linked deubiquitination  protein K48-linked deubiquitination  ubiquitinyl hydrolase activity  negative regulation of retrograde protein transport, ER to cytosol  protein K27-linked deubiquitination  protein K33-linked deubiquitination  Lys48-specific deubiquitinase activity  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkYOD1
Atlas of Cancer Signalling NetworkYOD1
Wikipedia pathwaysYOD1
Orthology - Evolution
OrthoDB55432
GeneTree (enSembl)ENSG00000180667
Phylogenetic Trees/Animal Genes : TreeFamYOD1
HOGENOMQ5VVQ6
Homologs : HomoloGeneYOD1
Homology/Alignments : Family Browser (UCSC)YOD1
Gene fusions - Rearrangements
Fusion : QuiverYOD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerYOD1 [hg38]
dbVarYOD1
ClinVarYOD1
MonarchYOD1
1000_GenomesYOD1 
Exome Variant ServerYOD1
GNOMAD BrowserENSG00000180667
Varsome BrowserYOD1
Genomic Variants (DGV)YOD1 [DGVbeta]
DECIPHERYOD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisYOD1 
Mutations
ICGC Data PortalYOD1 
TCGA Data PortalYOD1 
Broad Tumor PortalYOD1
OASIS PortalYOD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICYOD1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DYOD1
Mutations and Diseases : HGMDYOD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch YOD1
DgiDB (Drug Gene Interaction Database)YOD1
DoCM (Curated mutations)YOD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)YOD1 (select a term)
intoGenYOD1
Cancer3DYOD1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612023   
Orphanet
DisGeNETYOD1
MedgenYOD1
Genetic Testing Registry YOD1
NextProtQ5VVQ6 [Medical]
GENETestsYOD1
Target ValidationYOD1
Huge Navigator YOD1 [HugePedia]
ClinGenYOD1
Clinical trials, drugs, therapy
MyCancerGenomeYOD1
Protein Interactions : CTD
Pharm GKB GenePA142670552
PharosQ5VVQ6
Clinical trialYOD1
Miscellaneous
canSAR (ICR)YOD1 (select the gene name)
HarmonizomeYOD1
DataMed IndexYOD1
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXYOD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 25 19:53:18 CET 2021

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