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YPEL1 (yippee like 1)

Identity

Alias_namesyippee (Drosophila) homolog-like 1
yippee-like 1 (Drosophila)
Other aliasFKSG3
HGNC (Hugo) YPEL1
LocusID (NCBI) 29799
Atlas_Id 42858
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 21697537 and ends at 21735834 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FANCI (15q26.1) / YPEL1 (22q11.21)SFI1 (22q12.2) / YPEL1 (22q11.21)TBC1D22B (6p21.2) / YPEL1 (22q11.21)
TBC1D22B 6p21.2 / YPEL1 22q11.21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(6;22)(p21;q11) TBC1D22B/YPEL1
t(22;22)(q11;q12) SFI1/YPEL1

External links

Nomenclature
HGNC (Hugo)YPEL1   12845
Cards
Entrez_Gene (NCBI)YPEL1  29799  yippee like 1
AliasesFKSG3
GeneCards (Weizmann)YPEL1
Ensembl hg19 (Hinxton)ENSG00000100027 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100027 [Gene_View]  ENSG00000100027 [Sequence]  chr22:21697537-21735834 [Contig_View]  YPEL1 [Vega]
ICGC DataPortalENSG00000100027
TCGA cBioPortalYPEL1
AceView (NCBI)YPEL1
Genatlas (Paris)YPEL1
WikiGenes29799
SOURCE (Princeton)YPEL1
Genetics Home Reference (NIH)YPEL1
Genomic and cartography
GoldenPath hg38 (UCSC)YPEL1  -     chr22:21697537-21735834 -  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)YPEL1  -     22q11.21   [Description]    (hg19-Feb_2009)
GoldenPathYPEL1 - 22q11.21 [CytoView hg19]  YPEL1 - 22q11.21 [CytoView hg38]
ImmunoBaseENSG00000100027
Mapping of homologs : NCBIYPEL1 [Mapview hg19]  YPEL1 [Mapview hg38]
OMIM608082   
Gene and transcription
Genbank (Entrez)AB098734 AB098735 AF060862 AF305069 AI004498
RefSeq transcript (Entrez)NM_013313
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)YPEL1
Cluster EST : UnigeneHs.517436 [ NCBI ]
CGAP (NCI)Hs.517436
Alternative Splicing GalleryENSG00000100027
Gene ExpressionYPEL1 [ NCBI-GEO ]   YPEL1 [ EBI - ARRAY_EXPRESS ]   YPEL1 [ SEEK ]   YPEL1 [ MEM ]
Gene Expression Viewer (FireBrowse)YPEL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29799
GTEX Portal (Tissue expression)YPEL1
Human Protein AtlasENSG00000100027-YPEL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60688   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60688  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60688
Splice isoforms : SwissVarO60688
PhosPhoSitePlusO60688
Domaine pattern : Prosite (Expaxy)YIPPEE (PS51792)   
Domains : Interpro (EBI)Yippee    Yippee/Mis18/Cereblon   
Domain families : Pfam (Sanger)Yippee-Mis18 (PF03226)   
Domain families : Pfam (NCBI)pfam03226   
Conserved Domain (NCBI)YPEL1
DMDM Disease mutations29799
Blocks (Seattle)YPEL1
SuperfamilyO60688
Human Protein Atlas [tissue]ENSG00000100027-YPEL1 [tissue]
Peptide AtlasO60688
HPRD16277
IPIIPI00743468   IPI00877835   
Protein Interaction databases
DIP (DOE-UCLA)O60688
IntAct (EBI)O60688
FunCoupENSG00000100027
BioGRIDYPEL1
STRING (EMBL)YPEL1
ZODIACYPEL1
Ontologies - Pathways
QuickGOO60688
Ontology : AmiGOnucleus  metal ion binding  
Ontology : EGO-EBInucleus  metal ion binding  
NDEx NetworkYPEL1
Atlas of Cancer Signalling NetworkYPEL1
Wikipedia pathwaysYPEL1
Orthology - Evolution
OrthoDB29799
GeneTree (enSembl)ENSG00000100027
Phylogenetic Trees/Animal Genes : TreeFamYPEL1
HOGENOMO60688
Homologs : HomoloGeneYPEL1
Homology/Alignments : Family Browser (UCSC)YPEL1
Gene fusions - Rearrangements
Fusion : MitelmanSFI1/YPEL1 [22q12.2/22q11.21]  [t(22;22)(q11;q12)]  
Fusion : MitelmanTBC1D22B/YPEL1 [6p21.2/22q11.21]  [t(6;22)(p21;q11)]  
Fusion PortalTBC1D22B 6p21.2 YPEL1 22q11.21 BRCA
Fusion : QuiverYPEL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerYPEL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)YPEL1
dbVarYPEL1
ClinVarYPEL1
1000_GenomesYPEL1 
Exome Variant ServerYPEL1
ExAC (Exome Aggregation Consortium)ENSG00000100027
GNOMAD BrowserENSG00000100027
Varsome BrowserYPEL1
Genetic variants : HAPMAP29799
Genomic Variants (DGV)YPEL1 [DGVbeta]
DECIPHERYPEL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisYPEL1 
Mutations
ICGC Data PortalYPEL1 
TCGA Data PortalYPEL1 
Broad Tumor PortalYPEL1
OASIS PortalYPEL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICYPEL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDYPEL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch YPEL1
DgiDB (Drug Gene Interaction Database)YPEL1
DoCM (Curated mutations)YPEL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)YPEL1 (select a term)
intoGenYPEL1
Cancer3DYPEL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608082   
Orphanet
DisGeNETYPEL1
MedgenYPEL1
Genetic Testing Registry YPEL1
NextProtO60688 [Medical]
TSGene29799
GENETestsYPEL1
Target ValidationYPEL1
Huge Navigator YPEL1 [HugePedia]
snp3D : Map Gene to Disease29799
BioCentury BCIQYPEL1
ClinGenYPEL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29799
Chemical/Pharm GKB GenePA37436
Clinical trialYPEL1
Miscellaneous
canSAR (ICR)YPEL1 (select the gene name)
DataMed IndexYPEL1
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineYPEL1
EVEXYPEL1
GoPubMedYPEL1
iHOPYPEL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 8 11:48:09 CEST 2019
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