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YTHDF3 (YTH N6-methyladenosine RNA binding protein 3)

Identity

Alias_namesYTH domain family 3
YTH domain family, member 3
YTH N(6)-methyladenosine RNA binding protein 3
Alias_symbol (synonym)FLJ31657
Other alias-
HGNC (Hugo) YTHDF3
LocusID (NCBI) 253943
Atlas_Id 75824
Location 8q12.3  [Link to chromosome band 8q12]
Location_base_pair Starts at 63168553 and ends at 63212788 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BOLA2 (16p11.2) / YTHDF3 (8q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)YTHDF3   26465
Cards
Entrez_Gene (NCBI)YTHDF3  253943  YTH N6-methyladenosine RNA binding protein 3
Aliases
GeneCards (Weizmann)YTHDF3
Ensembl hg19 (Hinxton)ENSG00000185728 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185728 [Gene_View]  chr8:63168553-63212788 [Contig_View]  YTHDF3 [Vega]
ICGC DataPortalENSG00000185728
TCGA cBioPortalYTHDF3
AceView (NCBI)YTHDF3
Genatlas (Paris)YTHDF3
WikiGenes253943
SOURCE (Princeton)YTHDF3
Genetics Home Reference (NIH)YTHDF3
Genomic and cartography
GoldenPath hg38 (UCSC)YTHDF3  -     chr8:63168553-63212788 +  8q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)YTHDF3  -     8q12.3   [Description]    (hg19-Feb_2009)
EnsemblYTHDF3 - 8q12.3 [CytoView hg19]  YTHDF3 - 8q12.3 [CytoView hg38]
Mapping of homologs : NCBIYTHDF3 [Mapview hg19]  YTHDF3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK002173 AK056219 AK093081 AK127574 AK298544
RefSeq transcript (Entrez)NM_001277813 NM_001277814 NM_001277815 NM_001277816 NM_001277817 NM_001277818 NM_152758
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)YTHDF3
Cluster EST : UnigeneHs.491861 [ NCBI ]
CGAP (NCI)Hs.491861
Alternative Splicing GalleryENSG00000185728
Gene ExpressionYTHDF3 [ NCBI-GEO ]   YTHDF3 [ EBI - ARRAY_EXPRESS ]   YTHDF3 [ SEEK ]   YTHDF3 [ MEM ]
Gene Expression Viewer (FireBrowse)YTHDF3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)253943
GTEX Portal (Tissue expression)YTHDF3
Human Protein AtlasENSG00000185728-YTHDF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z739   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z739  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z739
Splice isoforms : SwissVarQ7Z739
PhosPhoSitePlusQ7Z739
Domaine pattern : Prosite (Expaxy)YTH (PS50882)   
Domains : Interpro (EBI)YTH_domain   
Domain families : Pfam (Sanger)YTH (PF04146)   
Domain families : Pfam (NCBI)pfam04146   
Conserved Domain (NCBI)YTHDF3
DMDM Disease mutations253943
Blocks (Seattle)YTHDF3
SuperfamilyQ7Z739
Human Protein Atlas [tissue]ENSG00000185728-YTHDF3 [tissue]
Peptide AtlasQ7Z739
HPRD08106
IPIIPI00396131   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z739
IntAct (EBI)Q7Z739
FunCoupENSG00000185728
BioGRIDYTHDF3
STRING (EMBL)YTHDF3
ZODIACYTHDF3
Ontologies - Pathways
QuickGOQ7Z739
Ontology : AmiGORNA binding  protein binding  cytosol  ribosome binding  positive regulation of translation  positive regulation of translational initiation  mRNA destabilization  N6-methyladenosine-containing RNA binding  
Ontology : EGO-EBIRNA binding  protein binding  cytosol  ribosome binding  positive regulation of translation  positive regulation of translational initiation  mRNA destabilization  N6-methyladenosine-containing RNA binding  
NDEx NetworkYTHDF3
Atlas of Cancer Signalling NetworkYTHDF3
Wikipedia pathwaysYTHDF3
Orthology - Evolution
OrthoDB253943
GeneTree (enSembl)ENSG00000185728
Phylogenetic Trees/Animal Genes : TreeFamYTHDF3
HOVERGENQ7Z739
HOGENOMQ7Z739
Homologs : HomoloGeneYTHDF3
Homology/Alignments : Family Browser (UCSC)YTHDF3
Gene fusions - Rearrangements
Tumor Fusion PortalYTHDF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerYTHDF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)YTHDF3
dbVarYTHDF3
ClinVarYTHDF3
1000_GenomesYTHDF3 
Exome Variant ServerYTHDF3
ExAC (Exome Aggregation Consortium)ENSG00000185728
GNOMAD BrowserENSG00000185728
Genetic variants : HAPMAP253943
Genomic Variants (DGV)YTHDF3 [DGVbeta]
DECIPHERYTHDF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisYTHDF3 
Mutations
ICGC Data PortalYTHDF3 
TCGA Data PortalYTHDF3 
Broad Tumor PortalYTHDF3
OASIS PortalYTHDF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICYTHDF3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDYTHDF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch YTHDF3
DgiDB (Drug Gene Interaction Database)YTHDF3
DoCM (Curated mutations)YTHDF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)YTHDF3 (select a term)
intoGenYTHDF3
Cancer3DYTHDF3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETYTHDF3
MedgenYTHDF3
Genetic Testing Registry YTHDF3
NextProtQ7Z739 [Medical]
TSGene253943
GENETestsYTHDF3
Target ValidationYTHDF3
Huge Navigator YTHDF3 [HugePedia]
snp3D : Map Gene to Disease253943
BioCentury BCIQYTHDF3
ClinGenYTHDF3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD253943
Chemical/Pharm GKB GenePA134976395
Clinical trialYTHDF3
Miscellaneous
canSAR (ICR)YTHDF3 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineYTHDF3
EVEXYTHDF3
GoPubMedYTHDF3
iHOPYTHDF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Nov 21 13:19:11 CET 2017

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