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YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide)

Identity

Other names14-3-3-zeta
KCIP-1
YWHAD
HGNC (Hugo) YWHAZ
LocusID (NCBI) 7534
Location 8q22.3
Location_base_pair Starts at 101930804 and ends at 101965221 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)YWHAZ   12855
Entrez_Gene (NCBI)YWHAZ  7534  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Cards
GeneCards (Weizmann)YWHAZ
Ensembl (Hinxton)ENSG00000164924 [Gene_View]  chr8:101930804-101965221 [Contig_View]  YWHAZ [Vega]
AceView (NCBI)YWHAZ
Genatlas (Paris)YWHAZ
SOURCE (Stanford)NM_001135699 NM_001135700 NM_001135701 NM_001135702 NM_003406 NM_145690
Genomic and cartography
GoldenPath (UCSC)YWHAZ  -  8q22.3   chr8:101930804-101965221 -  8q22.3   [Description]    (hg19-Feb_2009)
EnsemblYWHAZ - 8q22.3 [CytoView]
Mapping of homologs : NCBIYWHAZ [Mapview]
OMIM601288   
Gene and transcription
Genbank (Entrez)AA830489 AK289945 AK294647 AK296902 AK307506
RefSeq transcript (SRS)NM_001135699 NM_001135700 NM_001135701 NM_001135702 NM_003406 NM_145690
RefSeq transcript (Entrez)NM_001135699 NM_001135700 NM_001135701 NM_001135702 NM_003406 NM_145690
RefSeq genomic (SRS)AC_000140 NC_000008 NC_018919 NT_008046 NW_001839136 NW_004078037
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NT_008046 NW_001839136 NW_004078037
Consensus coding sequences : CCDS (NCBI)YWHAZ
Cluster EST : UnigeneHs.492407 [ SRS ] Hs.492407 [ NCBI ]
CGAP (NCI)Hs.492407
Alternative Splicing : Fast-db (Paris)GSHG0029753
Alternative Splicing GalleryENSG00000164924
Gene ExpressionYWHAZ [ NCBI-GEO ]   YWHAZ [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP63104 (SRS) P63104 (Uniprot)
NextProtP63104
With graphics : InterProP63104
Splice isoforms : SwissVarP63104(Swissvar)
Domaine pattern : Prosite (SRS)1433_1 (PS00796)    1433_2 (PS00797)   
Domaine pattern : Prosite (Expaxy)1433_1 (PS00796)    1433_2 (PS00797)   
Domains : Interpro (SRS)14-3-3    14-3-3_CS    14-3-3_domain   
Domains : Interpro (EBI)14-3-3    14-3-3_CS    14-3-3_domain   
Related proteins : CluSTrP63104
Domain families : Pfam (SRS)14/03/03 (PF00244)   
Domain families : Pfam (Sanger)14/03/03 (PF00244)   
Domain families : Pfam (NCBI)pfam00244   
Domain families : Smart (EMBL)14_3_3 (SM00101)  
DMDM7534
Blocks (Seattle)P63104
PDB (SRS)1IB1    1QJA    1QJB    2C1J    2C1N    2O02    2WH0    3CU8    3NKX    3RDH    4FJ3   
PDB (PDBSum)1IB1    1QJA    1QJB    2C1J    2C1N    2O02    2WH0    3CU8    3NKX    3RDH    4FJ3   
PDB (IMB)1IB1    1QJA    1QJB    2C1J    2C1N    2O02    2WH0    3CU8    3NKX    3RDH    4FJ3   
PDB (RSDB)1IB1    1QJA    1QJB    2C1J    2C1N    2O02    2WH0    3CU8    3NKX    3RDH    4FJ3   
Human Protein AtlasENSG00000164924
HPRD03183
IPIIPI00021263   IPI00790689   IPI00793388   IPI00789337   IPI00979946   IPI00981067   IPI00981450   IPI00982101   IPI01011530   IPI01010931   IPI00983256   
Protein Interaction databases
DIP (DOE-UCLA)P63104
IntAct (EBI)P63104
FunCoupENSG00000164924
REACTOMEYWHAZ
Protein Interaction Database7534
BioGRIDYWHAZ
InParanoidP63104
Interologous Interaction database P63104
IntegromeDBYWHAZ
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)YWHAZ
SNP (GeneSNP Utah)YWHAZ
SNP : HGBaseYWHAZ
Genetic variants : HAPMAPYWHAZ
Somatic Mutations in Cancer : COSMICYWHAZ 
CONAN: Copy Number AnalysisYWHAZ 
Mutations and Diseases : HGMDYWHAZ
OMIM601288   
GENETests601288   
Disease Genetic AssociationYWHAZ
Huge Navigator YWHAZ [HugePedia]  YWHAZ [HugeCancerGEM]
Genomic VariantsYWHAZ  YWHAZ [DGVbeta]
ClinVarYWHAZ
snp3D : Map Gene to Disease7534
General knowledge
Homologs : HomoloGeneYWHAZ
Homology/Alignments : Family Browser (UCSC)YWHAZ
Phylogenetic Trees/Animal Genes : TreeFamYWHAZ
Chemical/Protein Interactions : CTD7534
Chemical/Pharm GKB GenePA37444
Clinical trialYWHAZ
Cancer Resource (Charite)ENSG00000164924
Ontology : AmiGOhistamine secretion by mast cell  protein binding  nucleoplasm  cytoplasm  mitochondrion  cytosol  protein targeting to mitochondrion  apoptotic process  signal transduction  blood coagulation  transcription factor binding  gene expression  postsynaptic density  cellular membrane organization  RNA metabolic process  mRNA metabolic process  protein kinase binding  protein domain specific binding  platelet activation  cytoplasmic vesicle membrane  cell leading edge  protein complex binding  melanosome  negative regulation of apoptotic process  protein complex  perinuclear region of cytoplasm  intrinsic apoptotic signaling pathway  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  
Ontology : EGO-EBIhistamine secretion by mast cell  protein binding  nucleoplasm  cytoplasm  mitochondrion  cytosol  protein targeting to mitochondrion  apoptotic process  signal transduction  blood coagulation  transcription factor binding  gene expression  postsynaptic density  cellular membrane organization  RNA metabolic process  mRNA metabolic process  protein kinase binding  protein domain specific binding  platelet activation  cytoplasmic vesicle membrane  cell leading edge  protein complex binding  melanosome  negative regulation of apoptotic process  protein complex  perinuclear region of cytoplasm  intrinsic apoptotic signaling pathway  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  
Pathways : KEGGCell cycle
Other databases
Probes
Litterature
PubMed301 Pubmed reference(s) in Entrez
PubGeneYWHAZ
iHOPYWHAZ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:49:25 CEST 2013
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