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YY1 (YY1 transcription factor)

Identity

Other namesDELTA
INO80S
NF-E1
UCRBP
YIN-YANG-1
HGNC (Hugo) YY1
LocusID (NCBI) 7528
Location 14q32.2
Location_base_pair Starts at 100705102 and ends at 100745371 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas)

Solid Tumors AmeloblastomID5945

External links

Nomenclature
HGNC (Hugo)YY1   12856
Cards
Entrez_Gene (NCBI)YY1  7528  YY1 transcription factor
GeneCards (Weizmann)YY1
Ensembl (Hinxton) [Gene_View]  chr14:100705102-100745371 [Contig_View]  YY1 [Vega]
AceView (NCBI)YY1
Genatlas (Paris)YY1
WikiGenes7528
SOURCE (Princeton)NM_003403
Genomic and cartography
GoldenPath (UCSC)YY1  -  14q32.2   chr14:100705102-100745371 +  14q32.2   [Description]    (hg19-Feb_2009)
EnsemblYY1 - 14q32.2 [CytoView]
Mapping of homologs : NCBIYY1 [Mapview]
OMIM600013   
Gene and transcription
Genbank (Entrez)AF147416 AK025731 AK026497 BC014138 BC020324
RefSeq transcript (Entrez)NM_003403
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838115 NW_004929393
Consensus coding sequences : CCDS (NCBI)YY1
Cluster EST : UnigeneHs.603118 [ NCBI ]
CGAP (NCI)Hs.603118
Alternative Splicing : Fast-db (Paris)GSHG0009112
Gene ExpressionYY1 [ NCBI-GEO ]     YY1 [ SEEK ]   YY1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25490 (Uniprot)
NextProtP25490  [Medical]
With graphics : InterProP25490
Splice isoforms : SwissVarP25490 (Swissvar)
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)TF_Yin_yang    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Related proteins : CluSTrP25490
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
DMDM Disease mutations7528
Blocks (Seattle)P25490
PDB (SRS)1UBD    1ZNM    4C5I   
PDB (PDBSum)1UBD    1ZNM    4C5I   
PDB (IMB)1UBD    1ZNM    4C5I   
PDB (RSDB)1UBD    1ZNM    4C5I   
Peptide AtlasP25490
HPRD02482
IPIIPI00014513   IPI01026056   IPI01025682   IPI01025781   
Protein Interaction databases
DIP (DOE-UCLA)P25490
IntAct (EBI)P25490
BioGRIDYY1
IntegromeDBYY1
STRING (EMBL)YY1
Ontologies - Pathways
QuickGOP25490
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  four-way junction DNA binding  double-strand break repair via homologous recombination  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  DNA binding  sequence-specific DNA binding transcription factor activity  transcription coactivator activity  transcription corepressor activity  RNA binding  protein binding  nucleus  transcription factor complex  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  RNA localization  cellular response to DNA damage stimulus  spermatogenesis  zinc ion binding  anterior/posterior pattern specification  response to UV-C  nuclear matrix  cell differentiation  Ino80 complex  PcG protein complex  cellular response to UV  response to prostaglandin F  transcription regulatory region DNA binding  camera-type eye morphogenesis  chromosome organization  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  four-way junction DNA binding  double-strand break repair via homologous recombination  RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription  DNA binding  sequence-specific DNA binding transcription factor activity  transcription coactivator activity  transcription corepressor activity  RNA binding  protein binding  nucleus  transcription factor complex  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  RNA localization  cellular response to DNA damage stimulus  spermatogenesis  zinc ion binding  anterior/posterior pattern specification  response to UV-C  nuclear matrix  cell differentiation  Ino80 complex  PcG protein complex  cellular response to UV  response to prostaglandin F  transcription regulatory region DNA binding  camera-type eye morphogenesis  chromosome organization  
Pathways : BIOCARTAThe PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails [Genes]   
Protein Interaction DatabaseYY1
Wikipedia pathwaysYY1
Gene fusion - rearrangments
Rearrangement : COSMICYY1 [14q32.2]  -  EWSR1 [22q12.2]
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)YY1
SNP (GeneSNP Utah)YY1
SNP : HGBaseYY1
Genetic variants : HAPMAPYY1
1000_GenomesYY1 
CONAN: Copy Number AnalysisYY1 
Somatic Mutations in Cancer : COSMICYY1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)14:100705102-100745371
Mutations and Diseases : HGMDYY1
OMIM600013   
MedgenYY1
GENETestsYY1
Disease Genetic AssociationYY1
Huge Navigator YY1 [HugePedia]  YY1 [HugeCancerGEM]
Genomic VariantsYY1  YY1 [DGVbeta]
Exome VariantYY1
dbVarYY1
ClinVarYY1
snp3D : Map Gene to Disease7528
General knowledge
Homologs : HomoloGeneYY1
Homology/Alignments : Family Browser (UCSC)YY1
Phylogenetic Trees/Animal Genes : TreeFamYY1
Chemical/Protein Interactions : CTD7528
Chemical/Pharm GKB GenePA37445
Clinical trialYY1
Other databases
Probes
Litterature
PubMed240 Pubmed reference(s) in Entrez
CoreMineYY1
GoPubMedYY1
iHOPYY1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 18:06:15 CET 2014

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