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YY2 (YY2 transcription factor)

Identity

Alias_symbol (synonym)ZNF631
Other alias
HGNC (Hugo) YY2
LocusID (NCBI) 404281
Atlas_Id 54062
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 21855987 and ends at 21858727 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MBTPS2 (Xp22.12) / YY2 (Xp22.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Prostate tumors: an overview
MBTPS2/YY2 (Xp22)


External links

Nomenclature
HGNC (Hugo)YY2   31684
Cards
Entrez_Gene (NCBI)YY2  404281  YY2 transcription factor
AliasesZNF631
GeneCards (Weizmann)YY2
Ensembl hg19 (Hinxton)ENSG00000230797 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000230797 [Gene_View]  ENSG00000230797 [Sequence]  chrX:21855987-21858727 [Contig_View]  YY2 [Vega]
ICGC DataPortalENSG00000230797
TCGA cBioPortalYY2
AceView (NCBI)YY2
Genatlas (Paris)YY2
WikiGenes404281
SOURCE (Princeton)YY2
Genetics Home Reference (NIH)YY2
Genomic and cartography
GoldenPath hg38 (UCSC)YY2  -     chrX:21855987-21858727 +  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)YY2  -     1q22   [Description]    (hg19-Feb_2009)
EnsemblYY2 - 1q22 [CytoView hg19]  YY2 - 1q22 [CytoView hg38]
Mapping of homologs : NCBIYY2 [Mapview hg19]  YY2 [Mapview hg38]
OMIM300570   
Gene and transcription
Genbank (Entrez)AK091850 AY567472 BC137215 BC137217 DA961884
RefSeq transcript (Entrez)NM_206923
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)YY2
Cluster EST : UnigeneHs.673601 [ NCBI ]
CGAP (NCI)Hs.673601
Alternative Splicing GalleryENSG00000230797
Gene ExpressionYY2 [ NCBI-GEO ]   YY2 [ EBI - ARRAY_EXPRESS ]   YY2 [ SEEK ]   YY2 [ MEM ]
Gene Expression Viewer (FireBrowse)YY2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)404281
GTEX Portal (Tissue expression)YY2
Human Protein AtlasENSG00000230797-YY2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15391   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15391  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15391
Splice isoforms : SwissVarO15391
PhosPhoSitePlusO15391
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)YY-1-like    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)YY2
DMDM Disease mutations404281
Blocks (Seattle)YY2
SuperfamilyO15391
Human Protein Atlas [tissue]ENSG00000230797-YY2 [tissue]
Peptide AtlasO15391
HPRD15684
IPIIPI00419912   
Protein Interaction databases
DIP (DOE-UCLA)O15391
IntAct (EBI)O15391
FunCoupENSG00000230797
BioGRIDYY2
STRING (EMBL)YY2
ZODIACYY2
Ontologies - Pathways
QuickGOO15391
Ontology : AmiGOnuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  proximal promoter sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II repressing transcription factor binding  transcriptional repressor activity, RNA polymerase II transcription factor binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA binding  nucleus  nucleus  transcription factor complex  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  PcG protein complex  sequence-specific DNA binding  sequence-specific DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBInuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  proximal promoter sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II repressing transcription factor binding  transcriptional repressor activity, RNA polymerase II transcription factor binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA binding  nucleus  nucleus  transcription factor complex  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  PcG protein complex  sequence-specific DNA binding  sequence-specific DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkYY2
Atlas of Cancer Signalling NetworkYY2
Wikipedia pathwaysYY2
Orthology - Evolution
OrthoDB404281
GeneTree (enSembl)ENSG00000230797
Phylogenetic Trees/Animal Genes : TreeFamYY2
HOVERGENO15391
HOGENOMO15391
Homologs : HomoloGeneYY2
Homology/Alignments : Family Browser (UCSC)YY2
Gene fusions - Rearrangements
Fusion : MitelmanMBTPS2/YY2 [Xp22.12/Xp22.12]  [t(X;X)(p22;p22)]  
Fusion : QuiverYY2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerYY2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)YY2
dbVarYY2
ClinVarYY2
1000_GenomesYY2 
Exome Variant ServerYY2
ExAC (Exome Aggregation Consortium)ENSG00000230797
GNOMAD BrowserENSG00000230797
Varsome BrowserYY2
Genetic variants : HAPMAP404281
Genomic Variants (DGV)YY2 [DGVbeta]
DECIPHERYY2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisYY2 
Mutations
ICGC Data PortalYY2 
TCGA Data PortalYY2 
Broad Tumor PortalYY2
OASIS PortalYY2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICYY2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDYY2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch YY2
DgiDB (Drug Gene Interaction Database)YY2
DoCM (Curated mutations)YY2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)YY2 (select a term)
intoGenYY2
Cancer3DYY2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300570   
Orphanet
DisGeNETYY2
MedgenYY2
Genetic Testing Registry YY2
NextProtO15391 [Medical]
TSGene404281
GENETestsYY2
Target ValidationYY2
Huge Navigator YY2 [HugePedia]
snp3D : Map Gene to Disease404281
BioCentury BCIQYY2
ClinGenYY2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD404281
Chemical/Pharm GKB GenePA134976542
Clinical trialYY2
Miscellaneous
canSAR (ICR)YY2 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineYY2
EVEXYY2
GoPubMedYY2
iHOPYY2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Aug 16 11:42:14 CEST 2018

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