Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZBTB1 (zinc finger and BTB domain containing 1)

Identity

Alias_symbol (synonym)KIAA0997
ZNF909
Other alias
HGNC (Hugo) ZBTB1
LocusID (NCBI) 22890
Atlas_Id 53927
Location 14q23.3  [Link to chromosome band 14q23]
Location_base_pair Starts at 64971292 and ends at 64991669 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BAP1 (3p21.1) / ZBTB1 (14q23.3)ZBTB1 (14q23.3) / MTHFD1 (14q23.3)ZBTB1 14q23.3 / MTHFD1 14q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZBTB1   20259
Cards
Entrez_Gene (NCBI)ZBTB1  22890  zinc finger and BTB domain containing 1
AliasesZNF909
GeneCards (Weizmann)ZBTB1
Ensembl hg19 (Hinxton)ENSG00000126804 [Gene_View]  chr14:64971292-64991669 [Contig_View]  ZBTB1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000126804 [Gene_View]  chr14:64971292-64991669 [Contig_View]  ZBTB1 [Vega]
ICGC DataPortalENSG00000126804
TCGA cBioPortalZBTB1
AceView (NCBI)ZBTB1
Genatlas (Paris)ZBTB1
WikiGenes22890
SOURCE (Princeton)ZBTB1
Genetics Home Reference (NIH)ZBTB1
Genomic and cartography
GoldenPath hg19 (UCSC)ZBTB1  -     chr14:64971292-64991669 +  14q23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZBTB1  -     14q23.3   [Description]    (hg38-Dec_2013)
EnsemblZBTB1 - 14q23.3 [CytoView hg19]  ZBTB1 - 14q23.3 [CytoView hg38]
Mapping of homologs : NCBIZBTB1 [Mapview hg19]  ZBTB1 [Mapview hg38]
OMIM616578   
Gene and transcription
Genbank (Entrez)AB023214 AK291743 AW965994 AY598321 BC050719
RefSeq transcript (Entrez)NM_001123329 NM_014950
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)ZBTB1
Cluster EST : UnigeneHs.605143 [ NCBI ]
CGAP (NCI)Hs.605143
Alternative Splicing GalleryENSG00000126804
Gene ExpressionZBTB1 [ NCBI-GEO ]   ZBTB1 [ EBI - ARRAY_EXPRESS ]   ZBTB1 [ SEEK ]   ZBTB1 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22890
GTEX Portal (Tissue expression)ZBTB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2K1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2K1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2K1
Splice isoforms : SwissVarQ9Y2K1
PhosPhoSitePlusQ9Y2K1
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB1
DMDM Disease mutations22890
Blocks (Seattle)ZBTB1
SuperfamilyQ9Y2K1
Human Protein AtlasENSG00000126804
Peptide AtlasQ9Y2K1
HPRD15688
IPIIPI00007273   IPI00873559   IPI01025278   IPI01026102   IPI01025807   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2K1
IntAct (EBI)Q9Y2K1
FunCoupENSG00000126804
BioGRIDZBTB1
STRING (EMBL)ZBTB1
ZODIACZBTB1
Ontologies - Pathways
QuickGOQ9Y2K1
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  positive regulation of T cell mediated immunity  DNA binding  protein binding  nucleus  nucleoplasm  DNA repair  chromatin remodeling  cellular response to DNA damage stimulus  nuclear body  translesion synthesis  B cell differentiation  positive regulation of natural killer cell differentiation  T cell differentiation in thymus  cellular response to UV  mRNA transcription from RNA polymerase II promoter  protein homodimerization activity  innate immune response  positive regulation of T cell differentiation  metal ion binding  protein heterodimerization activity  thymus development  protein homooligomerization  K63-linked polyubiquitin binding  positive regulation of pro-T cell differentiation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  positive regulation of T cell mediated immunity  DNA binding  protein binding  nucleus  nucleoplasm  DNA repair  chromatin remodeling  cellular response to DNA damage stimulus  nuclear body  translesion synthesis  B cell differentiation  positive regulation of natural killer cell differentiation  T cell differentiation in thymus  cellular response to UV  mRNA transcription from RNA polymerase II promoter  protein homodimerization activity  innate immune response  positive regulation of T cell differentiation  metal ion binding  protein heterodimerization activity  thymus development  protein homooligomerization  K63-linked polyubiquitin binding  positive regulation of pro-T cell differentiation  
NDEx NetworkZBTB1
Atlas of Cancer Signalling NetworkZBTB1
Wikipedia pathwaysZBTB1
Orthology - Evolution
OrthoDB22890
GeneTree (enSembl)ENSG00000126804
Phylogenetic Trees/Animal Genes : TreeFamZBTB1
HOVERGENQ9Y2K1
HOGENOMQ9Y2K1
Homologs : HomoloGeneZBTB1
Homology/Alignments : Family Browser (UCSC)ZBTB1
Gene fusions - Rearrangements
Fusion : MitelmanZBTB1/MTHFD1 [14q23.3/14q23.3]  
Fusion: TCGAZBTB1 14q23.3 MTHFD1 14q23.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB1
dbVarZBTB1
ClinVarZBTB1
1000_GenomesZBTB1 
Exome Variant ServerZBTB1
ExAC (Exome Aggregation Consortium)ZBTB1 (select the gene name)
Genetic variants : HAPMAP22890
Genomic Variants (DGV)ZBTB1 [DGVbeta]
DECIPHER (Syndromes)14:64971292-64991669  ENSG00000126804
CONAN: Copy Number AnalysisZBTB1 
Mutations
ICGC Data PortalZBTB1 
TCGA Data PortalZBTB1 
Broad Tumor PortalZBTB1
OASIS PortalZBTB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZBTB1
DgiDB (Drug Gene Interaction Database)ZBTB1
DoCM (Curated mutations)ZBTB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB1 (select a term)
intoGenZBTB1
Cancer3DZBTB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616578   
Orphanet
MedgenZBTB1
Genetic Testing Registry ZBTB1
NextProtQ9Y2K1 [Medical]
TSGene22890
GENETestsZBTB1
Huge Navigator ZBTB1 [HugePedia]
snp3D : Map Gene to Disease22890
BioCentury BCIQZBTB1
ClinGenZBTB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22890
Chemical/Pharm GKB GenePA128395769
Clinical trialZBTB1
Miscellaneous
canSAR (ICR)ZBTB1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB1
EVEXZBTB1
GoPubMedZBTB1
iHOPZBTB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:34:36 CET 2017

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