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ZBTB17 (zinc finger and BTB domain containing 17)

Identity

Alias (NCBI)MIZ-1
ZNF151
ZNF60
pHZ-67
HGNC (Hugo) ZBTB17
HGNC Alias symbMIZ1
pHZ-67
HGNC Previous nameZNF151
 ZNF60
HGNC Previous namezinc finger protein 151 (pHZ-67)
 zinc finger protein 60
LocusID (NCBI) 7709
Atlas_Id 42872
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 15941869 and ends at 15976132 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RPAIN (17p13.2) / ZBTB17 (1p36.13)ZBTB17 (1p36.13) / AP2A1 (19q13.33)ZBTB17 (1p36.13) / FAM131C (1p36.13)
ZBTB17 1p36.13 / FAM131C 1p36.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZBTB17   12936
Cards
Entrez_Gene (NCBI)ZBTB17    zinc finger and BTB domain containing 17
AliasesMIZ-1; ZNF151; ZNF60; pHZ-67
GeneCards (Weizmann)ZBTB17
Ensembl hg19 (Hinxton)ENSG00000116809 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116809 [Gene_View]  ENSG00000116809 [Sequence]  chr1:15941869-15976132 [Contig_View]  ZBTB17 [Vega]
ICGC DataPortalENSG00000116809
TCGA cBioPortalZBTB17
AceView (NCBI)ZBTB17
Genatlas (Paris)ZBTB17
SOURCE (Princeton)ZBTB17
Genetics Home Reference (NIH)ZBTB17
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB17  -     chr1:15941869-15976132 -  1p36.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB17  -     1p36.13   [Description]    (hg19-Feb_2009)
GoldenPathZBTB17 - 1p36.13 [CytoView hg19]  ZBTB17 - 1p36.13 [CytoView hg38]
ImmunoBaseENSG00000116809
Genome Data Viewer NCBIZBTB17 [Mapview hg19]  
OMIM604084   
Gene and transcription
Genbank (Entrez)AK223618 AK226168 AK294796 AK299820 AK301896
RefSeq transcript (Entrez)NM_001242884 NM_001287603 NM_001287604 NM_001324137 NM_001324138 NM_003443
Consensus coding sequences : CCDS (NCBI)ZBTB17
Gene ExpressionZBTB17 [ NCBI-GEO ]   ZBTB17 [ EBI - ARRAY_EXPRESS ]   ZBTB17 [ SEEK ]   ZBTB17 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB17 [ Firebrowse - Broad ]
GenevisibleExpression of ZBTB17 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7709
GTEX Portal (Tissue expression)ZBTB17
Human Protein AtlasENSG00000116809-ZBTB17 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13105   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13105  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13105
PhosPhoSitePlusQ13105
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)BTB (PF00651)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00651    pfam00096   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB17
PDB (RSDB)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
PDB Europe2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
PDB (PDBSum)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
PDB (IMB)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
Structural Biology KnowledgeBase2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
SCOP (Structural Classification of Proteins)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
CATH (Classification of proteins structures)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
SuperfamilyQ13105
AlphaFold pdb e-kbQ13105   
Human Protein Atlas [tissue]ENSG00000116809-ZBTB17 [tissue]
HPRD04968
Protein Interaction databases
DIP (DOE-UCLA)Q13105
IntAct (EBI)Q13105
BioGRIDZBTB17
STRING (EMBL)ZBTB17
ZODIACZBTB17
Ontologies - Pathways
QuickGOQ13105
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  core promoter sequence-specific DNA binding  transcription coactivator binding  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  gastrulation with mouth forming second  DNA-binding transcription factor activity  protein binding  nucleoplasm  nucleoplasm  regulation of transcription by RNA polymerase II  ectoderm development  negative regulation of cell population proliferation  protein-containing complex  protein-DNA complex  IRE1-mediated unfolded protein response  negative regulation of cell cycle  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  regulation of cell cycle  DNA-binding transcription factor binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  core promoter sequence-specific DNA binding  transcription coactivator binding  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  gastrulation with mouth forming second  DNA-binding transcription factor activity  protein binding  nucleoplasm  nucleoplasm  regulation of transcription by RNA polymerase II  ectoderm development  negative regulation of cell population proliferation  protein-containing complex  protein-DNA complex  IRE1-mediated unfolded protein response  negative regulation of cell cycle  positive regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  regulation of cell cycle  DNA-binding transcription factor binding  
Pathways : KEGGCell cycle    Transcriptional misregulation in cancer   
NDEx NetworkZBTB17
Atlas of Cancer Signalling NetworkZBTB17
Wikipedia pathwaysZBTB17
Orthology - Evolution
OrthoDB7709
GeneTree (enSembl)ENSG00000116809
Phylogenetic Trees/Animal Genes : TreeFamZBTB17
Homologs : HomoloGeneZBTB17
Homology/Alignments : Family Browser (UCSC)ZBTB17
Gene fusions - Rearrangements
Fusion : MitelmanZBTB17/FAM131C [1p36.13/1p36.13]  
Fusion : QuiverZBTB17
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB17 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB17
dbVarZBTB17
ClinVarZBTB17
MonarchZBTB17
1000_GenomesZBTB17 
Exome Variant ServerZBTB17
GNOMAD BrowserENSG00000116809
Varsome BrowserZBTB17
ACMGZBTB17 variants
VarityQ13105
Genomic Variants (DGV)ZBTB17 [DGVbeta]
DECIPHERZBTB17 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB17 
Mutations
ICGC Data PortalZBTB17 
TCGA Data PortalZBTB17 
Broad Tumor PortalZBTB17
OASIS PortalZBTB17 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB17  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZBTB17
Mutations and Diseases : HGMDZBTB17
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZBTB17
DgiDB (Drug Gene Interaction Database)ZBTB17
DoCM (Curated mutations)ZBTB17
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB17
Cancer3DZBTB17
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604084   
Orphanet
DisGeNETZBTB17
MedgenZBTB17
Genetic Testing Registry ZBTB17
NextProtQ13105 [Medical]
GENETestsZBTB17
Target ValidationZBTB17
Huge Navigator ZBTB17 [HugePedia]
ClinGenZBTB17
Clinical trials, drugs, therapy
MyCancerGenomeZBTB17
Protein Interactions : CTDZBTB17
Pharm GKB GenePA37522
PharosQ13105
Clinical trialZBTB17
Miscellaneous
canSAR (ICR)ZBTB17
HarmonizomeZBTB17
DataMed IndexZBTB17
Probes
Litterature
PubMed89 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZBTB17
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:38:45 CEST 2021

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