Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZBTB17 (zinc finger and BTB domain containing 17)

Identity

Alias_namesZNF151
ZNF60
zinc finger protein 151 (pHZ-67)
zinc finger protein 60
Alias_symbol (synonym)MIZ1
pHZ-67
Other aliasMIZ-1
HGNC (Hugo) ZBTB17
LocusID (NCBI) 7709
Atlas_Id 42872
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 15941869 and ends at 15976132 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RPAIN (17p13.2) / ZBTB17 (1p36.13)ZBTB17 (1p36.13) / AP2A1 (19q13.33)ZBTB17 (1p36.13) / FAM131C (1p36.13)
ZBTB17 1p36.13 / FAM131C 1p36.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZBTB17   12936
Cards
Entrez_Gene (NCBI)ZBTB17  7709  zinc finger and BTB domain containing 17
AliasesMIZ-1; ZNF151; ZNF60; pHZ-67
GeneCards (Weizmann)ZBTB17
Ensembl hg19 (Hinxton)ENSG00000116809 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116809 [Gene_View]  chr1:15941869-15976132 [Contig_View]  ZBTB17 [Vega]
ICGC DataPortalENSG00000116809
TCGA cBioPortalZBTB17
AceView (NCBI)ZBTB17
Genatlas (Paris)ZBTB17
WikiGenes7709
SOURCE (Princeton)ZBTB17
Genetics Home Reference (NIH)ZBTB17
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB17  -     chr1:15941869-15976132 -  1p36.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB17  -     1p36.13   [Description]    (hg19-Feb_2009)
EnsemblZBTB17 - 1p36.13 [CytoView hg19]  ZBTB17 - 1p36.13 [CytoView hg38]
Mapping of homologs : NCBIZBTB17 [Mapview hg19]  ZBTB17 [Mapview hg38]
OMIM604084   
Gene and transcription
Genbank (Entrez)AK223618 AK226168 AK294796 AK299820 AK301896
RefSeq transcript (Entrez)NM_001242884 NM_001287603 NM_001287604 NM_001324137 NM_001324138 NM_003443
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBTB17
Cluster EST : UnigeneHs.433764 [ NCBI ]
CGAP (NCI)Hs.433764
Alternative Splicing GalleryENSG00000116809
Gene ExpressionZBTB17 [ NCBI-GEO ]   ZBTB17 [ EBI - ARRAY_EXPRESS ]   ZBTB17 [ SEEK ]   ZBTB17 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB17 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7709
GTEX Portal (Tissue expression)ZBTB17
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13105   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13105  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13105
Splice isoforms : SwissVarQ13105
PhosPhoSitePlusQ13105
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)BTB (PF00651)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00651    pfam00096   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB17
DMDM Disease mutations7709
Blocks (Seattle)ZBTB17
PDB (SRS)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
PDB (PDBSum)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
PDB (IMB)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
PDB (RSDB)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
Structural Biology KnowledgeBase2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
SCOP (Structural Classification of Proteins)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
CATH (Classification of proteins structures)2LVR    2LVT    2LVU    2M0D    2M0E    2M0F    2N25    2N26    2Q81    3M52    4U2M    4U2N    5ION   
SuperfamilyQ13105
Human Protein AtlasENSG00000116809
Peptide AtlasQ13105
HPRD04968
IPIIPI00011834   IPI00556634   IPI00909321   IPI01009418   IPI00909476   IPI00552525   
Protein Interaction databases
DIP (DOE-UCLA)Q13105
IntAct (EBI)Q13105
FunCoupENSG00000116809
BioGRIDZBTB17
STRING (EMBL)ZBTB17
ZODIACZBTB17
Ontologies - Pathways
QuickGOQ13105
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  core promoter binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription coactivator binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  gastrulation with mouth forming second  transcription factor activity, sequence-specific DNA binding  protein binding  nucleoplasm  transcription from RNA polymerase II promoter  ectoderm development  transcription factor binding  negative regulation of cell proliferation  protein-DNA complex  IRE1-mediated unfolded protein response  protein complex  negative regulation of cell cycle  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  positive regulation of cell cycle arrest  regulation of mitophagy  positive regulation of protein targeting to mitochondrion  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  core promoter binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription coactivator binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  gastrulation with mouth forming second  transcription factor activity, sequence-specific DNA binding  protein binding  nucleoplasm  transcription from RNA polymerase II promoter  ectoderm development  transcription factor binding  negative regulation of cell proliferation  protein-DNA complex  IRE1-mediated unfolded protein response  protein complex  negative regulation of cell cycle  positive regulation of transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  positive regulation of cell cycle arrest  regulation of mitophagy  positive regulation of protein targeting to mitochondrion  
Pathways : KEGGCell cycle    Transcriptional misregulation in cancer   
NDEx NetworkZBTB17
Atlas of Cancer Signalling NetworkZBTB17
Wikipedia pathwaysZBTB17
Orthology - Evolution
OrthoDB7709
GeneTree (enSembl)ENSG00000116809
Phylogenetic Trees/Animal Genes : TreeFamZBTB17
HOVERGENQ13105
HOGENOMQ13105
Homologs : HomoloGeneZBTB17
Homology/Alignments : Family Browser (UCSC)ZBTB17
Gene fusions - Rearrangements
Fusion : MitelmanZBTB17/FAM131C [1p36.13/1p36.13]  
Fusion: TCGAZBTB17 1p36.13 FAM131C 1p36.13 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB17 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB17
dbVarZBTB17
ClinVarZBTB17
1000_GenomesZBTB17 
Exome Variant ServerZBTB17
ExAC (Exome Aggregation Consortium)ZBTB17 (select the gene name)
Genetic variants : HAPMAP7709
Genomic Variants (DGV)ZBTB17 [DGVbeta]
DECIPHERZBTB17 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB17 
Mutations
ICGC Data PortalZBTB17 
TCGA Data PortalZBTB17 
Broad Tumor PortalZBTB17
OASIS PortalZBTB17 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB17  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB17
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch ZBTB17
DgiDB (Drug Gene Interaction Database)ZBTB17
DoCM (Curated mutations)ZBTB17 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB17 (select a term)
intoGenZBTB17
Cancer3DZBTB17(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604084   
Orphanet
MedgenZBTB17
Genetic Testing Registry ZBTB17
NextProtQ13105 [Medical]
TSGene7709
GENETestsZBTB17
Target ValidationZBTB17
Huge Navigator ZBTB17 [HugePedia]
snp3D : Map Gene to Disease7709
BioCentury BCIQZBTB17
ClinGenZBTB17
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7709
Chemical/Pharm GKB GenePA37522
Clinical trialZBTB17
Miscellaneous
canSAR (ICR)ZBTB17 (select the gene name)
Probes
Litterature
PubMed70 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB17
EVEXZBTB17
GoPubMedZBTB17
iHOPZBTB17
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:03:16 CEST 2017

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