Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZBTB18 (zinc finger and BTB domain containing 18)

Identity

Alias_namesZNF238
zinc finger protein 238
Alias_symbol (synonym)C2H2-171
TAZ-1
RP58
Other aliasMRD22
HGNC (Hugo) ZBTB18
LocusID (NCBI) 10472
Atlas_Id 51384
Location 1q44  [Link to chromosome band 1q44]
Location_base_pair Starts at 244051259 and ends at 244057478 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLU (8p21.1) / ZBTB18 (1q44)N4BP2L1 (13q13.1) / ZBTB18 (1q44)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZBTB18   13030
Cards
Entrez_Gene (NCBI)ZBTB18  10472  zinc finger and BTB domain containing 18
AliasesC2H2-171; MRD22; RP58; TAZ-1; 
ZNF238
GeneCards (Weizmann)ZBTB18
Ensembl hg19 (Hinxton)ENSG00000179456 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179456 [Gene_View]  ENSG00000179456 [Sequence]  chr1:244051259-244057478 [Contig_View]  ZBTB18 [Vega]
ICGC DataPortalENSG00000179456
TCGA cBioPortalZBTB18
AceView (NCBI)ZBTB18
Genatlas (Paris)ZBTB18
WikiGenes10472
SOURCE (Princeton)ZBTB18
Genetics Home Reference (NIH)ZBTB18
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB18  -     chr1:244051259-244057478 +  1q44   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB18  -     1q44   [Description]    (hg19-Feb_2009)
GoldenPathZBTB18 - 1q44 [CytoView hg19]  ZBTB18 - 1q44 [CytoView hg38]
ImmunoBaseENSG00000179456
Mapping of homologs : NCBIZBTB18 [Mapview hg19]  ZBTB18 [Mapview hg38]
OMIM608433   612337   
Gene and transcription
Genbank (Entrez)AJ001388 AK291408 AK293892 AL050055 BC036677
RefSeq transcript (Entrez)NM_001278196 NM_006352 NM_205768
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBTB18
Cluster EST : UnigeneHs.69997 [ NCBI ]
CGAP (NCI)Hs.69997
Alternative Splicing GalleryENSG00000179456
Gene ExpressionZBTB18 [ NCBI-GEO ]   ZBTB18 [ EBI - ARRAY_EXPRESS ]   ZBTB18 [ SEEK ]   ZBTB18 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10472
GTEX Portal (Tissue expression)ZBTB18
Human Protein AtlasENSG00000179456-ZBTB18 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99592   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99592  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99592
Splice isoforms : SwissVarQ99592
PhosPhoSitePlusQ99592
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB18
DMDM Disease mutations10472
Blocks (Seattle)ZBTB18
SuperfamilyQ99592
Human Protein Atlas [tissue]ENSG00000179456-ZBTB18 [tissue]
Peptide AtlasQ99592
HPRD12231
IPIIPI00007360   IPI00409637   IPI01014187   
Protein Interaction databases
DIP (DOE-UCLA)Q99592
IntAct (EBI)Q99592
FunCoupENSG00000179456
BioGRIDZBTB18
STRING (EMBL)ZBTB18
ZODIACZBTB18
Ontologies - Pathways
QuickGOQ99592
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  nuclear chromosome  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  transcription coactivator activity  protein binding  nucleus  nucleus  nucleus  cellular response to DNA damage stimulus  skeletal muscle tissue development  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  nuclear chromosome  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  transcription coactivator activity  protein binding  nucleus  nucleus  nucleus  cellular response to DNA damage stimulus  skeletal muscle tissue development  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZBTB18
Atlas of Cancer Signalling NetworkZBTB18
Wikipedia pathwaysZBTB18
Orthology - Evolution
OrthoDB10472
GeneTree (enSembl)ENSG00000179456
Phylogenetic Trees/Animal Genes : TreeFamZBTB18
HOGENOMQ99592
Homologs : HomoloGeneZBTB18
Homology/Alignments : Family Browser (UCSC)ZBTB18
Gene fusions - Rearrangements
Fusion : QuiverZBTB18
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB18
dbVarZBTB18
ClinVarZBTB18
1000_GenomesZBTB18 
Exome Variant ServerZBTB18
ExAC (Exome Aggregation Consortium)ENSG00000179456
GNOMAD BrowserENSG00000179456
Varsome BrowserZBTB18
Genetic variants : HAPMAP10472
Genomic Variants (DGV)ZBTB18 [DGVbeta]
DECIPHERZBTB18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB18 
Mutations
ICGC Data PortalZBTB18 
TCGA Data PortalZBTB18 
Broad Tumor PortalZBTB18
OASIS PortalZBTB18 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDZBTB18
BioMutasearch ZBTB18
DgiDB (Drug Gene Interaction Database)ZBTB18
DoCM (Curated mutations)ZBTB18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB18 (select a term)
intoGenZBTB18
Cancer3DZBTB18(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608433    612337   
Orphanet10418   
DisGeNETZBTB18
MedgenZBTB18
Genetic Testing Registry ZBTB18
NextProtQ99592 [Medical]
TSGene10472
GENETestsZBTB18
Target ValidationZBTB18
Huge Navigator ZBTB18 [HugePedia]
snp3D : Map Gene to Disease10472
BioCentury BCIQZBTB18
ClinGenZBTB18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10472
Chemical/Pharm GKB GenePA37608
Clinical trialZBTB18
Miscellaneous
canSAR (ICR)ZBTB18 (select the gene name)
DataMed IndexZBTB18
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB18
EVEXZBTB18
GoPubMedZBTB18
iHOPZBTB18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 26 18:35:43 CEST 2019

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