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ZBTB18 (zinc finger and BTB domain containing 18)

Identity

Alias (NCBI)C2H2-171
MRD22
RP58
TAZ-1
ZNF238
HGNC (Hugo) ZBTB18
HGNC Alias symbC2H2-171
TAZ-1
RP58
HGNC Previous nameZNF238
HGNC Previous namezinc finger protein 238
LocusID (NCBI) 10472
Atlas_Id 51384
Location 1q44  [Link to chromosome band 1q44]
Location_base_pair Starts at 244051259 and ends at 244057478 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLU (8p21.1) / ZBTB18 (1q44)N4BP2L1 (13q13.1) / ZBTB18 (1q44)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZBTB18   13030
Cards
Entrez_Gene (NCBI)ZBTB18    zinc finger and BTB domain containing 18
AliasesC2H2-171; MRD22; RP58; TAZ-1; 
ZNF238
GeneCards (Weizmann)ZBTB18
Ensembl hg19 (Hinxton)ENSG00000179456 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179456 [Gene_View]  ENSG00000179456 [Sequence]  chr1:244051259-244057478 [Contig_View]  ZBTB18 [Vega]
ICGC DataPortalENSG00000179456
TCGA cBioPortalZBTB18
AceView (NCBI)ZBTB18
Genatlas (Paris)ZBTB18
SOURCE (Princeton)ZBTB18
Genetics Home Reference (NIH)ZBTB18
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB18  -     chr1:244051259-244057478 +  1q44   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB18  -     1q44   [Description]    (hg19-Feb_2009)
GoldenPathZBTB18 - 1q44 [CytoView hg19]  ZBTB18 - 1q44 [CytoView hg38]
ImmunoBaseENSG00000179456
Genome Data Viewer NCBIZBTB18 [Mapview hg19]  
OMIM608433   612337   
Gene and transcription
Genbank (Entrez)AJ001388 AK291408 AK293892 AL050055 BC036677
RefSeq transcript (Entrez)NM_001278196 NM_006352 NM_205768
Consensus coding sequences : CCDS (NCBI)ZBTB18
Gene ExpressionZBTB18 [ NCBI-GEO ]   ZBTB18 [ EBI - ARRAY_EXPRESS ]   ZBTB18 [ SEEK ]   ZBTB18 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB18 [ Firebrowse - Broad ]
GenevisibleExpression of ZBTB18 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10472
GTEX Portal (Tissue expression)ZBTB18
Human Protein AtlasENSG00000179456-ZBTB18 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99592   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99592  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99592
PhosPhoSitePlusQ99592
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)BTB (PF00651)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00651    pfam00096   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB18
SuperfamilyQ99592
AlphaFold pdb e-kbQ99592   
Human Protein Atlas [tissue]ENSG00000179456-ZBTB18 [tissue]
HPRD12231
Protein Interaction databases
DIP (DOE-UCLA)Q99592
IntAct (EBI)Q99592
BioGRIDZBTB18
STRING (EMBL)ZBTB18
ZODIACZBTB18
Ontologies - Pathways
QuickGOQ99592
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  heterochromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  nucleus  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  skeletal muscle tissue development  nuclear speck  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  metal ion binding  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  heterochromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  nucleus  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  skeletal muscle tissue development  nuclear speck  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  metal ion binding  sequence-specific double-stranded DNA binding  
NDEx NetworkZBTB18
Atlas of Cancer Signalling NetworkZBTB18
Wikipedia pathwaysZBTB18
Orthology - Evolution
OrthoDB10472
GeneTree (enSembl)ENSG00000179456
Phylogenetic Trees/Animal Genes : TreeFamZBTB18
Homologs : HomoloGeneZBTB18
Homology/Alignments : Family Browser (UCSC)ZBTB18
Gene fusions - Rearrangements
Fusion : QuiverZBTB18
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB18
dbVarZBTB18
ClinVarZBTB18
MonarchZBTB18
1000_GenomesZBTB18 
Exome Variant ServerZBTB18
GNOMAD BrowserENSG00000179456
Varsome BrowserZBTB18
ACMGZBTB18 variants
VarityQ99592
Genomic Variants (DGV)ZBTB18 [DGVbeta]
DECIPHERZBTB18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB18 
Mutations
ICGC Data PortalZBTB18 
TCGA Data PortalZBTB18 
Broad Tumor PortalZBTB18
OASIS PortalZBTB18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB18  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZBTB18
Mutations and Diseases : HGMDZBTB18
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZBTB18
DgiDB (Drug Gene Interaction Database)ZBTB18
DoCM (Curated mutations)ZBTB18
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB18
Cancer3DZBTB18
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608433    612337   
Orphanet10418   
DisGeNETZBTB18
MedgenZBTB18
Genetic Testing Registry ZBTB18
NextProtQ99592 [Medical]
GENETestsZBTB18
Target ValidationZBTB18
Huge Navigator ZBTB18 [HugePedia]
ClinGenZBTB18
Clinical trials, drugs, therapy
MyCancerGenomeZBTB18
Protein Interactions : CTDZBTB18
Pharm GKB GenePA37608
PharosQ99592
Clinical trialZBTB18
Miscellaneous
canSAR (ICR)ZBTB18
HarmonizomeZBTB18
DataMed IndexZBTB18
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZBTB18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:38:46 CEST 2021

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