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ZBTB24 (zinc finger and BTB domain containing 24)

Identity

Other aliasBIF1
ICF2
PATZ2
ZNF450
HGNC (Hugo) ZBTB24
LocusID (NCBI) 9841
Atlas_Id 56859
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 109462516 and ends at 109483237 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SYN3 (22q12.3) / ZBTB24 (6q21)ZBTB24 (6q21) / CMAHP (6p22.3)ZBTB24 (6q21) / SCML4 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p22;q21) ZBTB24/CMAHP


External links

Nomenclature
HGNC (Hugo)ZBTB24   21143
LRG (Locus Reference Genomic)LRG_326
Cards
Entrez_Gene (NCBI)ZBTB24  9841  zinc finger and BTB domain containing 24
AliasesBIF1; ICF2; PATZ2; ZNF450
GeneCards (Weizmann)ZBTB24
Ensembl hg19 (Hinxton)ENSG00000112365 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112365 [Gene_View]  ENSG00000112365 [Sequence]  chr6:109462516-109483237 [Contig_View]  ZBTB24 [Vega]
ICGC DataPortalENSG00000112365
TCGA cBioPortalZBTB24
AceView (NCBI)ZBTB24
Genatlas (Paris)ZBTB24
WikiGenes9841
SOURCE (Princeton)ZBTB24
Genetics Home Reference (NIH)ZBTB24
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB24  -     chr6:109462516-109483237 -  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB24  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblZBTB24 - 6q21 [CytoView hg19]  ZBTB24 - 6q21 [CytoView hg38]
Mapping of homologs : NCBIZBTB24 [Mapview hg19]  ZBTB24 [Mapview hg38]
OMIM614064   614069   
Gene and transcription
Genbank (Entrez)AB007901 AK309697 BC036731 BC117374 BC117376
RefSeq transcript (Entrez)NM_001164313 NM_014797
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBTB24
Cluster EST : UnigeneHs.409876 [ NCBI ]
CGAP (NCI)Hs.409876
Alternative Splicing GalleryENSG00000112365
Gene ExpressionZBTB24 [ NCBI-GEO ]   ZBTB24 [ EBI - ARRAY_EXPRESS ]   ZBTB24 [ SEEK ]   ZBTB24 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB24 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9841
GTEX Portal (Tissue expression)ZBTB24
Human Protein AtlasENSG00000112365-ZBTB24 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43167   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43167  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43167
Splice isoforms : SwissVarO43167
PhosPhoSitePlusO43167
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB24
DMDM Disease mutations9841
Blocks (Seattle)ZBTB24
SuperfamilyO43167
Human Protein Atlas [tissue]ENSG00000112365-ZBTB24 [tissue]
Peptide AtlasO43167
IPIIPI00011180   IPI00656048   
Protein Interaction databases
DIP (DOE-UCLA)O43167
IntAct (EBI)O43167
FunCoupENSG00000112365
BioGRIDZBTB24
STRING (EMBL)ZBTB24
ZODIACZBTB24
Ontologies - Pathways
QuickGOO43167
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  hematopoietic progenitor cell differentiation  DNA-binding transcription factor activity  protein binding  nucleoplasm  transcription regulatory region DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  hematopoietic progenitor cell differentiation  DNA-binding transcription factor activity  protein binding  nucleoplasm  transcription regulatory region DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZBTB24
Atlas of Cancer Signalling NetworkZBTB24
Wikipedia pathwaysZBTB24
Orthology - Evolution
OrthoDB9841
GeneTree (enSembl)ENSG00000112365
Phylogenetic Trees/Animal Genes : TreeFamZBTB24
HOVERGENO43167
HOGENOMO43167
Homologs : HomoloGeneZBTB24
Homology/Alignments : Family Browser (UCSC)ZBTB24
Gene fusions - Rearrangements
Fusion : QuiverZBTB24
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB24 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB24
dbVarZBTB24
ClinVarZBTB24
1000_GenomesZBTB24 
Exome Variant ServerZBTB24
ExAC (Exome Aggregation Consortium)ENSG00000112365
GNOMAD BrowserENSG00000112365
Varsome BrowserZBTB24
Genetic variants : HAPMAP9841
Genomic Variants (DGV)ZBTB24 [DGVbeta]
DECIPHERZBTB24 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB24 
Mutations
ICGC Data PortalZBTB24 
TCGA Data PortalZBTB24 
Broad Tumor PortalZBTB24
OASIS PortalZBTB24 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB24  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB24
BioMutasearch ZBTB24
DgiDB (Drug Gene Interaction Database)ZBTB24
DoCM (Curated mutations)ZBTB24 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB24 (select a term)
intoGenZBTB24
Cancer3DZBTB24(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614064    614069   
Orphanet
DisGeNETZBTB24
MedgenZBTB24
Genetic Testing Registry ZBTB24
NextProtO43167 [Medical]
TSGene9841
GENETestsZBTB24
Target ValidationZBTB24
Huge Navigator ZBTB24 [HugePedia]
snp3D : Map Gene to Disease9841
BioCentury BCIQZBTB24
ClinGenZBTB24
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9841
Chemical/Pharm GKB GenePA134904966
Clinical trialZBTB24
Miscellaneous
canSAR (ICR)ZBTB24 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB24
EVEXZBTB24
GoPubMedZBTB24
iHOPZBTB24
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:50:43 CET 2018

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