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ZBTB25 (zinc finger and BTB domain containing 25)

Identity

Alias_namesZNF46
C14orf51
zinc finger protein 46 (KUP)
chromosome 14 open reading frame 51
Alias_symbol (synonym)KUP
Other alias
HGNC (Hugo) ZBTB25
LocusID (NCBI) 7597
Atlas_Id 75855
Location 14q23.3  [Link to chromosome band 14q23]
Location_base_pair Starts at 64486238 and ends at 64505213 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LOC100507412 (-) / ZBTB25 (14q23.3)ZBTB25 (14q23.3) / CEP83 (12q22)ZBTB25 (14q23.3) / NME9 (3q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZBTB25   13112
Cards
Entrez_Gene (NCBI)ZBTB25  7597  zinc finger and BTB domain containing 25
AliasesC14orf51; KUP; ZNF46
GeneCards (Weizmann)ZBTB25
Ensembl hg19 (Hinxton)ENSG00000089775 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089775 [Gene_View]  chr14:64486238-64505213 [Contig_View]  ZBTB25 [Vega]
ICGC DataPortalENSG00000089775
TCGA cBioPortalZBTB25
AceView (NCBI)ZBTB25
Genatlas (Paris)ZBTB25
WikiGenes7597
SOURCE (Princeton)ZBTB25
Genetics Home Reference (NIH)ZBTB25
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB25  -     chr14:64486238-64505213 -  14q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB25  -     14q23.3   [Description]    (hg19-Feb_2009)
EnsemblZBTB25 - 14q23.3 [CytoView hg19]  ZBTB25 - 14q23.3 [CytoView hg38]
Mapping of homologs : NCBIZBTB25 [Mapview hg19]  ZBTB25 [Mapview hg38]
OMIM194541   
Gene and transcription
Genbank (Entrez)AK098181 AK313889 BC014650 BC035804 BM550005
RefSeq transcript (Entrez)NM_001304507 NM_001304508 NM_006977
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBTB25
Cluster EST : UnigeneHs.654571 [ NCBI ]
CGAP (NCI)Hs.654571
Alternative Splicing GalleryENSG00000089775
Gene ExpressionZBTB25 [ NCBI-GEO ]   ZBTB25 [ EBI - ARRAY_EXPRESS ]   ZBTB25 [ SEEK ]   ZBTB25 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB25 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7597
GTEX Portal (Tissue expression)ZBTB25
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24278   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP24278  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP24278
Splice isoforms : SwissVarP24278
PhosPhoSitePlusP24278
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB25
DMDM Disease mutations7597
Blocks (Seattle)ZBTB25
SuperfamilyP24278
Human Protein AtlasENSG00000089775
Peptide AtlasP24278
HPRD01926
IPIIPI00217777   IPI01025070   IPI01025422   
Protein Interaction databases
DIP (DOE-UCLA)P24278
IntAct (EBI)P24278
FunCoupENSG00000089775
BioGRIDZBTB25
STRING (EMBL)ZBTB25
ZODIACZBTB25
Ontologies - Pathways
QuickGOP24278
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleoplasm  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  gene expression  metal ion binding  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleoplasm  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  gene expression  metal ion binding  
NDEx NetworkZBTB25
Atlas of Cancer Signalling NetworkZBTB25
Wikipedia pathwaysZBTB25
Orthology - Evolution
OrthoDB7597
GeneTree (enSembl)ENSG00000089775
Phylogenetic Trees/Animal Genes : TreeFamZBTB25
HOVERGENP24278
HOGENOMP24278
Homologs : HomoloGeneZBTB25
Homology/Alignments : Family Browser (UCSC)ZBTB25
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB25 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB25
dbVarZBTB25
ClinVarZBTB25
1000_GenomesZBTB25 
Exome Variant ServerZBTB25
ExAC (Exome Aggregation Consortium)ZBTB25 (select the gene name)
Genetic variants : HAPMAP7597
Genomic Variants (DGV)ZBTB25 [DGVbeta]
DECIPHERZBTB25 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB25 
Mutations
ICGC Data PortalZBTB25 
TCGA Data PortalZBTB25 
Broad Tumor PortalZBTB25
OASIS PortalZBTB25 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB25  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB25
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZBTB25
DgiDB (Drug Gene Interaction Database)ZBTB25
DoCM (Curated mutations)ZBTB25 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB25 (select a term)
intoGenZBTB25
Cancer3DZBTB25(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM194541   
Orphanet
MedgenZBTB25
Genetic Testing Registry ZBTB25
NextProtP24278 [Medical]
TSGene7597
GENETestsZBTB25
Target ValidationZBTB25
Huge Navigator ZBTB25 [HugePedia]
snp3D : Map Gene to Disease7597
BioCentury BCIQZBTB25
ClinGenZBTB25
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7597
Chemical/Pharm GKB GenePA37687
Clinical trialZBTB25
Miscellaneous
canSAR (ICR)ZBTB25 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB25
EVEXZBTB25
GoPubMedZBTB25
iHOPZBTB25
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:44:06 CEST 2017

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