ZBTB32 (zinc finger and BTB domain containing 32)

2010-08-01  

Identity

HGNC
ZBTB32
LOCATION
19q13.12
LOCUSID
27033
ALIAS
FAXF,FAZF,Rog,TZFP,ZNF538

Other Information

Locus ID:

NCBI: 27033
MIM: 605859
HGNC: 16763
Ensembl: ENSG00000011590

Variants:

dbSNP: 27033
ClinVar: 27033
TCGA: ENSG00000011590
COSMIC: ZBTB32

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000011590ENST00000262630Q9Y2Y4
ENSG00000011590ENST00000392197Q9Y2Y4
ENSG00000011590ENST00000426659K7EMJ1
ENSG00000011590ENST00000481182A0A0C4DGF1

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
DNA RepairREACTOMER-HSA-73894
DNA Damage BypassREACTOMER-HSA-73893
Recognition of DNA damage by PCNA-containing replication complexREACTOMER-HSA-110314
Fanconi Anemia PathwayREACTOMER-HSA-6783310

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
201475182010Human endogenous retrovirus protein Rec interacts with the testicular zinc-finger protein and androgen receptor.30
273571542016ZBTB32 Restricts the Duration of Memory B Cell Recall Responses.13
119643102002Interactions of GATA-2 with the promyelocytic leukemia zinc finger (PLZF) protein, its homologue FAZF, and the t(11;17)-generated PLZF-retinoic acid receptor alpha oncoprotein.11
119863172002The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific.10
204938802010Insights into strand exchange in BTB domain dimers from the crystal structures of FAZF and Miz1.9
171716452007Identification of FAZF as a novel BMP2-induced transcription factor during osteoblastic differentiation.2

Citation

Dessen P

ZBTB32 (zinc finger and BTB domain containing 32)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51578/zbtb32