Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZBTB46 (zinc finger and BTB domain containing 46)

Identity

Alias_namesZNF340
BTBD4
BTB (POZ) domain containing 4
Alias_symbol (synonym)FLJ13502
RINZF
BZEL
Other aliasdJ583P15.7
dJ583P15.8
HGNC (Hugo) ZBTB46
LocusID (NCBI) 140685
Atlas_Id 75867
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 63743668 and ends at 63805503 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DYRK1A (21q22.13) / ZBTB46 (20q13.33)HEBP1 (12p13.1) / ZBTB46 (20q13.33)MYO18A (17q11.2) / ZBTB46 (20q13.33)
ZBTB46 (20q13.33) / MAFB (20q12)MYO18A ZBTB46DYRK1A ZBTB46
HEBP1 ZBTB46

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZBTB46   16094
Cards
Entrez_Gene (NCBI)ZBTB46  140685  zinc finger and BTB domain containing 46
AliasesBTBD4; BZEL; RINZF; ZNF340; 
dJ583P15.7; dJ583P15.8
GeneCards (Weizmann)ZBTB46
Ensembl hg19 (Hinxton)ENSG00000130584 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130584 [Gene_View]  chr20:63743668-63805503 [Contig_View]  ZBTB46 [Vega]
ICGC DataPortalENSG00000130584
TCGA cBioPortalZBTB46
AceView (NCBI)ZBTB46
Genatlas (Paris)ZBTB46
WikiGenes140685
SOURCE (Princeton)ZBTB46
Genetics Home Reference (NIH)ZBTB46
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB46  -     chr20:63743668-63805503 -  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB46  -     20q13.33   [Description]    (hg19-Feb_2009)
EnsemblZBTB46 - 20q13.33 [CytoView hg19]  ZBTB46 - 20q13.33 [CytoView hg38]
Mapping of homologs : NCBIZBTB46 [Mapview hg19]  ZBTB46 [Mapview hg38]
OMIM614639   
Gene and transcription
Genbank (Entrez)AK023564 AK126720 AK131482 BC052269 BC073800
RefSeq transcript (Entrez)NM_025224
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBTB46
Cluster EST : UnigeneHs.585028 [ NCBI ]
CGAP (NCI)Hs.585028
Alternative Splicing GalleryENSG00000130584
Gene ExpressionZBTB46 [ NCBI-GEO ]   ZBTB46 [ EBI - ARRAY_EXPRESS ]   ZBTB46 [ SEEK ]   ZBTB46 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB46 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140685
GTEX Portal (Tissue expression)ZBTB46
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UZ6
Splice isoforms : SwissVarQ86UZ6
PhosPhoSitePlusQ86UZ6
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB46
DMDM Disease mutations140685
Blocks (Seattle)ZBTB46
SuperfamilyQ86UZ6
Human Protein AtlasENSG00000130584
Peptide AtlasQ86UZ6
HPRD16567
IPIIPI00398152   
Protein Interaction databases
DIP (DOE-UCLA)Q86UZ6
IntAct (EBI)Q86UZ6
FunCoupENSG00000130584
BioGRIDZBTB46
STRING (EMBL)ZBTB46
ZODIACZBTB46
Ontologies - Pathways
QuickGOQ86UZ6
Ontology : AmiGOnucleic acid binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  negative regulation of granulocyte differentiation  negative regulation of macrophage differentiation  negative regulation of monocyte differentiation  metal ion binding  negative regulation of dendritic cell differentiation  positive regulation of dendritic cell differentiation  
Ontology : EGO-EBInucleic acid binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  negative regulation of granulocyte differentiation  negative regulation of macrophage differentiation  negative regulation of monocyte differentiation  metal ion binding  negative regulation of dendritic cell differentiation  positive regulation of dendritic cell differentiation  
NDEx NetworkZBTB46
Atlas of Cancer Signalling NetworkZBTB46
Wikipedia pathwaysZBTB46
Orthology - Evolution
OrthoDB140685
GeneTree (enSembl)ENSG00000130584
Phylogenetic Trees/Animal Genes : TreeFamZBTB46
HOVERGENQ86UZ6
HOGENOMQ86UZ6
Homologs : HomoloGeneZBTB46
Homology/Alignments : Family Browser (UCSC)ZBTB46
Gene fusions - Rearrangements
Fusion: TCGAMYO18A ZBTB46
Fusion: TCGADYRK1A ZBTB46
Fusion: TCGAHEBP1 ZBTB46
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB46 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB46
dbVarZBTB46
ClinVarZBTB46
1000_GenomesZBTB46 
Exome Variant ServerZBTB46
ExAC (Exome Aggregation Consortium)ZBTB46 (select the gene name)
Genetic variants : HAPMAP140685
Genomic Variants (DGV)ZBTB46 [DGVbeta]
DECIPHERZBTB46 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB46 
Mutations
ICGC Data PortalZBTB46 
TCGA Data PortalZBTB46 
Broad Tumor PortalZBTB46
OASIS PortalZBTB46 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB46  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB46
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZBTB46
DgiDB (Drug Gene Interaction Database)ZBTB46
DoCM (Curated mutations)ZBTB46 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB46 (select a term)
intoGenZBTB46
Cancer3DZBTB46(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614639   
Orphanet
MedgenZBTB46
Genetic Testing Registry ZBTB46
NextProtQ86UZ6 [Medical]
TSGene140685
GENETestsZBTB46
Target ValidationZBTB46
Huge Navigator ZBTB46 [HugePedia]
snp3D : Map Gene to Disease140685
BioCentury BCIQZBTB46
ClinGenZBTB46
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD140685
Chemical/Pharm GKB GenePA25441
Clinical trialZBTB46
Miscellaneous
canSAR (ICR)ZBTB46 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB46
EVEXZBTB46
GoPubMedZBTB46
iHOPZBTB46
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:49:28 CEST 2017

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