ZBTB49 (zinc finger and BTB domain containing 49)

2016-10-01  

Identity

HGNC
LOCATION
4p16.3
LOCUSID
ALIAS
ZNF509

Other Information

Locus ID:

NCBI: 166793
MIM: 616238
HGNC: 19883
Ensembl: ENSG00000168826

Variants:

dbSNP: 166793
ClinVar: 166793
TCGA: ENSG00000168826
COSMIC: ZBTB49

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168826ENST00000337872Q6ZSB9
ENSG00000168826ENST00000502918D6RJ00
ENSG00000168826ENST00000503703D6RB16
ENSG00000168826ENST00000504302H0Y8P2
ENSG00000168826ENST00000511458H0YAD4
ENSG00000168826ENST00000515012D6RC96

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
252459462014Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress.4
287573842017ZNF509S1 downregulates PUMA by inhibiting p53K382 acetylation and p53-DNA binding.1

Citation

Dessen P

ZBTB49 (zinc finger and BTB domain containing 49)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56245/zbtb49