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ZBTB49 (zinc finger and BTB domain containing 49)

Identity

Alias_namesZNF509
zinc finger protein 509
Alias_symbol (synonym)FLJ38559
Other alias
HGNC (Hugo) ZBTB49
LocusID (NCBI) 166793
Atlas_Id 56245
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 4290197 and ends at 4321786 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZBTB49   19883
Cards
Entrez_Gene (NCBI)ZBTB49  166793  zinc finger and BTB domain containing 49
AliasesZNF509
GeneCards (Weizmann)ZBTB49
Ensembl hg19 (Hinxton)ENSG00000168826 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168826 [Gene_View]  ENSG00000168826 [Sequence]  chr4:4290197-4321786 [Contig_View]  ZBTB49 [Vega]
ICGC DataPortalENSG00000168826
TCGA cBioPortalZBTB49
AceView (NCBI)ZBTB49
Genatlas (Paris)ZBTB49
WikiGenes166793
SOURCE (Princeton)ZBTB49
Genetics Home Reference (NIH)ZBTB49
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB49  -     chr4:4290197-4321786 +  4p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB49  -     4p16.3   [Description]    (hg19-Feb_2009)
EnsemblZBTB49 - 4p16.3 [CytoView hg19]  ZBTB49 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBIZBTB49 [Mapview hg19]  ZBTB49 [Mapview hg38]
OMIM616238   
Gene and transcription
Genbank (Entrez)AB209466 AK095878 AK127560 AK292551 AL832751
RefSeq transcript (Entrez)NM_001330625 NM_145291
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBTB49
Cluster EST : UnigeneHs.419997 [ NCBI ]
CGAP (NCI)Hs.419997
Alternative Splicing GalleryENSG00000168826
Gene ExpressionZBTB49 [ NCBI-GEO ]   ZBTB49 [ EBI - ARRAY_EXPRESS ]   ZBTB49 [ SEEK ]   ZBTB49 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB49 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)166793
GTEX Portal (Tissue expression)ZBTB49
Human Protein AtlasENSG00000168826-ZBTB49 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZSB9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZSB9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZSB9
Splice isoforms : SwissVarQ6ZSB9
PhosPhoSitePlusQ6ZSB9
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB49
DMDM Disease mutations166793
Blocks (Seattle)ZBTB49
SuperfamilyQ6ZSB9
Human Protein Atlas [tissue]ENSG00000168826-ZBTB49 [tissue]
Peptide AtlasQ6ZSB9
HPRD10335
IPIIPI00152157   IPI00554487   IPI01011379   IPI00963830   IPI00964532   IPI00965697   IPI00964124   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZSB9
IntAct (EBI)Q6ZSB9
FunCoupENSG00000168826
BioGRIDZBTB49
STRING (EMBL)ZBTB49
ZODIACZBTB49
Ontologies - Pathways
QuickGOQ6ZSB9
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  transcription coactivator binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cell cycle arrest  transcription factor binding  negative regulation of cell proliferation  microtubule cytoskeleton  sequence-specific DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific  transcription coactivator binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cell cycle arrest  transcription factor binding  negative regulation of cell proliferation  microtubule cytoskeleton  sequence-specific DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZBTB49
Atlas of Cancer Signalling NetworkZBTB49
Wikipedia pathwaysZBTB49
Orthology - Evolution
OrthoDB166793
GeneTree (enSembl)ENSG00000168826
Phylogenetic Trees/Animal Genes : TreeFamZBTB49
HOVERGENQ6ZSB9
HOGENOMQ6ZSB9
Homologs : HomoloGeneZBTB49
Homology/Alignments : Family Browser (UCSC)ZBTB49
Gene fusions - Rearrangements
Fusion : QuiverZBTB49
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB49 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB49
dbVarZBTB49
ClinVarZBTB49
1000_GenomesZBTB49 
Exome Variant ServerZBTB49
ExAC (Exome Aggregation Consortium)ENSG00000168826
GNOMAD BrowserENSG00000168826
Varsome BrowserZBTB49
Genetic variants : HAPMAP166793
Genomic Variants (DGV)ZBTB49 [DGVbeta]
DECIPHERZBTB49 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB49 
Mutations
ICGC Data PortalZBTB49 
TCGA Data PortalZBTB49 
Broad Tumor PortalZBTB49
OASIS PortalZBTB49 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB49  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB49
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZBTB49
DgiDB (Drug Gene Interaction Database)ZBTB49
DoCM (Curated mutations)ZBTB49 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB49 (select a term)
intoGenZBTB49
Cancer3DZBTB49(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616238   
Orphanet
DisGeNETZBTB49
MedgenZBTB49
Genetic Testing Registry ZBTB49
NextProtQ6ZSB9 [Medical]
TSGene166793
GENETestsZBTB49
Target ValidationZBTB49
Huge Navigator ZBTB49 [HugePedia]
snp3D : Map Gene to Disease166793
BioCentury BCIQZBTB49
ClinGenZBTB49
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD166793
Chemical/Pharm GKB GenePA165664822
Clinical trialZBTB49
Miscellaneous
canSAR (ICR)ZBTB49 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB49
EVEXZBTB49
GoPubMedZBTB49
iHOPZBTB49
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:50:45 CET 2018

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