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ZBTB5 (zinc finger and BTB domain containing 5)

Identity

Alias_symbol (synonym)KIAA0354
Other alias-
HGNC (Hugo) ZBTB5
LocusID (NCBI) 9925
Atlas_Id 53060
Location 9p13.2  [Link to chromosome band 9p13]
Location_base_pair Starts at 37438100 and ends at 37465407 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CSNK1A1 (5q32) / ZBTB5 (9p13.2)MYC (8q24.21) / ZBTB5 (9p13.2)VSTM2L (20q11.23) / ZBTB5 (9p13.2)
ZBTB5 (9p13.2) / ZBTB5 (9p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(8;9)(q24;p13) ?/MYC


External links

Nomenclature
HGNC (Hugo)ZBTB5   23836
Cards
Entrez_Gene (NCBI)ZBTB5  9925  zinc finger and BTB domain containing 5
Aliases
GeneCards (Weizmann)ZBTB5
Ensembl hg19 (Hinxton)ENSG00000168795 [Gene_View]  chr9:37438100-37465407 [Contig_View]  ZBTB5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000168795 [Gene_View]  chr9:37438100-37465407 [Contig_View]  ZBTB5 [Vega]
ICGC DataPortalENSG00000168795
TCGA cBioPortalZBTB5
AceView (NCBI)ZBTB5
Genatlas (Paris)ZBTB5
WikiGenes9925
SOURCE (Princeton)ZBTB5
Genetics Home Reference (NIH)ZBTB5
Genomic and cartography
GoldenPath hg19 (UCSC)ZBTB5  -     chr9:37438100-37465407 -  9p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZBTB5  -     9p13.2   [Description]    (hg38-Dec_2013)
EnsemblZBTB5 - 9p13.2 [CytoView hg19]  ZBTB5 - 9p13.2 [CytoView hg38]
Mapping of homologs : NCBIZBTB5 [Mapview hg19]  ZBTB5 [Mapview hg38]
OMIM616590   
Gene and transcription
Genbank (Entrez)AB002352 AK292404 AW075599 BC010007 DB457364
RefSeq transcript (Entrez)NM_014872
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008413 NW_004929342
Consensus coding sequences : CCDS (NCBI)ZBTB5
Cluster EST : UnigeneHs.161276 [ NCBI ]
CGAP (NCI)Hs.161276
Alternative Splicing GalleryENSG00000168795
Gene ExpressionZBTB5 [ NCBI-GEO ]   ZBTB5 [ EBI - ARRAY_EXPRESS ]   ZBTB5 [ SEEK ]   ZBTB5 [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9925
GTEX Portal (Tissue expression)ZBTB5
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15062   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15062  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15062
Splice isoforms : SwissVarO15062
PhosPhoSitePlusO15062
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB5
DMDM Disease mutations9925
Blocks (Seattle)ZBTB5
SuperfamilyO15062
Human Protein AtlasENSG00000168795
Peptide AtlasO15062
HPRD08829
IPIIPI00006671   
Protein Interaction databases
DIP (DOE-UCLA)O15062
IntAct (EBI)O15062
FunCoupENSG00000168795
BioGRIDZBTB5
STRING (EMBL)ZBTB5
ZODIACZBTB5
Ontologies - Pathways
QuickGOO15062
Ontology : AmiGODNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZBTB5
Atlas of Cancer Signalling NetworkZBTB5
Wikipedia pathwaysZBTB5
Orthology - Evolution
OrthoDB9925
GeneTree (enSembl)ENSG00000168795
Phylogenetic Trees/Animal Genes : TreeFamZBTB5
HOVERGENO15062
HOGENOMO15062
Homologs : HomoloGeneZBTB5
Homology/Alignments : Family Browser (UCSC)ZBTB5
Gene fusions - Rearrangements
Fusion : MitelmanMYC/ZBTB5 [8q24.21/9p13.2]  [t(8;9)(q24;p13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB5
dbVarZBTB5
ClinVarZBTB5
1000_GenomesZBTB5 
Exome Variant ServerZBTB5
ExAC (Exome Aggregation Consortium)ZBTB5 (select the gene name)
Genetic variants : HAPMAP9925
Genomic Variants (DGV)ZBTB5 [DGVbeta]
DECIPHER (Syndromes)9:37438100-37465407  ENSG00000168795
CONAN: Copy Number AnalysisZBTB5 
Mutations
ICGC Data PortalZBTB5 
TCGA Data PortalZBTB5 
Broad Tumor PortalZBTB5
OASIS PortalZBTB5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZBTB5
DgiDB (Drug Gene Interaction Database)ZBTB5
DoCM (Curated mutations)ZBTB5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB5 (select a term)
intoGenZBTB5
Cancer3DZBTB5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616590   
Orphanet
MedgenZBTB5
Genetic Testing Registry ZBTB5
NextProtO15062 [Medical]
TSGene9925
GENETestsZBTB5
Huge Navigator ZBTB5 [HugePedia]
snp3D : Map Gene to Disease9925
BioCentury BCIQZBTB5
ClinGenZBTB5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9925
Chemical/Pharm GKB GenePA134969268
Clinical trialZBTB5
Miscellaneous
canSAR (ICR)ZBTB5 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB5
EVEXZBTB5
GoPubMedZBTB5
iHOPZBTB5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:25:24 CEST 2017

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