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ZBTB7C (zinc finger and BTB domain containing 7C)

Identity

Alias_namesZBTB36
zinc finger and BTB domain containing 36
Alias_symbol (synonym)ZNF857C
Other aliasAPM-1
APM1
HGNC (Hugo) ZBTB7C
LocusID (NCBI) 201501
Atlas_Id 52695
Location 18q21.1  [Link to chromosome band 18q21]
Location_base_pair Starts at 48027268 and ends at 48137309 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CTNNAL1 (9q31.3) / ZBTB7C (18q21.1)HCG25 (6p21.32) / ZBTB7C (18q21.1)PIGM (1q23.2) / ZBTB7C (18q21.1)
SMAD2 (18q21.1) / ZBTB7C (18q21.1)ZBTB7C (18q21.1) / FBXO15 (18q22.3)ZCCHC7 (9p13.2) / ZBTB7C (18q21.1)
SMAD2 18q21.1 / ZBTB7C 18q21.1ZBTB7C 18q21.1 / FBXO15 18q22.3ZCCHC7 9p13.2 / ZBTB7C 18q21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZBTB7C   31700
Cards
Entrez_Gene (NCBI)ZBTB7C  201501  zinc finger and BTB domain containing 7C
AliasesAPM-1; APM1; ZBTB36; ZNF857C
GeneCards (Weizmann)ZBTB7C
Ensembl hg19 (Hinxton)ENSG00000184828 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184828 [Gene_View]  chr18:48027268-48137309 [Contig_View]  ZBTB7C [Vega]
ICGC DataPortalENSG00000184828
TCGA cBioPortalZBTB7C
AceView (NCBI)ZBTB7C
Genatlas (Paris)ZBTB7C
WikiGenes201501
SOURCE (Princeton)ZBTB7C
Genetics Home Reference (NIH)ZBTB7C
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB7C  -     chr18:48027268-48137309 -  18q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB7C  -     18q21.1   [Description]    (hg19-Feb_2009)
EnsemblZBTB7C - 18q21.1 [CytoView hg19]  ZBTB7C - 18q21.1 [CytoView hg38]
Mapping of homologs : NCBIZBTB7C [Mapview hg19]  ZBTB7C [Mapview hg38]
OMIM616591   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001039360 NM_001318841
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBTB7C
Cluster EST : UnigeneHs.732162 [ NCBI ]
CGAP (NCI)Hs.732162
Alternative Splicing GalleryENSG00000184828
Gene ExpressionZBTB7C [ NCBI-GEO ]   ZBTB7C [ EBI - ARRAY_EXPRESS ]   ZBTB7C [ SEEK ]   ZBTB7C [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB7C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)201501
GTEX Portal (Tissue expression)ZBTB7C
Protein : pattern, domain, 3D structure
UniProt/SwissProtA1YPR0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA1YPR0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA1YPR0
Splice isoforms : SwissVarA1YPR0
PhosPhoSitePlusA1YPR0
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)ARM-type_fold    BTB/POZ_dom    SKP1/BTB/POZ    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB7C
DMDM Disease mutations201501
Blocks (Seattle)ZBTB7C
SuperfamilyA1YPR0
Human Protein AtlasENSG00000184828
Peptide AtlasA1YPR0
IPIIPI00719277   IPI01012527   IPI01013263   
Protein Interaction databases
DIP (DOE-UCLA)A1YPR0
IntAct (EBI)A1YPR0
FunCoupENSG00000184828
BioGRIDZBTB7C
STRING (EMBL)ZBTB7C
ZODIACZBTB7C
Ontologies - Pathways
QuickGOA1YPR0
Ontology : AmiGOnucleic acid binding  nucleus  positive regulation of fat cell differentiation  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  regulation of RNA polymerase II regulatory region sequence-specific DNA binding  
Ontology : EGO-EBInucleic acid binding  nucleus  positive regulation of fat cell differentiation  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  regulation of RNA polymerase II regulatory region sequence-specific DNA binding  
NDEx NetworkZBTB7C
Atlas of Cancer Signalling NetworkZBTB7C
Wikipedia pathwaysZBTB7C
Orthology - Evolution
OrthoDB201501
GeneTree (enSembl)ENSG00000184828
Phylogenetic Trees/Animal Genes : TreeFamZBTB7C
HOVERGENA1YPR0
HOGENOMA1YPR0
Homologs : HomoloGeneZBTB7C
Homology/Alignments : Family Browser (UCSC)ZBTB7C
Gene fusions - Rearrangements
Fusion : MitelmanSMAD2/ZBTB7C [18q21.1/18q21.1]  [t(18;18)(q21;q21)]  
Fusion : MitelmanZBTB7C/FBXO15 [18q21.1/18q22.3]  [t(18;18)(q21;q22)]  
Fusion : MitelmanZCCHC7/ZBTB7C [9p13.2/18q21.1]  [t(9;18)(p13;q21)]  
Fusion: TCGASMAD2 18q21.1 ZBTB7C 18q21.1 BRCA
Fusion: TCGAZBTB7C 18q21.1 FBXO15 18q22.3 LGG
Fusion: TCGAZCCHC7 9p13.2 ZBTB7C 18q21.1 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB7C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB7C
dbVarZBTB7C
ClinVarZBTB7C
1000_GenomesZBTB7C 
Exome Variant ServerZBTB7C
ExAC (Exome Aggregation Consortium)ZBTB7C (select the gene name)
Genetic variants : HAPMAP201501
Genomic Variants (DGV)ZBTB7C [DGVbeta]
DECIPHERZBTB7C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB7C 
Mutations
ICGC Data PortalZBTB7C 
TCGA Data PortalZBTB7C 
Broad Tumor PortalZBTB7C
OASIS PortalZBTB7C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB7C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB7C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZBTB7C
DgiDB (Drug Gene Interaction Database)ZBTB7C
DoCM (Curated mutations)ZBTB7C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB7C (select a term)
intoGenZBTB7C
Cancer3DZBTB7C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616591   
Orphanet
MedgenZBTB7C
Genetic Testing Registry ZBTB7C
NextProtA1YPR0 [Medical]
TSGene201501
GENETestsZBTB7C
Target ValidationZBTB7C
Huge Navigator ZBTB7C [HugePedia]
snp3D : Map Gene to Disease201501
BioCentury BCIQZBTB7C
ClinGenZBTB7C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD201501
Chemical/Pharm GKB GenePA134861865
Clinical trialZBTB7C
Miscellaneous
canSAR (ICR)ZBTB7C (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB7C
EVEXZBTB7C
GoPubMedZBTB7C
iHOPZBTB7C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Aug 1 17:19:12 CEST 2017

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