Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZBTB8B (zinc finger and BTB domain containing 8B)

Identity

Alias_symbol (synonym)RP1-27O5.1
DKFZp547H154
ZNF916B
Other alias
HGNC (Hugo) ZBTB8B
LocusID (NCBI) 728116
Atlas_Id 54790
Location 1p35.1  [Link to chromosome band 1p35]
Location_base_pair Starts at 32465057 and ends at 32487858 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ORAOV1 (11q13.3) / ZBTB8B (1p35.1)ZBTB8B (1p35.1) / CDH12 (5p14.3)ZBTB8B (1p35.1) / TRAF3IP1 (2q37.3)
ZBTB8B (1p35.1) / XYLT1 (16p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ZBTB8B   37057
Cards
Entrez_Gene (NCBI)ZBTB8B  728116  zinc finger and BTB domain containing 8B
AliasesZNF916B
GeneCards (Weizmann)ZBTB8B
Ensembl hg19 (Hinxton)ENSG00000273274 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000273274 [Gene_View]  chr1:32465057-32487858 [Contig_View]  ZBTB8B [Vega]
ICGC DataPortalENSG00000273274
TCGA cBioPortalZBTB8B
AceView (NCBI)ZBTB8B
Genatlas (Paris)ZBTB8B
WikiGenes728116
SOURCE (Princeton)ZBTB8B
Genetics Home Reference (NIH)ZBTB8B
Genomic and cartography
GoldenPath hg38 (UCSC)ZBTB8B  -     chr1:32465057-32487858 +  1p35.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZBTB8B  -     1p35.1   [Description]    (hg19-Feb_2009)
EnsemblZBTB8B - 1p35.1 [CytoView hg19]  ZBTB8B - 1p35.1 [CytoView hg38]
Mapping of homologs : NCBIZBTB8B [Mapview hg19]  ZBTB8B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AL442095
RefSeq transcript (Entrez)NM_001145720
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZBTB8B
Cluster EST : UnigeneHs.647658 [ NCBI ]
CGAP (NCI)Hs.647658
Alternative Splicing GalleryENSG00000273274
Gene ExpressionZBTB8B [ NCBI-GEO ]   ZBTB8B [ EBI - ARRAY_EXPRESS ]   ZBTB8B [ SEEK ]   ZBTB8B [ MEM ]
Gene Expression Viewer (FireBrowse)ZBTB8B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)728116
GTEX Portal (Tissue expression)ZBTB8B
Human Protein AtlasENSG00000273274-ZBTB8B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NAP8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NAP8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NAP8
Splice isoforms : SwissVarQ8NAP8
PhosPhoSitePlusQ8NAP8
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)BTB (PF00651)   
Domain families : Pfam (NCBI)pfam00651   
Domain families : Smart (EMBL)BTB (SM00225)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZBTB8B
DMDM Disease mutations728116
Blocks (Seattle)ZBTB8B
SuperfamilyQ8NAP8
Human Protein Atlas [tissue]ENSG00000273274-ZBTB8B [tissue]
Peptide AtlasQ8NAP8
IPIIPI00940688   IPI00168061   
Protein Interaction databases
DIP (DOE-UCLA)Q8NAP8
IntAct (EBI)Q8NAP8
FunCoupENSG00000273274
BioGRIDZBTB8B
STRING (EMBL)ZBTB8B
ZODIACZBTB8B
Ontologies - Pathways
QuickGOQ8NAP8
Ontology : AmiGODNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZBTB8B
Atlas of Cancer Signalling NetworkZBTB8B
Wikipedia pathwaysZBTB8B
Orthology - Evolution
OrthoDB728116
GeneTree (enSembl)ENSG00000273274
Phylogenetic Trees/Animal Genes : TreeFamZBTB8B
HOVERGENQ8NAP8
HOGENOMQ8NAP8
Homologs : HomoloGeneZBTB8B
Homology/Alignments : Family Browser (UCSC)ZBTB8B
Gene fusions - Rearrangements
Fusion : MitelmanZBTB8B/TRAF3IP1 [1p35.1/2q37.3]  
Tumor Fusion PortalZBTB8B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZBTB8B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZBTB8B
dbVarZBTB8B
ClinVarZBTB8B
1000_GenomesZBTB8B 
Exome Variant ServerZBTB8B
ExAC (Exome Aggregation Consortium)ENSG00000273274
GNOMAD BrowserENSG00000273274
Genetic variants : HAPMAP728116
Genomic Variants (DGV)ZBTB8B [DGVbeta]
DECIPHERZBTB8B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZBTB8B 
Mutations
ICGC Data PortalZBTB8B 
TCGA Data PortalZBTB8B 
Broad Tumor PortalZBTB8B
OASIS PortalZBTB8B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZBTB8B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZBTB8B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZBTB8B
DgiDB (Drug Gene Interaction Database)ZBTB8B
DoCM (Curated mutations)ZBTB8B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZBTB8B (select a term)
intoGenZBTB8B
Cancer3DZBTB8B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZBTB8B
MedgenZBTB8B
Genetic Testing Registry ZBTB8B
NextProtQ8NAP8 [Medical]
TSGene728116
GENETestsZBTB8B
Target ValidationZBTB8B
Huge Navigator ZBTB8B [HugePedia]
snp3D : Map Gene to Disease728116
BioCentury BCIQZBTB8B
ClinGenZBTB8B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD728116
Chemical/Pharm GKB GenePA164727642
Clinical trialZBTB8B
Miscellaneous
canSAR (ICR)ZBTB8B (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZBTB8B
EVEXZBTB8B
GoPubMedZBTB8B
iHOPZBTB8B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:42:08 CET 2017

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