Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZC3H12D (zinc finger CCCH-type containing 12D)

Identity

Alias_namesC6orf95
chromosome 6 open reading frame 95
Alias_symbol (synonym)dJ281H8.1
MCPIP4
Other aliasTFL
p34
HGNC (Hugo) ZC3H12D
LocusID (NCBI) 340152
Atlas_Id 53061
Location 6q25.1  [Link to chromosome band 6q25]
Location_base_pair Starts at 149447630 and ends at 149485012 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IGK (14q32.33) / ZC3H12D (6q25.1)ZC3H12D (6q25.1) / UST (6q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(2;6)(p11;q25) IGK/ZC3H12D


External links

Nomenclature
HGNC (Hugo)ZC3H12D   21175
Cards
Entrez_Gene (NCBI)ZC3H12D  340152  zinc finger CCCH-type containing 12D
AliasesC6orf95; MCPIP4; TFL; dJ281H8.1; 
p34
GeneCards (Weizmann)ZC3H12D
Ensembl hg19 (Hinxton)ENSG00000178199 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178199 [Gene_View]  ENSG00000178199 [Sequence]  chr6:149447630-149485012 [Contig_View]  ZC3H12D [Vega]
ICGC DataPortalENSG00000178199
TCGA cBioPortalZC3H12D
AceView (NCBI)ZC3H12D
Genatlas (Paris)ZC3H12D
WikiGenes340152
SOURCE (Princeton)ZC3H12D
Genetics Home Reference (NIH)ZC3H12D
Genomic and cartography
GoldenPath hg38 (UCSC)ZC3H12D  -     chr6:149447630-149485012 -  6q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZC3H12D  -     6q25.1   [Description]    (hg19-Feb_2009)
EnsemblZC3H12D - 6q25.1 [CytoView hg19]  ZC3H12D - 6q25.1 [CytoView hg38]
Mapping of homologs : NCBIZC3H12D [Mapview hg19]  ZC3H12D [Mapview hg38]
OMIM611106   
Gene and transcription
Genbank (Entrez)AB458221 AB458222 AK090441 AK127932 BC127762
RefSeq transcript (Entrez)NM_207360
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZC3H12D
Cluster EST : UnigeneHs.632618 [ NCBI ]
CGAP (NCI)Hs.632618
Alternative Splicing GalleryENSG00000178199
Gene ExpressionZC3H12D [ NCBI-GEO ]   ZC3H12D [ EBI - ARRAY_EXPRESS ]   ZC3H12D [ SEEK ]   ZC3H12D [ MEM ]
Gene Expression Viewer (FireBrowse)ZC3H12D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)340152
GTEX Portal (Tissue expression)ZC3H12D
Human Protein AtlasENSG00000178199-ZC3H12D [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA2A288   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA2A288  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA2A288
Splice isoforms : SwissVarA2A288
Catalytic activity : Enzyme3.1.-.- [ Enzyme-Expasy ]   3.1.-.-3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   
PhosPhoSitePlusA2A288
Domaine pattern : Prosite (Expaxy)ZF_C3H1 (PS50103)   
Domains : Interpro (EBI)RNase_Zc3h12_NYN    Znf_CCCH   
Domain families : Pfam (Sanger)RNase_Zc3h12a (PF11977)   
Domain families : Pfam (NCBI)pfam11977   
Conserved Domain (NCBI)ZC3H12D
DMDM Disease mutations340152
Blocks (Seattle)ZC3H12D
SuperfamilyA2A288
Human Protein Atlas [tissue]ENSG00000178199-ZC3H12D [tissue]
Peptide AtlasA2A288
IPIIPI00854887   IPI01009660   IPI00943634   IPI00168748   IPI00922370   IPI00916771   
Protein Interaction databases
DIP (DOE-UCLA)A2A288
IntAct (EBI)A2A288
FunCoupENSG00000178199
BioGRIDZC3H12D
STRING (EMBL)ZC3H12D
ZODIACZC3H12D
Ontologies - Pathways
QuickGOA2A288
Ontology : AmiGOP-body  endonuclease activity  protein binding  nucleoplasm  cytoplasmic ribonucleoprotein granule  metal ion binding  3'-UTR-mediated mRNA destabilization  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBIP-body  endonuclease activity  protein binding  nucleoplasm  cytoplasmic ribonucleoprotein granule  metal ion binding  3'-UTR-mediated mRNA destabilization  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkZC3H12D
Atlas of Cancer Signalling NetworkZC3H12D
Wikipedia pathwaysZC3H12D
Orthology - Evolution
OrthoDB340152
GeneTree (enSembl)ENSG00000178199
Phylogenetic Trees/Animal Genes : TreeFamZC3H12D
HOVERGENA2A288
HOGENOMA2A288
Homologs : HomoloGeneZC3H12D
Homology/Alignments : Family Browser (UCSC)ZC3H12D
Gene fusions - Rearrangements
Fusion : MitelmanIGK/ZC3H12D [2p11.2/6q25.1]  [t(2;6)(p11;q25)]  
Fusion : QuiverZC3H12D
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZC3H12D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZC3H12D
dbVarZC3H12D
ClinVarZC3H12D
1000_GenomesZC3H12D 
Exome Variant ServerZC3H12D
ExAC (Exome Aggregation Consortium)ENSG00000178199
GNOMAD BrowserENSG00000178199
Varsome BrowserZC3H12D
Genetic variants : HAPMAP340152
Genomic Variants (DGV)ZC3H12D [DGVbeta]
DECIPHERZC3H12D [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZC3H12D 
Mutations
ICGC Data PortalZC3H12D 
TCGA Data PortalZC3H12D 
Broad Tumor PortalZC3H12D
OASIS PortalZC3H12D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZC3H12D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZC3H12D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZC3H12D
DgiDB (Drug Gene Interaction Database)ZC3H12D
DoCM (Curated mutations)ZC3H12D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZC3H12D (select a term)
intoGenZC3H12D
Cancer3DZC3H12D(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611106   
Orphanet
DisGeNETZC3H12D
MedgenZC3H12D
Genetic Testing Registry ZC3H12D
NextProtA2A288 [Medical]
TSGene340152
GENETestsZC3H12D
Target ValidationZC3H12D
Huge Navigator ZC3H12D [HugePedia]
snp3D : Map Gene to Disease340152
BioCentury BCIQZC3H12D
ClinGenZC3H12D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD340152
Chemical/Pharm GKB GenePA134867170
Clinical trialZC3H12D
Miscellaneous
canSAR (ICR)ZC3H12D (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZC3H12D
EVEXZC3H12D
GoPubMedZC3H12D
iHOPZC3H12D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:50:48 CET 2018

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