Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZC3H13 (zinc finger CCCH-type containing 13)

Identity

Alias (NCBI)KIAA0853
Xio
HGNC (Hugo) ZC3H13
HGNC Alias symbDKFZp434D1812
HGNC Previous nameKIAA0853
HGNC Previous nameKIAA0853
LocusID (NCBI) 23091
Atlas_Id 75880
Location 13q14.13  [Link to chromosome band 13q14]
Location_base_pair Starts at 45962176 and ends at 46052746 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IVNS1ABP (1q25.3) / ZC3H13 (13q14.13)KMT2A (11q23.3) / ZC3H13 (13q14.13)NFE2L2 (2q31.2) / ZC3H13 (13q14.13)
PRRC2C (1q24.3) / ZC3H13 (13q14.13)SNX6 (14q13.1) / ZC3H13 (13q14.13)ZC3H13 (13q14.13) / FAM96A (15q22.31)
ZC3H13 (13q14.13) / TMEM232 (5q22.1)ZC3H13 (13q14.13) / ZC3H13 (13q14.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(11;13)(q23;q14) KMT2A/ZC3H13
t(11;13)(q23;q14) KMT2A/ZC3H13


External links

Nomenclature
HGNC (Hugo)ZC3H13   20368
Cards
Entrez_Gene (NCBI)ZC3H13    zinc finger CCCH-type containing 13
AliasesKIAA0853; Xio
GeneCards (Weizmann)ZC3H13
Ensembl hg19 (Hinxton)ENSG00000123200 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123200 [Gene_View]  ENSG00000123200 [Sequence]  chr13:45962176-46052746 [Contig_View]  ZC3H13 [Vega]
ICGC DataPortalENSG00000123200
TCGA cBioPortalZC3H13
AceView (NCBI)ZC3H13
Genatlas (Paris)ZC3H13
SOURCE (Princeton)ZC3H13
Genetics Home Reference (NIH)ZC3H13
Genomic and cartography
GoldenPath hg38 (UCSC)ZC3H13  -     chr13:45962176-46052746 -  13q14.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZC3H13  -     13q14.13   [Description]    (hg19-Feb_2009)
GoldenPathZC3H13 - 13q14.13 [CytoView hg19]  ZC3H13 - 13q14.13 [CytoView hg38]
ImmunoBaseENSG00000123200
genome Data Viewer NCBIZC3H13 [Mapview hg19]  
OMIM616453   
Gene and transcription
Genbank (Entrez)AB020660 AI640521 AK001815 AK056422 AK074924
RefSeq transcript (Entrez)NM_001076788 NM_001330564 NM_001330565 NM_001330566 NM_001330567 NM_001382206 NM_001382207 NM_001382208 NM_001382209 NM_001382210 NM_001382211 NM_001382212 NM_001382213 NM_001382214 NM_015070
Consensus coding sequences : CCDS (NCBI)ZC3H13
Alternative Splicing GalleryENSG00000123200
Gene ExpressionZC3H13 [ NCBI-GEO ]   ZC3H13 [ EBI - ARRAY_EXPRESS ]   ZC3H13 [ SEEK ]   ZC3H13 [ MEM ]
Gene Expression Viewer (FireBrowse)ZC3H13 [ Firebrowse - Broad ]
GenevisibleExpression of ZC3H13 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23091
GTEX Portal (Tissue expression)ZC3H13
Human Protein AtlasENSG00000123200-ZC3H13 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T200   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T200  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T200
PhosPhoSitePlusQ5T200
Domaine pattern : Prosite (Expaxy)ZF_C3H1 (PS50103)   
Domains : Interpro (EBI)Znf_CCCH    Znf_CCCH_sf   
Domain families : Pfam (Sanger)zf-CCCH (PF00642)   
Domain families : Pfam (NCBI)pfam00642   
Domain families : Smart (EMBL)ZnF_C3H1 (SM00356)  
Conserved Domain (NCBI)ZC3H13
SuperfamilyQ5T200
AlphaFold pdb e-kbQ5T200   
Human Protein Atlas [tissue]ENSG00000123200-ZC3H13 [tissue]
HPRD08307
Protein Interaction databases
DIP (DOE-UCLA)Q5T200
IntAct (EBI)Q5T200
BioGRIDZC3H13
STRING (EMBL)ZC3H13
ZODIACZC3H13
Ontologies - Pathways
QuickGOQ5T200
Ontology : AmiGORNA binding  protein binding  nucleoplasm  mRNA processing  multicellular organism development  RNA splicing  nuclear speck  nuclear speck  RNA N6-methyladenosine methyltransferase complex  metal ion binding  mRNA methylation  regulation of stem cell population maintenance  
Ontology : EGO-EBIRNA binding  protein binding  nucleoplasm  mRNA processing  multicellular organism development  RNA splicing  nuclear speck  nuclear speck  RNA N6-methyladenosine methyltransferase complex  metal ion binding  mRNA methylation  regulation of stem cell population maintenance  
NDEx NetworkZC3H13
Atlas of Cancer Signalling NetworkZC3H13
Wikipedia pathwaysZC3H13
Orthology - Evolution
OrthoDB23091
GeneTree (enSembl)ENSG00000123200
Phylogenetic Trees/Animal Genes : TreeFamZC3H13
Homologs : HomoloGeneZC3H13
Homology/Alignments : Family Browser (UCSC)ZC3H13
Gene fusions - Rearrangements
Fusion : QuiverZC3H13
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZC3H13 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZC3H13
dbVarZC3H13
ClinVarZC3H13
MonarchZC3H13
1000_GenomesZC3H13 
Exome Variant ServerZC3H13
GNOMAD BrowserENSG00000123200
Varsome BrowserZC3H13
Genomic Variants (DGV)ZC3H13 [DGVbeta]
DECIPHERZC3H13 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZC3H13 
Mutations
ICGC Data PortalZC3H13 
TCGA Data PortalZC3H13 
Broad Tumor PortalZC3H13
OASIS PortalZC3H13 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZC3H13  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZC3H13
Mutations and Diseases : HGMDZC3H13
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutasearch ZC3H13
DgiDB (Drug Gene Interaction Database)ZC3H13
DoCM (Curated mutations)ZC3H13 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZC3H13 (select a term)
Cancer3DZC3H13(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616453   
Orphanet
DisGeNETZC3H13
MedgenZC3H13
Genetic Testing Registry ZC3H13
NextProtQ5T200 [Medical]
GENETestsZC3H13
Target ValidationZC3H13
Huge Navigator ZC3H13 [HugePedia]
ClinGenZC3H13
Clinical trials, drugs, therapy
MyCancerGenomeZC3H13
Protein Interactions : CTDZC3H13
Pharm GKB GenePA134907656
PharosQ5T200
Clinical trialZC3H13
Miscellaneous
canSAR (ICR)ZC3H13
HarmonizomeZC3H13
DataMed IndexZC3H13
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZC3H13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Sep 15 23:37:13 CEST 2021

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