Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZC3H3 (zinc finger CCCH-type containing 3)

Identity

Alias_namesZC3HDC3
zinc finger CCCH-type domain containing 3
Alias_symbol (synonym)KIAA0150
Other alias
HGNC (Hugo) ZC3H3
LocusID (NCBI) 23144
Atlas_Id 75884
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 143437655 and ends at 143541450 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EZH1 (17q21.2) / ZC3H3 (8q24.3)ZC3H3 (8q24.3) / EEF1D (8q24.3)ZC3H3 (8q24.3) / KIAA0907 (1q22)
ZC3H3 (8q24.3) / KLK3 (19q13.33)ZC3H3 (8q24.3) / PYCRL (8q24.3)ZC3H3 (8q24.3) / YY1 (14q32.2)
ZNF696 (8q24.3) / ZC3H3 (8q24.3)ZC3H3 YY1ZC3H3 KLK3
ZC3H3 KIAA0907ZC3H3 PYCRL

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZC3H3   28972
Cards
Entrez_Gene (NCBI)ZC3H3  23144  zinc finger CCCH-type containing 3
AliasesZC3HDC3
GeneCards (Weizmann)ZC3H3
Ensembl hg19 (Hinxton)ENSG00000014164 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000014164 [Gene_View]  chr8:143437655-143541450 [Contig_View]  ZC3H3 [Vega]
ICGC DataPortalENSG00000014164
TCGA cBioPortalZC3H3
AceView (NCBI)ZC3H3
Genatlas (Paris)ZC3H3
WikiGenes23144
SOURCE (Princeton)ZC3H3
Genetics Home Reference (NIH)ZC3H3
Genomic and cartography
GoldenPath hg38 (UCSC)ZC3H3  -     chr8:143437655-143541450 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZC3H3  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblZC3H3 - 8q24.3 [CytoView hg19]  ZC3H3 - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBIZC3H3 [Mapview hg19]  ZC3H3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA806585 BC038670 BM148116 D63484 DQ583219
RefSeq transcript (Entrez)NM_015117
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_187571
Consensus coding sequences : CCDS (NCBI)ZC3H3
Cluster EST : UnigeneHs.521915 [ NCBI ]
CGAP (NCI)Hs.521915
Alternative Splicing GalleryENSG00000014164
Gene ExpressionZC3H3 [ NCBI-GEO ]   ZC3H3 [ EBI - ARRAY_EXPRESS ]   ZC3H3 [ SEEK ]   ZC3H3 [ MEM ]
Gene Expression Viewer (FireBrowse)ZC3H3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23144
GTEX Portal (Tissue expression)ZC3H3
Human Protein AtlasENSG00000014164-ZC3H3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IXZ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IXZ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IXZ2
Splice isoforms : SwissVarQ8IXZ2
PhosPhoSitePlusQ8IXZ2
Domaine pattern : Prosite (Expaxy)ZF_C3H1 (PS50103)   
Domains : Interpro (EBI)Znf_CCCH   
Domain families : Pfam (Sanger)zf-CCCH (PF00642)   
Domain families : Pfam (NCBI)pfam00642   
Domain families : Smart (EMBL)ZnF_C3H1 (SM00356)  
Conserved Domain (NCBI)ZC3H3
DMDM Disease mutations23144
Blocks (Seattle)ZC3H3
SuperfamilyQ8IXZ2
Human Protein Atlas [tissue]ENSG00000014164-ZC3H3 [tissue]
Peptide AtlasQ8IXZ2
HPRD15697
IPIIPI00410013   IPI00384232   IPI00983919   
Protein Interaction databases
DIP (DOE-UCLA)Q8IXZ2
IntAct (EBI)Q8IXZ2
FunCoupENSG00000014164
BioGRIDZC3H3
STRING (EMBL)ZC3H3
ZODIACZC3H3
Ontologies - Pathways
QuickGOQ8IXZ2
Ontology : AmiGOmolecular_function  DNA binding  RNA binding  endoribonuclease activity  nucleus  mRNA cleavage and polyadenylation specificity factor complex  mRNA polyadenylation  regulation of mRNA export from nucleus  poly(A)+ mRNA export from nucleus  positive regulation of activin receptor signaling pathway  metal ion binding  R-SMAD binding  RNA phosphodiester bond hydrolysis, endonucleolytic  
Ontology : EGO-EBImolecular_function  DNA binding  RNA binding  endoribonuclease activity  nucleus  mRNA cleavage and polyadenylation specificity factor complex  mRNA polyadenylation  regulation of mRNA export from nucleus  poly(A)+ mRNA export from nucleus  positive regulation of activin receptor signaling pathway  metal ion binding  R-SMAD binding  RNA phosphodiester bond hydrolysis, endonucleolytic  
NDEx NetworkZC3H3
Atlas of Cancer Signalling NetworkZC3H3
Wikipedia pathwaysZC3H3
Orthology - Evolution
OrthoDB23144
GeneTree (enSembl)ENSG00000014164
Phylogenetic Trees/Animal Genes : TreeFamZC3H3
HOVERGENQ8IXZ2
HOGENOMQ8IXZ2
Homologs : HomoloGeneZC3H3
Homology/Alignments : Family Browser (UCSC)ZC3H3
Gene fusions - Rearrangements
Fusion: TCGAZC3H3 YY1
Fusion: TCGAZC3H3 KLK3
Fusion: TCGAZC3H3 KIAA0907
Fusion: TCGAZC3H3 PYCRL
Fusion: Tumor Portal ZC3H3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZC3H3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZC3H3
dbVarZC3H3
ClinVarZC3H3
1000_GenomesZC3H3 
Exome Variant ServerZC3H3
ExAC (Exome Aggregation Consortium)ENSG00000014164
GNOMAD BrowserENSG00000014164
Genetic variants : HAPMAP23144
Genomic Variants (DGV)ZC3H3 [DGVbeta]
DECIPHERZC3H3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZC3H3 
Mutations
ICGC Data PortalZC3H3 
TCGA Data PortalZC3H3 
Broad Tumor PortalZC3H3
OASIS PortalZC3H3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZC3H3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZC3H3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZC3H3
DgiDB (Drug Gene Interaction Database)ZC3H3
DoCM (Curated mutations)ZC3H3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZC3H3 (select a term)
intoGenZC3H3
Cancer3DZC3H3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZC3H3
Genetic Testing Registry ZC3H3
NextProtQ8IXZ2 [Medical]
TSGene23144
GENETestsZC3H3
Target ValidationZC3H3
Huge Navigator ZC3H3 [HugePedia]
snp3D : Map Gene to Disease23144
BioCentury BCIQZC3H3
ClinGenZC3H3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23144
Chemical/Pharm GKB GenePA134933089
Clinical trialZC3H3
Miscellaneous
canSAR (ICR)ZC3H3 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZC3H3
EVEXZC3H3
GoPubMedZC3H3
iHOPZC3H3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:36:17 CET 2017

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