Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZC3H8 (zinc finger CCCH-type containing 8)

Identity

Alias_namesZC3HDC8
zinc finger CCCH-type domain containing 8
Alias_symbol (synonym)Fliz1
Other alias
HGNC (Hugo) ZC3H8
LocusID (NCBI) 84524
Atlas_Id 75887
Location 2q14.1  [Link to chromosome band 2q14]
Location_base_pair Starts at 112215863 and ends at 112255087 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CC2D1B (1p32.3) / ZC3H8 (2q13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZC3H8   30941
Cards
Entrez_Gene (NCBI)ZC3H8  84524  zinc finger CCCH-type containing 8
AliasesFliz1; ZC3HDC8
GeneCards (Weizmann)ZC3H8
Ensembl hg19 (Hinxton)ENSG00000144161 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144161 [Gene_View]  chr2:112215863-112255087 [Contig_View]  ZC3H8 [Vega]
ICGC DataPortalENSG00000144161
TCGA cBioPortalZC3H8
AceView (NCBI)ZC3H8
Genatlas (Paris)ZC3H8
WikiGenes84524
SOURCE (Princeton)ZC3H8
Genetics Home Reference (NIH)ZC3H8
Genomic and cartography
GoldenPath hg38 (UCSC)ZC3H8  -     chr2:112215863-112255087 -  2q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZC3H8  -     2q14.1   [Description]    (hg19-Feb_2009)
EnsemblZC3H8 - 2q14.1 [CytoView hg19]  ZC3H8 - 2q14.1 [CytoView hg38]
Mapping of homologs : NCBIZC3H8 [Mapview hg19]  ZC3H8 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF334161 AK315329 BC032001 BG773518 CV574571
RefSeq transcript (Entrez)NM_032494
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZC3H8
Cluster EST : UnigeneHs.418416 [ NCBI ]
CGAP (NCI)Hs.418416
Alternative Splicing GalleryENSG00000144161
Gene ExpressionZC3H8 [ NCBI-GEO ]   ZC3H8 [ EBI - ARRAY_EXPRESS ]   ZC3H8 [ SEEK ]   ZC3H8 [ MEM ]
Gene Expression Viewer (FireBrowse)ZC3H8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84524
GTEX Portal (Tissue expression)ZC3H8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5P1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5P1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5P1
Splice isoforms : SwissVarQ8N5P1
PhosPhoSitePlusQ8N5P1
Domaine pattern : Prosite (Expaxy)ZF_C3H1 (PS50103)   
Domains : Interpro (EBI)Znf_CCCH   
Domain families : Pfam (Sanger)zf-CCCH (PF00642)   
Domain families : Pfam (NCBI)pfam00642   
Domain families : Smart (EMBL)ZnF_C3H1 (SM00356)  
Conserved Domain (NCBI)ZC3H8
DMDM Disease mutations84524
Blocks (Seattle)ZC3H8
SuperfamilyQ8N5P1
Human Protein AtlasENSG00000144161
Peptide AtlasQ8N5P1
HPRD11695
IPIIPI00307760   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5P1
IntAct (EBI)Q8N5P1
FunCoupENSG00000144161
BioGRIDZC3H8
STRING (EMBL)ZC3H8
ZODIACZC3H8
Ontologies - Pathways
QuickGOQ8N5P1
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  apoptotic process  transcription elongation factor complex  Cajal body  nuclear body  negative regulation of T cell differentiation in thymus  transcriptionally active chromatin  histone locus body  snRNA transcription from RNA polymerase II promoter  snRNA transcription from RNA polymerase II promoter  snRNA transcription from RNA polymerase III promoter  T cell homeostasis  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase III promoter  response to antibiotic  metal ion binding  positive regulation of thymocyte apoptotic process  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  apoptotic process  transcription elongation factor complex  Cajal body  nuclear body  negative regulation of T cell differentiation in thymus  transcriptionally active chromatin  histone locus body  snRNA transcription from RNA polymerase II promoter  snRNA transcription from RNA polymerase II promoter  snRNA transcription from RNA polymerase III promoter  T cell homeostasis  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase III promoter  response to antibiotic  metal ion binding  positive regulation of thymocyte apoptotic process  
NDEx NetworkZC3H8
Atlas of Cancer Signalling NetworkZC3H8
Wikipedia pathwaysZC3H8
Orthology - Evolution
OrthoDB84524
GeneTree (enSembl)ENSG00000144161
Phylogenetic Trees/Animal Genes : TreeFamZC3H8
HOVERGENQ8N5P1
HOGENOMQ8N5P1
Homologs : HomoloGeneZC3H8
Homology/Alignments : Family Browser (UCSC)ZC3H8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZC3H8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZC3H8
dbVarZC3H8
ClinVarZC3H8
1000_GenomesZC3H8 
Exome Variant ServerZC3H8
ExAC (Exome Aggregation Consortium)ZC3H8 (select the gene name)
Genetic variants : HAPMAP84524
Genomic Variants (DGV)ZC3H8 [DGVbeta]
DECIPHERZC3H8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZC3H8 
Mutations
ICGC Data PortalZC3H8 
TCGA Data PortalZC3H8 
Broad Tumor PortalZC3H8
OASIS PortalZC3H8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZC3H8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZC3H8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZC3H8
DgiDB (Drug Gene Interaction Database)ZC3H8
DoCM (Curated mutations)ZC3H8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZC3H8 (select a term)
intoGenZC3H8
Cancer3DZC3H8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZC3H8
Genetic Testing Registry ZC3H8
NextProtQ8N5P1 [Medical]
TSGene84524
GENETestsZC3H8
Target ValidationZC3H8
Huge Navigator ZC3H8 [HugePedia]
snp3D : Map Gene to Disease84524
BioCentury BCIQZC3H8
ClinGenZC3H8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84524
Chemical/Pharm GKB GenePA134956342
Clinical trialZC3H8
Miscellaneous
canSAR (ICR)ZC3H8 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZC3H8
EVEXZC3H8
GoPubMedZC3H8
iHOPZC3H8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:49:32 CEST 2017

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