Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ZC4H2 (zinc finger C4H2-type containing)

Identity

Alias_namesKIAA1166
WWS
KIAA1166
Wieacker-Wolff syndrome
zinc finger, C4H2 domain containing
Alias_symbol (synonym)HCA127
Other aliasWRWF
HGNC (Hugo) ZC4H2
LocusID (NCBI) 55906
Atlas_Id 40793
Location Xq11.2  [Link to chromosome band Xq11]
Location_base_pair Starts at 64915802 and ends at 65034744 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AL109749.1 () / ZC4H2 (Xq11.2)RAD21 (8q24.11) / ZC4H2 (Xq11.2)ZC4H2 (Xq11.2) / JOSD1 (22q13.1)
ZMYND8 (20q13.12) / ZC4H2 (Xq11.2)AL109749.1 ZC4H2 Xq11.2ZMYND8 20q13.12 / ZC4H2 Xq11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZC4H2   24931
Cards
Entrez_Gene (NCBI)ZC4H2  55906  zinc finger C4H2-type containing
AliasesHCA127; KIAA1166; WRWF; WWS
GeneCards (Weizmann)ZC4H2
Ensembl hg19 (Hinxton)ENSG00000126970 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126970 [Gene_View]  chrX:64915802-65034744 [Contig_View]  ZC4H2 [Vega]
ICGC DataPortalENSG00000126970
TCGA cBioPortalZC4H2
AceView (NCBI)ZC4H2
Genatlas (Paris)ZC4H2
WikiGenes55906
SOURCE (Princeton)ZC4H2
Genetics Home Reference (NIH)ZC4H2
Genomic and cartography
GoldenPath hg38 (UCSC)ZC4H2  -     chrX:64915802-65034744 -  Xq11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZC4H2  -     Xq11.2   [Description]    (hg19-Feb_2009)
EnsemblZC4H2 - Xq11.2 [CytoView hg19]  ZC4H2 - Xq11.2 [CytoView hg38]
Mapping of homologs : NCBIZC4H2 [Mapview hg19]  ZC4H2 [Mapview hg38]
OMIM300897   
Gene and transcription
Genbank (Entrez)AB032992 AF270491 AK001547 AK022807 AK022918
RefSeq transcript (Entrez)NM_001178032 NM_001178033 NM_001243804 NM_018684
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZC4H2
Cluster EST : UnigeneHs.28249 [ NCBI ]
CGAP (NCI)Hs.28249
Alternative Splicing GalleryENSG00000126970
Gene ExpressionZC4H2 [ NCBI-GEO ]   ZC4H2 [ EBI - ARRAY_EXPRESS ]   ZC4H2 [ SEEK ]   ZC4H2 [ MEM ]
Gene Expression Viewer (FireBrowse)ZC4H2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55906
GTEX Portal (Tissue expression)ZC4H2
Human Protein AtlasENSG00000126970-ZC4H2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQZ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQZ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQZ6
Splice isoforms : SwissVarQ9NQZ6
PhosPhoSitePlusQ9NQZ6
Domains : Interpro (EBI)Znf-C4H2   
Domain families : Pfam (Sanger)zf-C4H2 (PF10146)   
Domain families : Pfam (NCBI)pfam10146   
Conserved Domain (NCBI)ZC4H2
DMDM Disease mutations55906
Blocks (Seattle)ZC4H2
SuperfamilyQ9NQZ6
Human Protein Atlas [tissue]ENSG00000126970-ZC4H2 [tissue]
Peptide AtlasQ9NQZ6
HPRD06584
IPIIPI00032956   IPI01010774   IPI00472931   IPI00376050   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQZ6
IntAct (EBI)Q9NQZ6
FunCoupENSG00000126970
BioGRIDZC4H2
STRING (EMBL)ZC4H2
ZODIACZC4H2
Ontologies - Pathways
QuickGOQ9NQZ6
Ontology : AmiGOprotein binding  nucleus  cytoplasm  nervous system development  neuromuscular junction development  spinal cord motor neuron differentiation  cell junction  postsynaptic membrane  metal ion binding  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  nervous system development  neuromuscular junction development  spinal cord motor neuron differentiation  cell junction  postsynaptic membrane  metal ion binding  
NDEx NetworkZC4H2
Atlas of Cancer Signalling NetworkZC4H2
Wikipedia pathwaysZC4H2
Orthology - Evolution
OrthoDB55906
GeneTree (enSembl)ENSG00000126970
Phylogenetic Trees/Animal Genes : TreeFamZC4H2
HOVERGENQ9NQZ6
HOGENOMQ9NQZ6
Homologs : HomoloGeneZC4H2
Homology/Alignments : Family Browser (UCSC)ZC4H2
Gene fusions - Rearrangements
Fusion : MitelmanZMYND8/ZC4H2 [20q13.12/Xq11.2]  [t(X;20)(q11;q13)]  
Fusion: TCGA_MDACCAL109749.1 ZC4H2 Xq11.2 BRCA
Fusion: TCGA_MDACCZMYND8 20q13.12 ZC4H2 Xq11.2 BRCA
Tumor Fusion PortalZC4H2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZC4H2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZC4H2
dbVarZC4H2
ClinVarZC4H2
1000_GenomesZC4H2 
Exome Variant ServerZC4H2
ExAC (Exome Aggregation Consortium)ENSG00000126970
GNOMAD BrowserENSG00000126970
Genetic variants : HAPMAP55906
Genomic Variants (DGV)ZC4H2 [DGVbeta]
DECIPHERZC4H2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZC4H2 
Mutations
ICGC Data PortalZC4H2 
TCGA Data PortalZC4H2 
Broad Tumor PortalZC4H2
OASIS PortalZC4H2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZC4H2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZC4H2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch ZC4H2
DgiDB (Drug Gene Interaction Database)ZC4H2
DoCM (Curated mutations)ZC4H2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZC4H2 (select a term)
intoGenZC4H2
Cancer3DZC4H2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300897   
Orphanet3036   
DisGeNETZC4H2
MedgenZC4H2
Genetic Testing Registry ZC4H2
NextProtQ9NQZ6 [Medical]
TSGene55906
GENETestsZC4H2
Target ValidationZC4H2
Huge Navigator ZC4H2 [HugePedia]
snp3D : Map Gene to Disease55906
BioCentury BCIQZC4H2
ClinGenZC4H2 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55906
Chemical/Pharm GKB GenePA164727643
Clinical trialZC4H2
Miscellaneous
canSAR (ICR)ZC4H2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZC4H2
EVEXZC4H2
GoPubMedZC4H2
iHOPZC4H2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:42:10 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.