Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZCCHC11 (zinc finger CCHC-type containing 11)

Identity

Alias_symbol (synonym)KIAA0191
PAPD3
TUT4
Other alias
HGNC (Hugo) ZCCHC11
LocusID (NCBI) 23318
Atlas_Id 51599
Location 1p32.3  [Link to chromosome band 1p32]
Location_base_pair Starts at 52423276 and ends at 52553090 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HSPB11 (1p32.3) / ZCCHC11 (1p32.3)SLC38A10 (17q25.3) / ZCCHC11 (1p32.3)TCEB3 (1p36.11) / ZCCHC11 (1p32.3)
USP15 (12q14.1) / ZCCHC11 (1p32.3)ZCCHC11 (1p32.3) / ELAVL4 (1p33)ZCCHC11 (1p32.3) / USP15 (12q14.1)
HSPB11 1p32.3 / ZCCHC11 1p32.3TCEB3 1p36.11 / ZCCHC11 1p32.3ZCCHC11 1p32.3 / ELAVL4 1p33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZCCHC11   28981
Cards
Entrez_Gene (NCBI)ZCCHC11  23318  zinc finger CCHC-type containing 11
AliasesPAPD3; TUT4
GeneCards (Weizmann)ZCCHC11
Ensembl hg19 (Hinxton)ENSG00000134744 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134744 [Gene_View]  chr1:52423276-52553090 [Contig_View]  ZCCHC11 [Vega]
ICGC DataPortalENSG00000134744
TCGA cBioPortalZCCHC11
AceView (NCBI)ZCCHC11
Genatlas (Paris)ZCCHC11
WikiGenes23318
SOURCE (Princeton)ZCCHC11
Genetics Home Reference (NIH)ZCCHC11
Genomic and cartography
GoldenPath hg38 (UCSC)ZCCHC11  -     chr1:52423276-52553090 -  1p32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZCCHC11  -     1p32.3   [Description]    (hg19-Feb_2009)
EnsemblZCCHC11 - 1p32.3 [CytoView hg19]  ZCCHC11 - 1p32.3 [CytoView hg38]
Mapping of homologs : NCBIZCCHC11 [Mapview hg19]  ZCCHC11 [Mapview hg38]
OMIM613692   
Gene and transcription
Genbank (Entrez)AK025698 AK095733 AK124868 AK307579 AK308427
RefSeq transcript (Entrez)NM_001009881 NM_001009882 NM_015269
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZCCHC11
Cluster EST : UnigeneHs.655407 [ NCBI ]
CGAP (NCI)Hs.655407
Alternative Splicing GalleryENSG00000134744
Gene ExpressionZCCHC11 [ NCBI-GEO ]   ZCCHC11 [ EBI - ARRAY_EXPRESS ]   ZCCHC11 [ SEEK ]   ZCCHC11 [ MEM ]
Gene Expression Viewer (FireBrowse)ZCCHC11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23318
GTEX Portal (Tissue expression)ZCCHC11
Human Protein AtlasENSG00000134744-ZCCHC11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TAX3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TAX3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TAX3
Splice isoforms : SwissVarQ5TAX3
Catalytic activity : Enzyme2.7.7.52 [ Enzyme-Expasy ]   2.7.7.522.7.7.52 [ IntEnz-EBI ]   2.7.7.52 [ BRENDA ]   2.7.7.52 [ KEGG ]   
PhosPhoSitePlusQ5TAX3
Domaine pattern : Prosite (Expaxy)ZF_CCHC (PS50158)    ZINC_FINGER_C2H2_1 (PS00028)   
Domains : Interpro (EBI)PAP_assoc    Polymerase_NTP_transf_dom    Znf_CCHC   
Domain families : Pfam (Sanger)NTP_transf_2 (PF01909)    PAP_assoc (PF03828)    zf-CCHC (PF00098)   
Domain families : Pfam (NCBI)pfam01909    pfam03828    pfam00098   
Domain families : Smart (EMBL)ZnF_C2HC (SM00343)  
Conserved Domain (NCBI)ZCCHC11
DMDM Disease mutations23318
Blocks (Seattle)ZCCHC11
SuperfamilyQ5TAX3
Human Protein Atlas [tissue]ENSG00000134744-ZCCHC11 [tissue]
Peptide AtlasQ5TAX3
HPRD15700
IPIIPI00289861   IPI00935848   IPI00977508   IPI00981070   IPI00550431   IPI00981667   IPI00983723   IPI00983132   IPI00977601   IPI00975609   IPI00976712   IPI00979693   IPI00975697   IPI00985026   
Protein Interaction databases
DIP (DOE-UCLA)Q5TAX3
IntAct (EBI)Q5TAX3
FunCoupENSG00000134744
BioGRIDZCCHC11
STRING (EMBL)ZCCHC11
ZODIACZCCHC11
Ontologies - Pathways
QuickGOQ5TAX3
Ontology : AmiGORNA binding  protein binding  extracellular space  nucleolus  cytoplasm  cytosol  zinc ion binding  miRNA metabolic process  miRNA catabolic process  stem cell population maintenance  pre-miRNA processing  RNA 3'-end processing  RNA uridylyltransferase activity  extracellular exosome  histone mRNA catabolic process  
Ontology : EGO-EBIRNA binding  protein binding  extracellular space  nucleolus  cytoplasm  cytosol  zinc ion binding  miRNA metabolic process  miRNA catabolic process  stem cell population maintenance  pre-miRNA processing  RNA 3'-end processing  RNA uridylyltransferase activity  extracellular exosome  histone mRNA catabolic process  
NDEx NetworkZCCHC11
Atlas of Cancer Signalling NetworkZCCHC11
Wikipedia pathwaysZCCHC11
Orthology - Evolution
OrthoDB23318
GeneTree (enSembl)ENSG00000134744
Phylogenetic Trees/Animal Genes : TreeFamZCCHC11
HOVERGENQ5TAX3
HOGENOMQ5TAX3
Homologs : HomoloGeneZCCHC11
Homology/Alignments : Family Browser (UCSC)ZCCHC11
Gene fusions - Rearrangements
Fusion : MitelmanHSPB11/ZCCHC11 [1p32.3/1p32.3]  [t(1;1)(p32;p32)]  
Fusion : MitelmanSLC38A10/ZCCHC11 [17q25.3/1p32.3]  [t(1;17)(p32;q25)]  
Fusion : MitelmanTCEB3/ZCCHC11 [1p36.11/1p32.3]  [t(1;1)(p32;p36)]  
Fusion : MitelmanZCCHC11/ELAVL4 [1p32.3/1p33]  [t(1;1)(p32;p33)]  
Fusion: TCGA_MDACCHSPB11 1p32.3 ZCCHC11 1p32.3 HNSC
Fusion: TCGA_MDACCTCEB3 1p36.11 ZCCHC11 1p32.3 PRAD
Fusion: TCGA_MDACCZCCHC11 1p32.3 ELAVL4 1p33 BRCA
Tumor Fusion PortalZCCHC11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZCCHC11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZCCHC11
dbVarZCCHC11
ClinVarZCCHC11
1000_GenomesZCCHC11 
Exome Variant ServerZCCHC11
ExAC (Exome Aggregation Consortium)ENSG00000134744
GNOMAD BrowserENSG00000134744
Genetic variants : HAPMAP23318
Genomic Variants (DGV)ZCCHC11 [DGVbeta]
DECIPHERZCCHC11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZCCHC11 
Mutations
ICGC Data PortalZCCHC11 
TCGA Data PortalZCCHC11 
Broad Tumor PortalZCCHC11
OASIS PortalZCCHC11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZCCHC11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZCCHC11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZCCHC11
DgiDB (Drug Gene Interaction Database)ZCCHC11
DoCM (Curated mutations)ZCCHC11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZCCHC11 (select a term)
intoGenZCCHC11
Cancer3DZCCHC11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613692   
Orphanet
DisGeNETZCCHC11
MedgenZCCHC11
Genetic Testing Registry ZCCHC11
NextProtQ5TAX3 [Medical]
TSGene23318
GENETestsZCCHC11
Target ValidationZCCHC11
Huge Navigator ZCCHC11 [HugePedia]
snp3D : Map Gene to Disease23318
BioCentury BCIQZCCHC11
ClinGenZCCHC11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23318
Chemical/Pharm GKB GenePA134918178
Clinical trialZCCHC11
Miscellaneous
canSAR (ICR)ZCCHC11 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZCCHC11
EVEXZCCHC11
GoPubMedZCCHC11
iHOPZCCHC11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:42:10 CET 2017

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