ZCCHC12 (zinc finger CCHC-type containing 12)

2013-07-01  

Identity

HGNC
ZCCHC12
LOCATION
Xq24
LOCUSID
170261
ALIAS
PNMA7A,SIZN,SIZN1

Other Information

Locus ID:

NCBI: 170261
MIM: 300701
HGNC: 27273
Ensembl: ENSG00000174460

Variants:

dbSNP: 170261
ClinVar: 170261
TCGA: ENSG00000174460
COSMIC: ZCCHC12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174460ENST00000310164Q6PEW1

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
194169672009SUMO interaction motifs in Sizn1 are required for promyelocytic leukemia protein nuclear body localization and for transcriptional activation.13
187983192008Evidence that SIZN1 is a candidate X-linked mental retardation gene.7
195787172009Human ZCCHC12 activates AP-1 and CREB signaling as a transcriptional co-activator.1
217393072012ZCCHC12, a potential molecular marker of papillary thyroid carcinoma: a preliminary study.1
284249032017ZCCHC12, a novel oncogene in papillary thyroid cancer.1

Citation

Dessen P

ZCCHC12 (zinc finger CCHC-type containing 12)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53423/zcchc12