ZCCHC4 (zinc finger CCHC-type containing 4)

2019-05-01 Affiliation

Identity

HGNC

ZCCHC4

LOCATION

4p15.2

LOCUSID

29063

ALIAS

HSPC052,ZGRF4

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 29063
MIM: 611792
HGNC: 22917
Ensembl: ENSG00000168228

Variants:

dbSNP: 29063
ClinVar: 29063
TCGA: ENSG00000168228
COSMIC: ZCCHC4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000168228	ENST00000302874	Q9H5U6
ENSG00000168228	ENST00000505412	H0Y8V8
ENSG00000168228	ENST00000507760	Q9H5U6
ENSG00000168228	ENST00000612982	A0A087X0K5

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
30531910	2019	N^6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation.	25
31799605	2020	The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA.	2
31695039	2019	Structure and regulation of ZCCHC4 in m⁶A-methylation of 28S rRNA.	1

Citation

Dessen P

ZCCHC4 (zinc finger CCHC-type containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2019-05-01

Online version: http://atlasgeneticsoncology.org/gene/57985/zcchc4