Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZCCHC8 (zinc finger CCHC-type containing 8)

Identity

Alias_symbol (synonym)DKFZp434E2220
Other alias-
HGNC (Hugo) ZCCHC8
LocusID (NCBI) 55596
Atlas_Id 55066
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 122956146 and ends at 122985620 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PTPRT (20q12) / ZCCHC8 (12q24.31)ZCCHC8 (12q24.31) / ROS1 (6q22.1)ZCCHC8 (12q24.31) / RSRC2 (12q24.31)
ZCCHC8 12q24.31 / ROS1 6q22.1ZCCHC8 12q24.31 / RSRC2 12q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZCCHC8   25265
Cards
Entrez_Gene (NCBI)ZCCHC8  55596  zinc finger CCHC-type containing 8
Aliases
GeneCards (Weizmann)ZCCHC8
Ensembl hg19 (Hinxton)ENSG00000033030 [Gene_View]  chr12:122956146-122985620 [Contig_View]  ZCCHC8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000033030 [Gene_View]  chr12:122956146-122985620 [Contig_View]  ZCCHC8 [Vega]
ICGC DataPortalENSG00000033030
TCGA cBioPortalZCCHC8
AceView (NCBI)ZCCHC8
Genatlas (Paris)ZCCHC8
WikiGenes55596
SOURCE (Princeton)ZCCHC8
Genetics Home Reference (NIH)ZCCHC8
Genomic and cartography
GoldenPath hg19 (UCSC)ZCCHC8  -     chr12:122956146-122985620 -  12q24.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZCCHC8  -     12q24.31   [Description]    (hg38-Dec_2013)
EnsemblZCCHC8 - 12q24.31 [CytoView hg19]  ZCCHC8 - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBIZCCHC8 [Mapview hg19]  ZCCHC8 [Mapview hg38]
OMIM616381   
Gene and transcription
Genbank (Entrez)AA447641 AK026831 AK027702 AK074638 AK291174
RefSeq transcript (Entrez)NM_017612
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929386
Consensus coding sequences : CCDS (NCBI)ZCCHC8
Cluster EST : UnigeneHs.37706 [ NCBI ]
CGAP (NCI)Hs.37706
Alternative Splicing GalleryENSG00000033030
Gene ExpressionZCCHC8 [ NCBI-GEO ]   ZCCHC8 [ EBI - ARRAY_EXPRESS ]   ZCCHC8 [ SEEK ]   ZCCHC8 [ MEM ]
Gene Expression Viewer (FireBrowse)ZCCHC8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55596
GTEX Portal (Tissue expression)ZCCHC8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6NZY4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6NZY4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6NZY4
Splice isoforms : SwissVarQ6NZY4
PhosPhoSitePlusQ6NZY4
Domaine pattern : Prosite (Expaxy)ZF_CCHC (PS50158)   
Domains : Interpro (EBI)PSP    Znf_CCHC   
Domain families : Pfam (Sanger)PSP (PF04046)    zf-CCHC (PF00098)   
Domain families : Pfam (NCBI)pfam04046    pfam00098   
Domain families : Smart (EMBL)PSP (SM00581)  ZnF_C2HC (SM00343)  
Conserved Domain (NCBI)ZCCHC8
DMDM Disease mutations55596
Blocks (Seattle)ZCCHC8
SuperfamilyQ6NZY4
Human Protein AtlasENSG00000033030
Peptide AtlasQ6NZY4
HPRD11698
IPIIPI00556594   IPI00166422   IPI01014790   IPI01013833   IPI01015185   IPI01012888   
Protein Interaction databases
DIP (DOE-UCLA)Q6NZY4
IntAct (EBI)Q6NZY4
FunCoupENSG00000033030
BioGRIDZCCHC8
STRING (EMBL)ZCCHC8
ZODIACZCCHC8
Ontologies - Pathways
QuickGOQ6NZY4
Ontology : AmiGOmRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  zinc ion binding  poly(A) RNA binding  catalytic step 2 spliceosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  protein binding  nucleus  nucleoplasm  zinc ion binding  poly(A) RNA binding  catalytic step 2 spliceosome  
NDEx NetworkZCCHC8
Atlas of Cancer Signalling NetworkZCCHC8
Wikipedia pathwaysZCCHC8
Orthology - Evolution
OrthoDB55596
GeneTree (enSembl)ENSG00000033030
Phylogenetic Trees/Animal Genes : TreeFamZCCHC8
HOVERGENQ6NZY4
HOGENOMQ6NZY4
Homologs : HomoloGeneZCCHC8
Homology/Alignments : Family Browser (UCSC)ZCCHC8
Gene fusions - Rearrangements
Fusion : MitelmanZCCHC8/RSRC2 [12q24.31/12q24.31]  
Fusion: TCGAZCCHC8 12q24.31 RSRC2 12q24.31 BLCA BRCA HNSC KIRC LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZCCHC8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZCCHC8
dbVarZCCHC8
ClinVarZCCHC8
1000_GenomesZCCHC8 
Exome Variant ServerZCCHC8
ExAC (Exome Aggregation Consortium)ZCCHC8 (select the gene name)
Genetic variants : HAPMAP55596
Genomic Variants (DGV)ZCCHC8 [DGVbeta]
DECIPHER (Syndromes)12:122956146-122985620  ENSG00000033030
CONAN: Copy Number AnalysisZCCHC8 
Mutations
ICGC Data PortalZCCHC8 
TCGA Data PortalZCCHC8 
Broad Tumor PortalZCCHC8
OASIS PortalZCCHC8 [ Somatic mutations - Copy number]
Cancer Gene: CensusZCCHC8 
Somatic Mutations in Cancer : COSMICZCCHC8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZCCHC8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZCCHC8
DgiDB (Drug Gene Interaction Database)ZCCHC8
DoCM (Curated mutations)ZCCHC8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZCCHC8 (select a term)
intoGenZCCHC8
Cancer3DZCCHC8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616381   
Orphanet
MedgenZCCHC8
Genetic Testing Registry ZCCHC8
NextProtQ6NZY4 [Medical]
TSGene55596
GENETestsZCCHC8
Huge Navigator ZCCHC8 [HugePedia]
snp3D : Map Gene to Disease55596
BioCentury BCIQZCCHC8
ClinGenZCCHC8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55596
Chemical/Pharm GKB GenePA134889410
Clinical trialZCCHC8
Miscellaneous
canSAR (ICR)ZCCHC8 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZCCHC8
EVEXZCCHC8
GoPubMedZCCHC8
iHOPZCCHC8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:25:27 CEST 2017

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