ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)

2007-02-01  

Identity

HGNC
LOCATION
12q21.2
LOCUSID
ALIAS
DHHC-17,DHHC17,HIP14,HIP3,HSPC294,HYPH
FUSION GENES

Other Information

Locus ID:

NCBI: 23390
MIM: 607799
HGNC: 18412
Ensembl: ENSG00000186908

Variants:

dbSNP: 23390
ClinVar: 23390
TCGA: ENSG00000186908
COSMIC: ZDHHC17

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186908ENST00000426126Q8IUH5
ENSG00000186908ENST00000546778F8VUG7
ENSG00000186908ENST00000547604H0YIN1
ENSG00000186908ENST00000547620H0YHF0
ENSG00000186908ENST00000549682F8VPW2
ENSG00000186908ENST00000549944H0YI74
ENSG00000186908ENST00000550163H0YIP7
ENSG00000186908ENST00000550876F8VX48
ENSG00000186908ENST00000551407H0YHW0
ENSG00000186908ENST00000552453H0YIK0

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
154898872004Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase.43
154898872004Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase.43
205079962010Multiple palmitoyltransferases are required for palmitoylation-dependent regulation of large conductance calcium- and voltage-activated potassium channels.28
187942992008Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport.25
217056572011Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis.19
247053542014The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.18
168476932006Genetic analysis of candidate genes modifying the age-at-onset in Huntington's disease.15
240017712013DHHC17 palmitoylates ClipR-59 and modulates ClipR-59 association with the plasma membrane.15
218495582011Palmitoyl acyltransferase zD17 mediates neuronal responses in acute ischemic brain injury by regulating JNK activation in a signaling module.12
199555682010Golgi-specific DHHC zinc finger protein GODZ mediates membrane Ca2+ transport.8

Citation

Dessen P

ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46045/zdhhc17