Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZDHHC21 (zinc finger, DHHC-type containing 21)

Identity

Alias_symbol (synonym)HSPC097
DNZ1
Other alias9130404H11Rik
DHHC-21
DHHC21
HGNC (Hugo) ZDHHC21
LocusID (NCBI) 340481
Atlas_Id 75911
Location 9p22.3  [Link to chromosome band 9p22]
Location_base_pair Starts at 14611069 and ends at 14693480 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NFIB (9p23) / ZDHHC21 (9p22.3)ZDHHC21 (9p22.3) / ELAVL2 (9p21.3)ZDHHC21 (9p22.3) / PRDM2 (1p36.21)
ZDHHC21 (9p22.3) / VPS37C (11q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZDHHC21   20750
Cards
Entrez_Gene (NCBI)ZDHHC21  340481  zinc finger, DHHC-type containing 21
Aliases9130404H11Rik; DHHC-21; DHHC21; DNZ1; 
HSPC097
GeneCards (Weizmann)ZDHHC21
Ensembl hg19 (Hinxton)ENSG00000175893 [Gene_View]  chr9:14611069-14693480 [Contig_View]  ZDHHC21 [Vega]
Ensembl hg38 (Hinxton)ENSG00000175893 [Gene_View]  chr9:14611069-14693480 [Contig_View]  ZDHHC21 [Vega]
ICGC DataPortalENSG00000175893
TCGA cBioPortalZDHHC21
AceView (NCBI)ZDHHC21
Genatlas (Paris)ZDHHC21
WikiGenes340481
SOURCE (Princeton)ZDHHC21
Genetics Home Reference (NIH)ZDHHC21
Genomic and cartography
GoldenPath hg19 (UCSC)ZDHHC21  -     chr9:14611069-14693480 -  9p22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZDHHC21  -     9p22.3   [Description]    (hg38-Dec_2013)
EnsemblZDHHC21 - 9p22.3 [CytoView hg19]  ZDHHC21 - 9p22.3 [CytoView hg38]
Mapping of homologs : NCBIZDHHC21 [Mapview hg19]  ZDHHC21 [Mapview hg38]
OMIM614605   
Gene and transcription
Genbank (Entrez)AF161360 AK026322 AK096860 AK124263 AK127313
RefSeq transcript (Entrez)NM_178566
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008413 NW_004929342
Consensus coding sequences : CCDS (NCBI)ZDHHC21
Cluster EST : UnigeneHs.714266 [ NCBI ]
CGAP (NCI)Hs.714266
Alternative Splicing GalleryENSG00000175893
Gene ExpressionZDHHC21 [ NCBI-GEO ]   ZDHHC21 [ EBI - ARRAY_EXPRESS ]   ZDHHC21 [ SEEK ]   ZDHHC21 [ MEM ]
Gene Expression Viewer (FireBrowse)ZDHHC21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)340481
GTEX Portal (Tissue expression)ZDHHC21
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IVQ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IVQ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IVQ6
Splice isoforms : SwissVarQ8IVQ6
Catalytic activity : Enzyme2.3.1.225 [ Enzyme-Expasy ]   2.3.1.2252.3.1.225 [ IntEnz-EBI ]   2.3.1.225 [ BRENDA ]   2.3.1.225 [ KEGG ]   
PhosPhoSitePlusQ8IVQ6
Domaine pattern : Prosite (Expaxy)ZF_DHHC (PS50216)   
Domains : Interpro (EBI)Znf_DHHC_palmitoyltrfase   
Domain families : Pfam (Sanger)zf-DHHC (PF01529)   
Domain families : Pfam (NCBI)pfam01529   
Conserved Domain (NCBI)ZDHHC21
DMDM Disease mutations340481
Blocks (Seattle)ZDHHC21
SuperfamilyQ8IVQ6
Human Protein AtlasENSG00000175893
Peptide AtlasQ8IVQ6
HPRD15716
IPIIPI00217094   IPI00383214   
Protein Interaction databases
DIP (DOE-UCLA)Q8IVQ6
IntAct (EBI)Q8IVQ6
FunCoupENSG00000175893
BioGRIDZDHHC21
STRING (EMBL)ZDHHC21
ZODIACZDHHC21
Ontologies - Pathways
QuickGOQ8IVQ6
Ontology : AmiGOGolgi membrane  hair follicle development  Golgi apparatus  plasma membrane  zinc ion binding  integral component of membrane  palmitoyltransferase activity  peptidyl-L-cysteine S-palmitoylation  protein palmitoylation  protein-cysteine S-palmitoyltransferase activity  small molecule metabolic process  nitric oxide metabolic process  sebaceous gland development  regulation of nitric-oxide synthase activity  
Ontology : EGO-EBIGolgi membrane  hair follicle development  Golgi apparatus  plasma membrane  zinc ion binding  integral component of membrane  palmitoyltransferase activity  peptidyl-L-cysteine S-palmitoylation  protein palmitoylation  protein-cysteine S-palmitoyltransferase activity  small molecule metabolic process  nitric oxide metabolic process  sebaceous gland development  regulation of nitric-oxide synthase activity  
NDEx NetworkZDHHC21
Atlas of Cancer Signalling NetworkZDHHC21
Wikipedia pathwaysZDHHC21
Orthology - Evolution
OrthoDB340481
GeneTree (enSembl)ENSG00000175893
Phylogenetic Trees/Animal Genes : TreeFamZDHHC21
HOVERGENQ8IVQ6
HOGENOMQ8IVQ6
Homologs : HomoloGeneZDHHC21
Homology/Alignments : Family Browser (UCSC)ZDHHC21
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZDHHC21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZDHHC21
dbVarZDHHC21
ClinVarZDHHC21
1000_GenomesZDHHC21 
Exome Variant ServerZDHHC21
ExAC (Exome Aggregation Consortium)ZDHHC21 (select the gene name)
Genetic variants : HAPMAP340481
Genomic Variants (DGV)ZDHHC21 [DGVbeta]
DECIPHER (Syndromes)9:14611069-14693480  ENSG00000175893
CONAN: Copy Number AnalysisZDHHC21 
Mutations
ICGC Data PortalZDHHC21 
TCGA Data PortalZDHHC21 
Broad Tumor PortalZDHHC21
OASIS PortalZDHHC21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZDHHC21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZDHHC21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZDHHC21
DgiDB (Drug Gene Interaction Database)ZDHHC21
DoCM (Curated mutations)ZDHHC21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZDHHC21 (select a term)
intoGenZDHHC21
Cancer3DZDHHC21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614605   
Orphanet
MedgenZDHHC21
Genetic Testing Registry ZDHHC21
NextProtQ8IVQ6 [Medical]
TSGene340481
GENETestsZDHHC21
Huge Navigator ZDHHC21 [HugePedia]
snp3D : Map Gene to Disease340481
BioCentury BCIQZDHHC21
ClinGenZDHHC21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD340481
Chemical/Pharm GKB GenePA134919189
Clinical trialZDHHC21
Miscellaneous
canSAR (ICR)ZDHHC21 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZDHHC21
EVEXZDHHC21
GoPubMedZDHHC21
iHOPZDHHC21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:52:16 CET 2017

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