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ZEB1 (zinc finger E-box binding homeobox 1)

Identity

Alias (NCBI)AREB6
BZP
DELTAEF1
FECD6
NIL2A
PPCD3
TCF8
ZFHEP
ZFHX1A
HGNC (Hugo) ZEB1
HGNC Alias symbBZP
ZEB
AREB6
NIL-2-A
Zfhep
Zfhx1a
FECD6
HGNC Previous nameTCF8
 PPCD3
HGNC Previous nametranscription factor 8 (represses interleukin 2 expression)
 posterior polymorphous corneal dystrophy 3
LocusID (NCBI) 6935
Atlas_Id 46166
Location 10p11.22  [Link to chromosome band 10p11]
Location_base_pair Starts at 31319216 and ends at 31529804 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACBD5 (10p12.1) / ZEB1 (10p11.22)ECT2L (6q24.1) / ZEB1 (10p11.22)EPC1 (10p11.22) / ZEB1 (10p11.22)
MIR548N (2q31.2) / ZEB1 (10p11.22)RAB31 (18p11.22) / ZEB1 (10p11.22)ZEB1 (10p11.22) / BMI1 (10p12.2)
ZEB1 (10p11.22) / SIK1 (21q22.3)ZEB1 (10p11.22) / WAC (10p12.1)ZEB1 (10p11.22) / ZEB1 (10p11.22)
ZEB1 (10p11.22) / ZNF438 (10p11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(10;10)(p11;p12) ZEB1/BMI1


External links

Nomenclature
HGNC (Hugo)ZEB1   11642
Cards
Entrez_Gene (NCBI)ZEB1    zinc finger E-box binding homeobox 1
AliasesAREB6; BZP; DELTAEF1; FECD6; 
NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A
GeneCards (Weizmann)ZEB1
Ensembl hg19 (Hinxton)ENSG00000148516 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148516 [Gene_View]  ENSG00000148516 [Sequence]  chr10:31319216-31529804 [Contig_View]  ZEB1 [Vega]
ICGC DataPortalENSG00000148516
TCGA cBioPortalZEB1
AceView (NCBI)ZEB1
Genatlas (Paris)ZEB1
SOURCE (Princeton)ZEB1
Genetics Home Reference (NIH)ZEB1
Genomic and cartography
GoldenPath hg38 (UCSC)ZEB1  -     chr10:31319216-31529804 +  10p11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZEB1  -     10p11.22   [Description]    (hg19-Feb_2009)
GoldenPathZEB1 - 10p11.22 [CytoView hg19]  ZEB1 - 10p11.22 [CytoView hg38]
ImmunoBaseENSG00000148516
Genome Data Viewer NCBIZEB1 [Mapview hg19]  
OMIM189909   609141   613270   
Gene and transcription
Genbank (Entrez)AI086650 AK091478 AK294775 AK296244 AK299541
RefSeq transcript (Entrez)NM_001128128 NM_001174093 NM_001174094 NM_001174095 NM_001174096 NM_001323638 NM_001323641 NM_001323642 NM_001323643 NM_001323644 NM_001323645 NM_001323646 NM_001323647 NM_001323648 NM_001323649 NM_001323650 NM_001323651 NM_001323652 NM_001323653 NM_001323654 NM_001323655 NM_001323656 NM_001323657 NM_001323658 NM_001323659 NM_001323660 NM_001323661 NM_001323662 NM_001323663 NM_001323664 NM_001323665 NM_001323666 NM_001323671 NM_001323672 NM_001323673 NM_001323674 NM_001323675 NM_001323676 NM_001323677 NM_001323678 NM_030751
Consensus coding sequences : CCDS (NCBI)ZEB1
Gene ExpressionZEB1 [ NCBI-GEO ]   ZEB1 [ EBI - ARRAY_EXPRESS ]   ZEB1 [ SEEK ]   ZEB1 [ MEM ]
Gene Expression Viewer (FireBrowse)ZEB1 [ Firebrowse - Broad ]
GenevisibleExpression of ZEB1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6935
GTEX Portal (Tissue expression)ZEB1
Human Protein AtlasENSG00000148516-ZEB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)ZEB1
Human Protein Atlas [tissue]ENSG00000148516-ZEB1 [tissue]
HPRD01798
Protein Interaction databases
BioGRIDZEB1
STRING (EMBL)ZEB1
ZODIACZEB1
Ontologies - Pathways
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZEB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:38:54 CEST 2021

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