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ZFAND3 (zinc finger AN1-type containing 3)

Identity

Alias_namesTEX27
testis expressed sequence 27
zinc finger, AN1-type domain 3
Alias_symbol (synonym)FLJ13222
Other alias
HGNC (Hugo) ZFAND3
LocusID (NCBI) 60685
Atlas_Id 54796
Location 6p21.2  [Link to chromosome band 6p21]
Location_base_pair Starts at 37819531 and ends at 38154623 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKAP2 (9q31.3) / ZFAND3 (6p21.2)ARNT2 (15q25.1) / ZFAND3 (6p21.2)AXL (19q13.2) / ZFAND3 (6p21.2)
BRPF3 (6p21.31) / ZFAND3 (6p21.2)CDK19 (6q21) / ZFAND3 (6p21.2)CECR2 (22q11.1) / ZFAND3 (6p21.2)
HMBOX1 (8p21.1) / ZFAND3 (6p21.2)MARCH6 (5p15.2) / ZFAND3 (6p21.2)SLC25A16 (10q21.3) / ZFAND3 (6p21.2)
ZFAND3 (6p21.2) / AL353597.1 ()ZFAND3 (6p21.2) / DNAH8 (6p21.2)ZFAND3 (6p21.2) / KCTD20 (6p21.31)
ZFAND3 (6p21.2) / RNF8 (6p21.2)ZFAND3 (6p21.2) / SLC25A37 (8p21.2)ZFAND3 (6p21.2) / TBC1D5 (3p24.3)
ARNT2 15q25.1 / ZFAND3 6p21.2BRPF3 6p21.31 / ZFAND3 6p21.2CDK19 6q21 / ZFAND3 6p21.2
ZFAND3 6p21.2 AL353597.1ZFAND3 6p21.2 / KCTD20 6p21.31ZFAND3 6p21.2 / RNF8 6p21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 8 ]
  Lung: Translocations in Small Cell Carcinoma
BRPF3/ZFAND3 (6p21)
ZFAND3/DNAH8 (6p21)
ZFAND3/KCTD20 (6p21)
ZFAND3/RNF8 (6p21)
t(6;6)(p21;q21) CDK19/ZFAND3
t(6;8)(p21;p21) HMBOX1/ZFAND3
t(6;15)(p21;q25) ARNT2/ZFAND3


External links

Nomenclature
HGNC (Hugo)ZFAND3   18019
Cards
Entrez_Gene (NCBI)ZFAND3  60685  zinc finger AN1-type containing 3
AliasesTEX27
GeneCards (Weizmann)ZFAND3
Ensembl hg19 (Hinxton)ENSG00000156639 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156639 [Gene_View]  ENSG00000156639 [Sequence]  chr6:37819531-38154623 [Contig_View]  ZFAND3 [Vega]
ICGC DataPortalENSG00000156639
TCGA cBioPortalZFAND3
AceView (NCBI)ZFAND3
Genatlas (Paris)ZFAND3
WikiGenes60685
SOURCE (Princeton)ZFAND3
Genetics Home Reference (NIH)ZFAND3
Genomic and cartography
GoldenPath hg38 (UCSC)ZFAND3  -     chr6:37819531-38154623 +  6p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFAND3  -     6p21.2   [Description]    (hg19-Feb_2009)
EnsemblZFAND3 - 6p21.2 [CytoView hg19]  ZFAND3 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBIZFAND3 [Mapview hg19]  ZFAND3 [Mapview hg38]
OMIM607455   
Gene and transcription
Genbank (Entrez)AI817165 AK023284 AK310757 AL137302 AW023961
RefSeq transcript (Entrez)NM_021943
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZFAND3
Cluster EST : UnigeneHs.36959 [ NCBI ]
CGAP (NCI)Hs.36959
Alternative Splicing GalleryENSG00000156639
Gene ExpressionZFAND3 [ NCBI-GEO ]   ZFAND3 [ EBI - ARRAY_EXPRESS ]   ZFAND3 [ SEEK ]   ZFAND3 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFAND3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)60685
GTEX Portal (Tissue expression)ZFAND3
Human Protein AtlasENSG00000156639-ZFAND3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H8U3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H8U3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H8U3
Splice isoforms : SwissVarQ9H8U3
PhosPhoSitePlusQ9H8U3
Domaine pattern : Prosite (Expaxy)ZF_A20 (PS51036)    ZF_AN1 (PS51039)   
Domains : Interpro (EBI)AN1-like_Znf    Znf_A20    Znf_AN1   
Domain families : Pfam (Sanger)zf-A20 (PF01754)    zf-AN1 (PF01428)   
Domain families : Pfam (NCBI)pfam01754    pfam01428   
Domain families : Smart (EMBL)ZnF_A20 (SM00259)  ZnF_AN1 (SM00154)  
Conserved Domain (NCBI)ZFAND3
DMDM Disease mutations60685
Blocks (Seattle)ZFAND3
PDB (SRS)1X4W   
PDB (PDBSum)1X4W   
PDB (IMB)1X4W   
PDB (RSDB)1X4W   
Structural Biology KnowledgeBase1X4W   
SCOP (Structural Classification of Proteins)1X4W   
CATH (Classification of proteins structures)1X4W   
SuperfamilyQ9H8U3
Human Protein Atlas [tissue]ENSG00000156639-ZFAND3 [tissue]
Peptide AtlasQ9H8U3
HPRD12121
IPIIPI00550013   IPI00982871   IPI00030324   IPI00645042   IPI00947186   
Protein Interaction databases
DIP (DOE-UCLA)Q9H8U3
IntAct (EBI)Q9H8U3
FunCoupENSG00000156639
BioGRIDZFAND3
STRING (EMBL)ZFAND3
ZODIACZFAND3
Ontologies - Pathways
QuickGOQ9H8U3
Ontology : AmiGODNA binding  zinc ion binding  
Ontology : EGO-EBIDNA binding  zinc ion binding  
NDEx NetworkZFAND3
Atlas of Cancer Signalling NetworkZFAND3
Wikipedia pathwaysZFAND3
Orthology - Evolution
OrthoDB60685
GeneTree (enSembl)ENSG00000156639
Phylogenetic Trees/Animal Genes : TreeFamZFAND3
HOVERGENQ9H8U3
HOGENOMQ9H8U3
Homologs : HomoloGeneZFAND3
Homology/Alignments : Family Browser (UCSC)ZFAND3
Gene fusions - Rearrangements
Fusion : MitelmanARNT2/ZFAND3 [15q25.1/6p21.2]  [t(6;15)(p21;q25)]  
Fusion : MitelmanBRPF3/ZFAND3 [6p21.31/6p21.2]  [t(6;6)(p21;p21)]  
Fusion : MitelmanCDK19/ZFAND3 [6q21/6p21.2]  [t(6;6)(p21;q21)]  
Fusion : MitelmanHMBOX1/ZFAND3 [8p21.1/6p21.2]  [t(6;8)(p21;p21)]  
Fusion : MitelmanZFAND3/DNAH8 [6p21.2/6p21.2]  [t(6;6)(p21;p21)]  
Fusion : MitelmanZFAND3/KCTD20 [6p21.2/6p21.31]  [t(6;6)(p21;p21)]  
Fusion : MitelmanZFAND3/RNF8 [6p21.2/6p21.2]  [t(6;6)(p21;p21)]  
Fusion PortalARNT2 15q25.1 ZFAND3 6p21.2 PRAD
Fusion PortalBRPF3 6p21.31 ZFAND3 6p21.2 LUAD
Fusion PortalCDK19 6q21 ZFAND3 6p21.2 BRCA
Fusion PortalZFAND3 6p21.2 AL353597.1 BLCA LUSC
Fusion PortalZFAND3 6p21.2 KCTD20 6p21.31 BRCA
Fusion PortalZFAND3 6p21.2 RNF8 6p21.2 BRCA
Fusion : QuiverZFAND3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFAND3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFAND3
dbVarZFAND3
ClinVarZFAND3
1000_GenomesZFAND3 
Exome Variant ServerZFAND3
ExAC (Exome Aggregation Consortium)ENSG00000156639
GNOMAD BrowserENSG00000156639
Varsome BrowserZFAND3
Genetic variants : HAPMAP60685
Genomic Variants (DGV)ZFAND3 [DGVbeta]
DECIPHERZFAND3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFAND3 
Mutations
ICGC Data PortalZFAND3 
TCGA Data PortalZFAND3 
Broad Tumor PortalZFAND3
OASIS PortalZFAND3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFAND3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFAND3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFAND3
DgiDB (Drug Gene Interaction Database)ZFAND3
DoCM (Curated mutations)ZFAND3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFAND3 (select a term)
intoGenZFAND3
Cancer3DZFAND3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607455   
Orphanet
DisGeNETZFAND3
MedgenZFAND3
Genetic Testing Registry ZFAND3
NextProtQ9H8U3 [Medical]
TSGene60685
GENETestsZFAND3
Target ValidationZFAND3
Huge Navigator ZFAND3 [HugePedia]
snp3D : Map Gene to Disease60685
BioCentury BCIQZFAND3
ClinGenZFAND3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD60685
Chemical/Pharm GKB GenePA38277
Clinical trialZFAND3
Miscellaneous
canSAR (ICR)ZFAND3 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFAND3
EVEXZFAND3
GoPubMedZFAND3
iHOPZFAND3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:50:57 CET 2018

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